<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation G163V
Rx II-naive
IncludeMixtures No
References 6
Patients 16
Isolates 16
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Rousseau (2006)Pt2903PS052MB1DQ369987None   D25E, M50I, I72V, F100Y, L101I, T112V, T125A, K136Q, G163V, K173R, V201I, T218I, L234I, A265V, R269K, D278A, S283GC
Matthews (2008)PS052PS052FJ199633None   D25E, M50I, I72V, F100Y, L101I, T112V, T125A, K136Q, G163V, K173R, V201I, T218I, L234I, A265V, R269K, D278A, S283GC
 PS125PS125FJ199697None   E10X, D25E, M50I, Q95R, F100Y, L101I, T112I, S119P, T125A, K136Q, G163V, H171R, V201I, T218I, L234I, R269K, D278A, S283GC
 PS126PS126FJ199698None   D25E, M50I, Q95R, F100Y, L101I, T112I, S119P, T125A, K136Q, G163V, H171R, V201I, T218I, L234I, R269K, D278A, S283GC
Monleau (2012)DRC-446DRC-446JQ250566None   K14R, K34KR, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, G163V, G193E, V201I, L234I, D278A, S283G, D286NC
Bessong (2013)08BBVCT0908BBVCT09HM569274None   K14R, D25E, V31I, F100Y, L101I, T112V, T124N, T125A, K136Q, G163V, V201I, T206S, T218I, L234I, A265V, R269K, D278A, S283GC
 08MB14ZA08MB14ZAHM569302None   V31I, M50I, I72V, L101I, T112V, T124S, T125V, K136Q, G163V, V201I, T206S, T218I, L234I, I251L, A265V, R269K, D278A, S283GC
Mulu (2015)ETH-G-5681ETH-G-5681KF959763None  L74MD25E, V31I, L101I, T112V, T124A, T125A, G134GD, K136Q, G163V, T218I, L234IC
 ETH-G-5769ETH-G-5769KF959770None   D25E, V31I, L101I, T112V, T124A, T125A, K136Q, E152*, G163V, T218I, L234IC
 ETH-G-5568ETH-G-5568KF959748None   D25E, V31I, L101I, T112V, T124A, T125A, K136Q, G163V, A205T, T218I, L234IC
Novitsky (2015)bcpp_442bcpp_442KR860771None   S17N, D25E, L45I, M50I, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, G163V, K188R, V201I, L234I, A265VC
 mpp_213mpp_213KR860993None   D25E, V31I, F100Y, L101I, T112V, T125A, K136Q, G163V, V201I, T218I, L234I, I251L, A265VC
 bcpp_333bcpp_333KR860734None   K7Q, K14R, V31I, L45Q, I72T, F100Y, L101I, T112I, T124A, T125A, K136Q, G163V, V201I, K211R, T218I, L234I, R269KC
 bcpp_163bcpp_163KR860666None   E11D, D25E, V31I, L45Q, M50I, I60T, I72V, F100Y, L101I, T112I, T125Q, K136Q, G163V, I203M, T218I, L234I, R269KC
 bcpp_265bcpp_265KR860711None   D6E, E10D, D25E, V31I, S39R, M50I, I72V, V75I, F100Y, L101I, T112V, T125A, K136Q, G163V, V201I, K211R, T218I, L234I, A265V, R269KC
 bcpp_309bcpp_309KR860729None   V31I, K34R, M50I, F100Y, L101I, T112V, S119P, T124A, T125A, K136Q, G163V, D167E, V201I, Q216R, T218I, K219Q, L234I, D256E, A265VC