<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation G163E
Rx II-naive
IncludeMixtures No
References 11
Patients 26
Isolates 26
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Rousseau (2006)Pt3903PS073MB1DQ275649None   D6E, S17N, D25E, V31I, S39N, M50T, F100Y, L101I, T112V, T125A, K136Q, G163E, V201I, I203M, T218I, L234I, A265V, D278A, S283GC
 Pt12203SK110B1DQ056411None   S17N, D25E, V31I, L74I, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, V201I, T206S, I208M, T218I, L234I, R269K, D278A, S283GC
 Pt16204PS206B1DQ164126None   S17N, D25E, V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, H183R, V201I, I204V, T218I, L234I, D278A, S283GC
Brennan (2007)01GOB04101GOB041EF150628None   D25E, M50I, I60M, L101I, T112V, T122I, T124N, K136Q, G163E, G193E, V201I, T218I, L234I, I251L, A265V, R269K, D278AC
Matthews (2008)PS073PS073FJ199653None   D6E, S17N, D25E, V31I, S39N, M50T, F100Y, L101I, T112V, T125A, K136Q, G163E, V201I, I203M, T218I, L234I, A265V, D278A, S283GC
 PS206PS206FJ199762None   S17N, D25E, V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, H183R, V201I, I204V, T218I, L234I, D278A, S283GC
 SK011SK011FJ199850None   D25E, L45V, E48V, M50I, I73L, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, V176I, V201I, L234I, D278A, S283G, E287GC
 SK110SK110FJ199897None   S17N, D25E, V31I, L74I, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, V201I, T206S, I208M, T218I, L234I, R269K, D278A, S283GC
 SK173SK173FJ199944None   D25E, V31I, L45V, M50I, L74P, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, V201I, T206A, K215Q, L234I, D278A, S283G, D288NC
Garrido (2009)397INT-397GU217244None   K14R, S24N, D25E, V31I, V88I, L101I, T112I, T124N, T125A, K136Q, G163E, A169S, N222K, L234IC
Passaes (2009)BR.RS.RGS09BR.RS.RGS09HM026800None   R20K, V31I, M50T, L101I, T112V, T124N, K136Q, G163E, K211R, T218I, L234I, I251L, R269K, D278A, V281MC
Fish (2010)FV2605ZAFV26GQ872533None   K14R, D25E, V31I, I84M, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, V201I, K215N, L234I, S255G, R269K, D278A, S283GC
Brenner (2011)91469146HQ207790None   S17N, D25E, V31I, L45V, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, V201I, Q216R, T218I, K219Q, L234I, R269RK, D278A, S283GC
 96399639HQ207800None   S17N, D25E, V31I, L45V, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, V201I, Q216R, T218I, K219Q, L234I, R269RK, D278A, S283GC
Oliveira (2012)GD58GD58JQ670843None   V31I, M50I, L74I, F100Y, L101I, T112V, T125A, K136Q, G163E, K188R, V201I, K215N, T218I, L234I, A265V, R269K, D278A, S283G, D288NC
Zeng (2012)CN0896CN0896JQ028291None T66A S17N, R20K, V31I, L101I, T112I, T124A, T125A, K136Q, F139S, G163E, K211R, T218I, L234I, R269G, D278A, S283GC
Bessong (2013)08MB12ZA08MB12ZAHM569300None   K7R, K14R, D25E, V31I, M50I, D55N, L101I, T112I, T124A, T125A, K136Q, G163E, V201I, T206S, T218L, L234I, D278A, S283G, D288NC
 08MB18ZA08MB18ZAHM569305None   K14R, D25E, V31I, M50I, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, V201I, T218I, L234I, D278A, S283GC
 08MB22ZA08MB22ZAHM569308None   S24N, D25E, M50I, I72V, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, V201I, L234I, D270E, D278A, S283GC
 08MB63ZA08MB63ZAHM569331None   K14R, V31I, L45Q, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, H171L, V201I, L234I, D278A, V281M, S283G, R284G, D286NC
 08MB64ZA08MB64ZAHM569332None   K14R, V31I, L45Q, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, H171L, V201I, L234I, D278A, V281M, S283G, R284G, D286NC
 08MB78ZA08MB78ZAHM569343None   K14R, D25E, V31I, M50I, L101I, T112V, T124A, K136Q, G163E, V201I, T218L, L234I, R269K, D278A, V281M, S283G, R284G, D288NC
 08BBVCT50ZA08BBVCT50ZAHM569348None   S17N, V31I, M50I, L74I, I84M, F100Y, L101I, T112V, S119T, T124A, T125A, G163EC
Reigadas (2013)650650JX425859None   S24K, D25E, V31I, V32I, L45IV, L101I, T112V, S119P, T124N, T125TA, V126VM, I135IV, K136Q, G163E, K188R, S195C, V201I, K215N, Q216N, T218L, L234I, I251IV, D278AC
 654654JX425863None   S24K, D25E, V31I, V32I, L45V, L101I, T112V, S119P, T124N, K136Q, G163E, K188R, S195C, V201I, K215N, Q216N, T218L, L234I, I251V, D278AC
 4140741407JX451942None   S24N, D25E, V31I, F100Y, L101I, T112V, T124N, T125A, G163E, K188R, V201I, K215N, T218L, L234I, D278AC