<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation E157Q
Rx II-naive
IncludeMixtures No
References 5
Patients 10
Isolates 10
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Matthews (2008)PS013PS013FJ199595None   K14R, D25E, V31I, M50L, V54A, F100Y, L101I, T112V, T124A, T125A, K136Q, E157Q, K188R, V201I, K215N, T218I, L234I, A265V, R269K, D278A, S283GC
 PS131PS131FJ199702None   D25E, V31I, F100Y, L101I, T112V, T125A, E157Q, K160Q, V201I, K215N, Y227F, L234I, S255K, A265V, K273Q, D278A, S283GC
Fish (2010)P3409ZAP34GQ872492None   K14R, D25E, V31I, L101I, T112V, T124N, T125S, K156N, E157Q, G193D, S195C, V201I, L234I, A265V, R269K, D278A, S283GC
 P5109ZAP51GQ872505None   E11D, D25E, V31I, V37I, M50I, I72V, A91G, L101I, T124A, T125A, K136Q, E157Q, K160Q, D167E, V201I, K211T, L234I, A265V, R269K, D278A, R284G, D286NC
Brenner (2011)67406740HQ207738None  Q95KE11D, R20K, D25E, V31I, V37I, M50MI, I60V, K71Q, A91E, F100Y, L101I, T112V, S119R, T125A, K136Q, E157Q, K160Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A, S283GC
 73357335HQ207756None  Q95KE11D, R20K, D25E, V31I, V37I, M50MI, I60V, K71Q, A91E, F100Y, L101I, T112V, S119R, T125A, K136Q, E157Q, K160Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A, S283GC
 93299329HQ207792None   S17N, D25E, V31I, S39SN, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136HQ, M154I, E157Q, K160Q, K188KR, V201I, Q216QH, L234I, D253E, D256E, A265AITV, R269K, D278A, S283GC
 95749574HQ207795None  Q95KE11D, R20K, D25E, V31I, V37I, M50MI, I60V, K71Q, A91E, F100Y, L101I, T112V, S119R, T125A, K136Q, E157Q, K160Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A, S283GC
Monleau (2012)102-1118102-1118JQ250557None   E10D, D25E, V31I, F100Y, L101I, T112V, T124S, T125A, K136Q, K156KN, E157Q, K160KQ, K173R, K188R, A196P, V201I, T218I, L234I, R269K, D278A, E287DC
Oliveira (2012)GB44GB44JQ670832None   E11D, R20K, S24N, D25E, V31I, M50MI, I84M, Q95H, L101V, T112V, T125A, K136Q, E157Q, K160Q, V201I, N222H, L234I, D278A, S283G, R284GC