<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation Y143H
Rx II-naive
IncludeMixtures No
References 2
Patients 6
Isolates 6
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Rousseau (2006)Pt12503SK113B1DQ351237None Y143H D25E, V31I, M50I, I84M, F100Y, L101I, T112V, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A, S283GC
 Pt18004SK137B1DQ164105None Y143H K14R, A21S, D25E, V31I, K34R, E96G, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, L234I, D279G, S283GC
 Pt2461197MBAY463234None Y143H D25E, V31I, Q53R, L74I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278AC
Matthews (2008)11971197FJ199551None Y143H D25E, V31I, Q53R, L74I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278AC
 SK113SK113FJ199900None Y143H D25E, V31I, M50I, I84M, F100Y, L101I, T112V, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A, S283GC
 SK137SK137FJ199914None Y143H K14R, A21S, D25E, V31I, K34R, E96G, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, L234I, D279G, S283GC