<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation T125Q
Rx II-naive
IncludeMixtures No
References 7
Patients 9
Isolates 9
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Matthews (2008)SK085SK085FJ199886None   K7R, D25E, V31I, M50T, I72V, L74I, F100Y, L101I, T112V, S119P, T124A, T125Q, K136Q, F181S, V201I, T218I, K219Q, L234I, D278A, D286NC
Garrido (2009)409INT-409GU217256None   S17T, D25E, V31I, I84M, F100Y, L101I, T112V, T125Q, K136Q, V201I, L234I, V281VM, S283GC
Monleau (2012)102-1074102-1074JQ250556None   E13D, V31I, M50MI, C56S, I84M, P90PS, L101I, T112V, S119R, T124S, T125Q, K136Q, V201I, I203IM, K211R, T218I, L234I, A265V, R269K, D278AC
Oliveira (2012)GA11GA11JQ670798None   S17N, D25E, V31I, M50I, L63I, I72IV, L74I, F100Y, L101I, T112V, T124TA, T125Q, K136Q, V201I, T218L, L234I, A265V, R269K, D278A, S283DGC
Bessong (2013)08BBVCT0608BBVCT06HM569272None   D25E, I84M, L101I, T112V, T124A, T125Q, K136Q, V201I, L234I, S283G, R284G, D288NC
 08MB61ZA08MB61ZAHM569329None   S17N, D25E, V31I, M50V, F100Y, L101I, G106A, T112V, T124A, T125Q, K136Q, V201I, T218I, L234I, A265V, R269K, D278A, S283GC
Novitsky (2015)bcpp_163bcpp_163KR860666None   E11D, D25E, V31I, L45Q, M50I, I60T, I72V, F100Y, L101I, T112I, T125Q, K136Q, G163V, I203M, T218I, L234I, R269KC
 mpp_340mpp_340KR861111None  G163KD6E, E10D, D25E, V31I, M50I, I72V, L74I, I84L, I89L, P90T, F100Y, L101I, T112V, T125Q, K136Q, K188R, V201I, K211R, T218I, L234I, A265VC
Billings (2016)CO3168V4CO3168V4KX907366None   V31I, M50I, I72V, Q95H, F100Y, L101I, T112V, T124A, T125Q, K136Q, V201I, L234I, R269K, D278A, V281M, S283GC