<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation T97A
Rx II-naive
IncludeMixtures No
References 18
Patients 31
Isolates 31
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Brennan (2007)01BAB09401BAB094EF150565None  T97AD6N, K7E, S39C, M50I, L74I, A91E, L101I, S119R, T125AB
 01BAB09801BAB098EF150623None  T97AD6E, E10D, L45V, M50I, I72V, I84L, A91T, L101I, S119R, T124A, T125A, V201I, T218SB
Sa-Filho (2007)BREPM1027BREPM1027EF637054None  T97A, V151ID6T, K7E, E11D, E13D, V31I, M50T, I72V, L101I, K156RB
Brumme (2009)INT_3639INT_3639FJ813090None  T97AE11ED, V31I, I72IV, L101I, K103R, K111T, S119T, T125A, V126T, D167DE, V201I, T206S, I208L, E212A, T218TS, S230N, D232EB
 INT_3986INT_3986FJ813437None  T97AE11D, V31I, I72V, I84IM, L101I, K103R, K111T, S119T, T125A, V126T, V201I, T206S, I208L, E212A, T218S, S230N, D232EB
 Q4546Q4546GQ372111None  T97A, P145PLA91E, L101I, G106A, T112TA, S119R, T124AD, I135V, I203M, I208L, K211R, E212IK, D256E, S283GB
 R1522R1522GQ372125None  L74M, T97AD6E, V77VA, A91E, V110VI, T112I, S119R, T124N, T125A, V126L, G163AST, S230N, R262RK, I267IF, D270DNB
 X6521X6521GQ372260None  T97AR20K, V31I, L101I, K111T, T125A, Q137H, V201I, D207N, K211N, T218S, K219N, N222KB
 Z0528Z0528GQ372296None  T97AV31I, M50I, G163A, K211R, S230NB
Low (2009)ahi104ahi104_04FJ786372None  T97AE11D, R20K, M22L, V37I, S39C, I72V, L101I, K111T, I113V, T122I, T124A, T125A, V201I, K211R, S283GB
Sanabani (2011)BR1115BR1115JN692479None  T97AV31I, S119T, T124N, T125A, V126L, I141V, I203M, D256EB
Armenia (2012)PT_12PT_12_BLJN544084None  T97AL101I, S283GB
Garrido (2012)BAA295937BAA295937JQ716912None  T97AE11D, S24G, D25E, L45V, M50I, L101I, T125A, F181L, T206S, D256E, S283G, D288NB
Iamarino (2012)B.BR.1239B.BR.1239JN234134None  T97A, V151IE11D, S17C, M50I, I72V, L101I, K211RB
Molina (2012)41734173_1 None  T97AK14R, R20K, V31I, V32VA, A33AT, L101I, T112IV, T124A, T125A, G134N, I135V, G163Q, G193E, V201I, T206S, T218TI, Y227F, L234I, S255N, D256E, D279G, S283GB
Rolland (2012)AA040a_WG13AA040a_WG13JX447158None E138KT97AG70E, L101I, S119R, T124N, T125S, M154I, K211RB
Sax (2012)63886388_1 None  T97AE11D, V31I, M50MT, G70E, L101I, T112I, S119R, T124N, D167E, V201I, T206S, I208L, E212A, T218S, K240KR, S255N, D256E, R284GB
Li (2013)hnxy27hnxy27KC988074None  T97AV88I, A91T, L101I, K111R, S119R, T124N, T125S, K156N, K188R, K211RB
Reigadas (2013)123123JX425591None  T97AE69EV, A91E, L101I, S119R, T122I, T124S, T125A, F181L, V201I, L234I, V281LB
 129129JX425597None  T97AV31I, T93S, L101I, T124A, K156N, G163Q, V201I, D279G, D286NB
 143143JX425611None  V54I, T97AK14R, R20K, A21T, A23V, M50I, L101I, K160T, V201I, I203M, I204V, V281MB
 144144JX425612None  T97AE11D, V31I, K34R, L101I, T112V, T125V, K215N, D256EB
Hachiya (2015)D9373D9373LC022716None N155HT97A, V151ID25DE, D41DN, S119G, T122I, T125A, V201I, K215N, Q221S, N222K, D256E, R269KB
Pessoa (2015)10BR_MG007MG007KJ849786None  T97AE10D, V31I, L45V, M50I, Q53R, L74I, L101I, S119T, E157Q, G163E, I200T, V201I, K211R, S255N, D256E, R269KB
Pessoa (2016)10BR_RJ01210BR_RJ012KT427649None  T97AK14R, I72V, T125A, V126M, K127R, V201I, D256E, S283GB
 10BR_SP00410BR_SP004KT427829None  T97AA23S, S24G, S39C, L45I, M50I, I72V, L101I, T124N, T125A, I135V, K156N, I203M, I208L, R231K, S255R, S283GB
Chen (2017)219511881219511881KY574954None  T97AS17N, A91E, L101I, T112I, S119R, T124N, K156N, V201IB
 248000813248000813KY369934None  T97AE10D, V31I, A49P, K71Q, P90A, L101I, S119R, K156N, E157Q, V201I, K236X, D256EB
 218512194218512194KY434644None  T97AV31I, L101I, I135V, K156N, K219N, N222KB
Hachiya (2017)C13-2095GM3994LC160550LC160550None  T97AE11D, V31I, S39C, S57N, L101I, S119P, I135V, K136Q, V201I, T206S, K215NB
 C13-51111539LC160796LC160796None  T97AE11D, V31I, S39C, S57N, L101I, S119T, T124A, I135V, K136Q, V201I, T206S, K215NB