<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation T97A
Rx >=1 INI
IncludeMixtures No
References 14
Patients 93
Isolates 111
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Malet (2008)H6H6-W20FJ538984RAL20N155HT97A, V151IE11D, V31I, L101I, K111T, I113V, S119T, T124N, T125A, S195C, A196P, A205T, T218S, D232NB
Canducci (2009)pt6pt6w20EU908751RAL21E138AT97A, Y143KL101I, S119R, K156N, I208LB
  pt6W24EU908752RAL26E138EA, G140GS, Q148QHT97A, Y143Y*KNL101I, S119SR, K156N, I208LB
  pt6W36EU908753RAL39G140S, Q148HT97AL101I, S119R, K156N, I208LB
 pt4pt4W24EU908762RAL26Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  pt4w32EU908763RAL35Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211KR, D256EB
  pt4w36EU908764RAL39Y143CL74M, T97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211R, D256EB
 pt5pt5w48EU908777RAL52 T97A, Y143S, S230RK14R, M22L, V32I, V37I, S39C, L101I, G163Q, V201I, D253EB
Garrido (2009)Pt03Pt03 RAL Y143RT97AH12HN, V31I, K111T, S119T, T125A, V126L, I135V, P142A, I203M, I208L, D256EB
Sichtig (2009)Pt014786FJ183692RAL47Y143RL74M, T97AE11D, R20K, V31I, H51HR, S119G, T122I, T125A, V201I, K215NB
 Pt105150FJ183702RAL106Y143RL74M, T97A, E138DS17N, M22I, A23V, L28I, L45V, L101I, S119T, T218TS, L234LV, D256E, I268MB
Hatano (2010)4Virus15GU121691RAL Y143RT97AK7R, S17N, V31I, L101I, T112A, T125A, M154I, V201IB
  Virus16GU121692RAL Y143RT97A, G163GRK7R, S17N, V31I, L101I, T112A, S119T, T125A, M154I, V201VIB
 12Virus101GU121777RAL Y143YCT97A, S230RG4GR, R20K, T112V, I113V, T125A, H171Q, Y194YH, I200M, I203MB
Blanco (2011)CA1556CA124202 RAL85Y143CL74M, T97A, S230RK7R, S17N, L101I, K111Q, T112K, S119R, T206S, K211R, D256EB
Brenner (2011)102001.076102001.076HQ423441RAL T66IT97A, G163RE11D, D25E, V31I, I60V, I72V, A91T, G106A, T112I, I113V, S119P, T124N, T125V, I203M, A205T, D256E, D278DYB
 1109011090HQ423447RAL  T97AE11D, N27S, V31I, L101I, K111T, I113V, S119P, T124N, K211N, D232E, D286NB
Canducci (2011)Pt1Pt1W20JN163877RAL21E138AT97A, Y143KH16P, M22R, L101I, S119R, K156N, I208LB
  Pt1W24JN163878RAL26G140S, Q148HT97AL101I, S119R, K156N, I161F, I208LB
 Pt2Pt2W24JN163881RAL26Y143CT97AL101I, S119R, T124N, T125A, M154L, V165I, D256E, G277CB
  Pt2W36JN163882RAL35 L74M, T97A, Y143GL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277CB
  Pt2W37JN163883RAL36 L74M, T97A, Y143GI36V, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  Pt2W56JN163884RAL55Y143RT97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277RB
  Pt2W64JN163885RAL64E138A, Y143CL74M, T97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G272E, G277RB
 Pt5Pt5W48JN163892RAL52 T97A, Y143S, S230RQ9H, K14R, A23G, V32I, V37I, L101I, G163Q, V201I, D253EB
 Pt6Pt6W32JN163895RAL28Y143RT97AS17N, V31I, L101I, T112I, S119P, T122I, T124N, T206S, T218S, Y227F, D256EB
Armenia (2012)PT_12PT_12_MO_1JN544085RAL Y143RT97AL101I, S283G, D286DNB
  PT_12_MO_3JN544086RAL Y143RT97AL101I, S283G, D286DNB
  PT_12_MO_7JN544087RAL Y143RT97AL101I, T112TA, S119ST, S283GB
  PT_12_MO_9JN544088RAL Y143RT97AD3DN, D25DE, L101I, T112TA, S119ST, S283GB
Molina (2012)32693269_4 EVG58 T97AS39C, M50I, L101I, S119P, M154L, V201I, T206S, T218SB
 31243124_2 EVG40 T97AK14R, R20RK, A91E, L101I, S119R, T124N, G193D, V201I, T206S, I208IL, I268L, D279GB
  3124_3 EVG47 T97AK14R, R20RK, A91E, L101I, S119R, T124N, G193D, V201I, T206S, I208IL, I268L, D279GB
  3124_4 EVG95 T97AK14R, A91E, L101I, T112A, S119R, T124N, G193D, V201I, T206S, I208L, L234LF, I268L, R269RK, D279GB
 33893389_3 RAL106 L74LM, T97A, V151VID6E, E10D, A91S, K103KR, S119G, T122I, T124A, T125A, I220L, Y227F, L234IB
 41734173_2 EVG43 T97AK14R, R20K, V31I, L101I, T112IV, T124A, T125A, G134N, I135V, G163Q, G193E, V201I, T206S, T218TI, Y227YF, L234I, S255N, D256E, D279G, S283GB
 40104010_2 RAL25 L74M, T97AD6DN, E10D, S39SG, M50I, L101I, T112I, S119P, T124A, T125A, I135L, T206S, D279NB
Souza Cavalcanti (2012)BRSPBR10SP267CJQ797720RAL74F121YT97A, V151IE11D, K14R, S24D, L28I, S39C, I72V, L74I, S119P, Q137H, Q164K, R187K, V201I, D232E, L234FB
  BR11SP363BJQ797725RAL135Y143RT97AE11D, E13X, K14R, S24D, L28I, S39C, K42KR, L74I, S119P, Q164K, R187K, V201I, D232E, L234IB
de Souza Cavalcanti (2014)BRSP332BRSP332 RAL N155HT97A, V151I, G163RS17N, V31I, I72V, S119R, T124A, T125V, K156N, V165I, Q168R, V201I, R224Q, D256E, R269K, V281M, S283GB
 BRSP94BRSP94 RAL N155HT97A, V151ID6E, E10D, A21S, A23V, S39R, M50I, L101I, S119P, T122I, K156R, A169V, S230N, L234I, S283NB
 BRSP08BRSP08 RAL  L74M, T97A, V151I, G163RK14R, V31I, I72A, L101I, I113L, S119G, T122I, T124TN, K156KN, E157Q, V201I, T206S, S283GB
 BRSP287BRSP287 RAL G140S, Q148HT97AK14KR, R20K, G70E, L101I, T112V, S119R, T124S, T125A, V201I, D232NB
 BRSP37BRSP37 RAL N155HT97A, V151IS17N, A21S, D25E, L28I, S39C, L101I, S119R, T218SB
 BRSP222BRSP222 RAL Y143RL74M, T97A, E138DE10D, V31I, M50I, L101I, T112V, S119P, T122I, T124N, T125A, I135V, E157Q, I203M, I208L, T218S, I220L, D253VB
 BRSP10BRSP10 RAL  T97A, V151IS17N, S24A, G59E, I60L, I72V, L101I, T112V, T124N, T125AB
 BRSP74BRSP74 RAL E138A, G140S, Q148HT97AS17N, I72V, L101I, S119R, K156N, K188R, V201I, K211R, I268L, D270NB
 BRSP267BRSP267 RAL F121YT97A, V151IE11D, K14R, S24D, L28I, S39C, I72V, L74I, S119P, Q137H, Q164K, R187K, V201I, D232E, L234FB
 BRSP95BRSP95 RAL N155HT97A, V151ID6N, K7E, M50I, L101I, S119P, V201I, T206S, I208L, K211R, E212L, D232NB
 BRSP527BRSP527 RAL  T97AK14R, L101I, S119T, T124A, P142T, I208L, K211R, E212L, N254Q, S255G, R284GB
Hardy (2014)Pt1INTPt1INT RAL, DTG110E138K, S147G, N155HT97A, V151ID6DN, R20RK, V31I, L45I, L101I, S119R, I135V, E157Q, K160Q, V201I, K215NB
  Pt1INT RAL, DTG157E138K, S147G, N155HT97A, V151IR20K, V31I, L45I, A49P, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB
  Pt1INT RAL, DTG168E138K, S147G, N155HT97A, V151IR20RK, V31I, L45I, A49P, L68LF, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB
Hurt (2014)IN_1019IN_1019 RAL T66TI, N155HL74M, T97A, V151ID6E, S17N, M50I, I72V, L101LI, S119R, K156N, V201VI, I208M, E212AB
 IN_883IN_883 RAL E92QT97A, V151IS17N, L28I, A49P, I72IV, K111R, S119T, T124A, T125A, V165VIB
 IN_321IN_321 RAL G140S, Q148HT97AE11D, V31I, I72IV, T112TI, S119P, T122I, T125A, V126VL, G163GV, V201I, N254Q, S255GB
 IN_2589IN_2589 RAL Y143CT97A, S230RK14R, L63LI, L74I, L101I, S119ST, G134GE, D167E, I208L, K211QB
 IN_2414IN_2414 RAL Y143CV54I, T97A, S230RS17N, V31VI, L74I, L101I, T112A, S119T, T124A, R187K, K188R, K211R, D256EB
 IN_954IN_954 RAL Y143RL74M, Q95K, T97AD6E, E10D, S17T, A23V, A91T, L101I, S119P, T122I, T124A, T125AB
 IN_1160IN_1160 RAL  L74M, T97A, Y143AS, S230RS17N, V31I, K34R, S39R, S119T, T124A, T206S, D229EB
 IN_3146IN_3146 RAL Y143CT97A, S230RK14R, V31I, Q95AT, L101I, S119T, T124A, V201IB
 IN_1459IN_1459 RAL N155HT97AS17N, M50MV, L101I, K111R, T112I, S119R, T124G, T125A, V165I, E198D, V201I, I220L, Y227F, D256E, D278DNB
 IN_1881IN_1881 RAL Y143RT97AV32I, D41N, I72V, V126M, T206SB
 IN_668IN_668 RAL Y143CT97A, G163R, S230RS17N, T124A, T125A, K211Q, S283SGB
 IN_800IN_800 RAL Y143RL74M, T97AS17N, S119T, E157Q, K160Q, V201I, D256E, R284GB
 IN_508IN_508 RAL  L74M, T97A, Y143S, S230RS17N, V31VI, K34R, S39R, S119T, T124A, I204IV, T206S, D229EB
 IN_1391IN_1391 RAL Y143CT97A, S230RK14R, V31I, Q95A, L101I, S119T, T124A, M154L, V201IB
 IN_1752IN_1752 RAL E138K, Y143CL74M, T97A, A128T, S230RE13D, K14KR, S17N, V31I, L63LI, L101I, T112A, S119R, K156N, I208L, Q252K, D288NB
 IN_212IN_212 RAL Y143RL74M, T97AS17N, R20K, V31I, T112S, I113V, S119ST, T124S, T125A, E157Q, K160Q, V201I, K211R, R284GB
 IN_1642IN_1642 RAL Y143RL74M, T97AS17N, L101I, S119G, T122I, T124A, T125A, L234V, V259IB
 IN_1518IN_1518 RAL Y143RT97AD6E, S17N, V31I, L101I, S119T, T124TN, T206S, D232EB
 IN_1564IN_1564 RAL  L74M, T97A, Y143G, G163GRS17N, S39N, L101I, T112A, S119R, T124A, T125A, I135V, Y194L, S195H, A196T, K211KR, S230SN, I268L, D270H, R284RGB
 IN_3316IN_3316 RAL Y143RL74LM, T97AM22I, L28M, V31VI, V32I, I60IM, L101I, S119P, T122TI, T124N, G163V, Q216N, Q221RB
 IN_439IN_439 RAL N155HT97AS17N, S39C, M50I, T112V, I113V, S119R, T124N, T206SB
 IN_2493IN_2493 RAL Y143CL74M, T97A, S230RS17N, V31I, D41N, L63I, L101I, S119R, T124A, G163T, T218S, K219N, N222K, D229DG, S283GB
 IN_3088IN_3088 RAL Y143YCHRT97AE11D, V31VI, V32I, V37I, D41N, I60M, I72IN, L101I, G106A, K111T, S119R, T122I, H171HQ, V201IB
 IN_2231IN_2231 RAL  T97A, Y143GE11D, V31I, V32I, V37I, L63I, I72IV, L74I, L101I, T112TK, T115S, S119R, T124TN, V201I, S230NB
 IN_1795IN_1795 RAL Y143CT97A, G163GR, S230RS17N, R20RK, V31I, A80S, L101I, S119T, T124A, T125A, T206S, D256E, S283GB
 IN_1569IN_1569 RAL  L68V, L74M, E92L, T97AK34R, M50I, V88VI, T112TA, T125A, V201I, T218S, S230NB
 IN_1789IN_1789 RAL Y143RT97A, G163RS24N, S119P, T125A, I135V, T206S, T210I, S283GB
 IN_2021IN_2021 RAL Y143RT97AV31I, I60M, L74I, T112I, T124A, T125A, V126M, E157Q, K160Q, F181L, T206S, N254QB
 IN_214IN_214 RAL Y143RL74M, Q95QK, T97AE10D, V31I, L101I, T112A, S119T, T124A, T125A, I135VB
 IN_1321IN_1321 RAL Y143RL74IM, T97AK14KR, S17N, T112A, S119T, T124A, T125A, A128PS, V201IB
 IN_266IN_266 RAL Y143RL68V, L74M, T97AV31I, L101I, S119T, G163Q, F181L, T206SB
 IN_1599IN_1599 RAL Y143RL74M, Q95QK, T97AE11D, V31I, I72V, I113V, S119T, T124A, T125TA, F181L, V201I, A205S, T206S, D207E, K211R, K219N, N222KB
 IN_1362IN_1362 RAL Y143YC, N155NHT97AK7R, E11D, R20RK, M50I, P90PS, L101I, T112I, S119R, R187K, K188R, G193E, T218S, N222K, R269K, D288NB
 IN_1656IN_1656 RAL Y143RT97A, G163RE11D, S24N, D25E, V31I, L101I, K111R, T112A, S119P, T122I, T125A, R187K, I220L, K240KRB
 IN_929IN_929 RAL Y143RT97AE11D, D25E, V31I, L101I, K111T, S119P, T122IB
 IN_2012IN_2012 RAL Y143RT97A, G163EKK7Q, E10A, E11D, K14R, V31I, L45V, L101I, T125A, E170EQ, G193R, V201I, I208M, E212A, Q216H, K219Q, S230N, D256EB
 IN_758IN_758 RAL Y143RT97AV31I, L74I, T112I, T124A, T125A, V126M, E157Q, K160Q, F181L, T206S, N254Q, S255SG, V259VI, S283SGB
 IN_2205IN_2205 RAL Y143RT97AK7R, S39C, I72V, L101I, T124A, V201I, Q216H, Q221NB
 IN_2785IN_2785 RAL E92QT97A, V151IE11D, K14R, S24N, D41DN, L63I, L74I, L101I, T112S, T125A, G163E, V201I, I208M, L234V, D279GB
 IN_341IN_341 RAL E92QL68V, L74M, T97AE10D, V31I, M50I, I73V, E96D, L101I, S119T, T124N, T125A, I135V, E157Q, K160T, I208M, S230N, D232E, L234F, D253E, D256E, E287EAB
 IN_2058IN_2058 RAL N155HT97A, V151IR20K, M50IT, I72V, L101I, S119R, T124A, G193E, K211R, L234LV, D278A, D286NB
 IN_3198IN_3198 RAL E92QT97AD6E, E10D, V31I, L101I, S119G, T122I, T124N, G163EB
 IN_2250IN_2250 RAL Y143CT97A, S230RS17N, C56CR, I72V, F100Y, L101I, K111T, I113L, T124R, T125A, I203M, T206S, I208L, E212L, T218SB
 IN_1608IN_1608 RAL E138EK, Y143RL74M, T97AK14R, S17N, A23V, L28I, P30A, S39C, Q95QR, L101I, T112V, S119G, T122I, T125Q, V201I, T206S, K240R, V259VIB
 IN_1804IN_1804 RAL Y143RT97A, A128TE11D, S24N, D25E, V31I, L45V, T112TA, S119P, G163T, K211RB
 IN_1514IN_1514 RAL Y143RL74LM, T97A, G163KV31I, L45I, A49P, L101I, S119SG, T122TI, V201I, K215NB
 IN_787IN_787 RAL E92QL68V, L74M, T97AE10D, V31I, M50I, I73V, E96D, L101I, S119T, T124N, T125A, I135V, E157Q, K160KPQT, I208M, S230N, D232E, L234F, D253E, D256EB
 IN_487IN_487 RAL Y143RL74M, Q95QK, T97AE10D, V31I, L63LI, L101I, T112A, S119T, T124A, T125A, I135VB
 IN_119IN_119 RAL  T97A, Y143SS17N, V31I, M50I, L74I, L101I, K111R, S119R, T124N, I135V, K188R, S230N, K264RB
 IN_1513IN_1513 RAL Y143RL74LM, T97A, E138ED, G163KV31I, L45I, A49P, L101I, S119SG, T122TI, V201I, K215NB
 IN_1251IN_1251 RAL Y143RT97AE11D, V31I, L101I, K111N, S119P, G163T, L234I, D253DH, S283SDGNB
 IN_2470IN_2470 RAL Y143CT97A, V151ID6DE, K14KR, A21AT, M50I, L101I, S119R, L234VB
 IN_2519IN_2519 RAL Y143HL74M, T97A, G163RE11D, K14R, A21T, S24G, D25E, S39C, L45V, L101I, S119G, T122I, T125A, E170EG, T206TS, Q216H, S283SNB
 IN_1380IN_1380 RAL N155HT97A, V151VIK7R, V31I, M50I, T112TI, S119SR, K156N, V201I, L234IB
 IN_1820IN_1820 RAL Y143CL74M, T97A, G163R, S230RL63LV, S119T, T124A, I203IM, K211KRB
 IN_2186IN_2186 RAL Y143RT97AK7R, M50V, I72V, L74I, L101I, S119P, I135V, G163GE, H171QB
 IN_1405IN_1405 RAL N155HT97A, V151I, G163RE11D, S17T, V31I, V79I, L101I, S119P, I135V, F181L, V201I, T206SB
 IN_332IN_332 RAL Y143RT97A, E138DE11D, S17C, L101I, K111KR, T112K, S119G, T122I, T124TN, T125A, T218SB