<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation T97A
Rx >=1 INI
IncludeMixtures No
References 10
Patients 18
Isolates 32
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Malet (2008)H6H6-W20FJ538984RAL20N155HT97A, V151IE11D, V31I, L101I, K111T, I113V, S119T, T124N, T125A, S195C, A196P, A205T, T218S, D232NB
Canducci (2009)pt6pt6w20EU908751RAL21E138AT97A, Y143KL101I, S119R, K156N, I208LB
  pt6W24EU908752RAL26E138EA, G140GS, Q148QHT97A, Y143Y*KNL101I, S119SR, K156N, I208LB
  pt6W36EU908753RAL39G140S, Q148HT97AL101I, S119R, K156N, I208LB
 pt4pt4W24EU908762RAL26Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  pt4w32EU908763RAL35Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211KR, D256EB
  pt4w36EU908764RAL39Y143CL74M, T97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211R, D256EB
 pt5pt5w48EU908777RAL52 T97A, Y143S, S230RK14R, M22L, V32I, V37I, S39C, L101I, G163Q, V201I, D253EB
Garrido (2009)Pt03Pt03 RAL Y143RT97AH12HN, V31I, K111T, S119T, T125A, V126L, I135V, P142A, I203M, I208L, D256EB
Sichtig (2009)Pt014786FJ183692RAL47Y143RL74M, T97AE11D, R20K, V31I, H51HR, S119G, T122I, T125A, V201I, K215NB
 Pt105150FJ183702RAL106Y143RL74M, T97A, E138DS17N, M22I, A23V, L28I, L45V, L101I, S119T, T218TS, L234LV, D256E, I268MB
Hatano (2010)4Virus15GU121691RAL Y143RT97AK7R, S17N, V31I, L101I, T112A, T125A, M154I, V201IB
  Virus16GU121692RAL Y143RT97A, G163GRK7R, S17N, V31I, L101I, T112A, S119T, T125A, M154I, V201VIB
 12Virus101GU121777RAL Y143YCT97A, S230RG4GR, R20K, T112V, I113V, T125A, H171Q, Y194YH, I200M, I203MB
Blanco (2011)CA1556CA124202 RAL85Y143CL74M, T97A, S230RK7R, S17N, L101I, K111Q, T112K, S119R, T206S, K211R, D256EB
Brenner (2011)102001.076102001.076HQ423441RAL T66IT97A, G163RE11D, D25E, V31I, I60V, I72V, A91T, G106A, T112I, I113V, S119P, T124N, T125V, I203M, A205T, D256E, D278DYB
 1109011090HQ423447RAL  T97AE11D, N27S, V31I, L101I, K111T, I113V, S119P, T124N, K211N, D232E, D286NB
Canducci (2011)Pt1Pt1W20JN163877RAL21E138AT97A, Y143KH16P, M22R, L101I, S119R, K156N, I208LB
  Pt1W24JN163878RAL26G140S, Q148HT97AL101I, S119R, K156N, I161F, I208LB
 Pt2Pt2W24JN163881RAL26Y143CT97AL101I, S119R, T124N, T125A, M154L, V165I, D256E, G277CB
  Pt2W36JN163882RAL35 L74M, T97A, Y143GL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277CB
  Pt2W37JN163883RAL36 L74M, T97A, Y143GI36V, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  Pt2W56JN163884RAL55Y143RT97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277RB
  Pt2W64JN163885RAL64E138A, Y143CL74M, T97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G272E, G277RB
 Pt5Pt5W48JN163892RAL52 T97A, Y143S, S230RQ9H, K14R, A23G, V32I, V37I, L101I, G163Q, V201I, D253EB
 Pt6Pt6W32JN163895RAL28Y143RT97AS17N, V31I, L101I, T112I, S119P, T122I, T124N, T206S, T218S, Y227F, D256EB
Armenia (2012)PT_12PT_12_MO_1JN544085RAL Y143RT97AL101I, S283G, D286DNB
  PT_12_MO_3JN544086RAL Y143RT97AL101I, S283G, D286DNB
  PT_12_MO_7JN544087RAL Y143RT97AL101I, T112TA, S119ST, S283GB
  PT_12_MO_9JN544088RAL Y143RT97AD3DN, D25DE, L101I, T112TA, S119ST, S283GB
Souza Cavalcanti (2012)BRSPBR10SP267CJQ797720RAL74F121YT97A, V151IE11D, K14R, S24D, L28I, S39C, I72V, L74I, S119P, Q137H, Q164K, R187K, V201I, D232E, L234FB
  BR11SP363BJQ797725RAL135Y143RT97AE11D, E13X, K14R, S24D, L28I, S39C, K42KR, L74I, S119P, Q164K, R187K, V201I, D232E, L234IB