<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation E92Q
Rx >=1 INI
IncludeMixtures No
References 7
Patients 34
Isolates 38
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Malet (2008)2dH2-W28FJ538976RAL29E92Q, N155H E11D, V31M, V32I, S39C, I72V, L101I, K111R, S119P, I135V, G193E, V201I, T218S, D288GB
 33_W14 RAL14E92Q R20K, A23V, I72V, T124A, I204V, T206SB
Hatano (2010)18Virus94GU121770EVG E92Q K7KR, D41DN, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234IB
  Virus95GU121771EVG E92Q, Q148QRL74LMK7KR, D41DN, I72IV, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234IB
  Virus97GU121773EVG E92QL68LV, L74LMK7KR, D41DN, I72IV, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234IB
 16Virus21GU121697EVG E92Q R20K, T112A, T124A, T125TMB
DeJesus (2012)74257425_2 EVG71E92Q S17N, I84L, V88VL, T124S, K156N, I203M, D256EB
Molina (2012)30563056_2 EVG19E92Q S17N, K34R, K46KR, M50L, T124A, T125A, V201I, A205S, T206S, I208L, K211RG, E212AB
  3056_3 EVG24E92QH51HYS17N, K34R, M50L, T124A, T125A, V201I, A205S, T206S, I208L, K211R, E212AB
 32833283_2 EVG31E92Q V31I, I84M, L101I, K111T, I135V, V201I, T206S, K211R, E212T, K219NB
  3283_3 EVG39E92Q V31I, I84M, L101I, K111T, I135V, V201I, T206S, K211R, E212T, K219N, A265TB
Sax (2012)66676667_2 EVG48E92Q M50I, T125A, I135V, M154I, I162V, V201I, K215N, L234IB
 60126012_2 EVG42E92QH51HY, L68VE11D, K14R, S17T, S39C, I60V, T112I, T124A, T206S, E212AB
 61826182_2 EVG25E92Q L101I, T112V, T210TI, I220V, L242LF, D253E, R284GB
 62576257_2 EVG34E92Q E11D, S17T, A23V, I73V, T124A, S153A, G189GR, G193E, V201I, I208M, E212Y, Q216H, I220LB
 66486648_2 EVG16E92Q K14R, R20K, S24N, D25E, V31I, G59E, I60V, L101I, T124A, T125A, D167DE, K215R, N222KB
de Souza Cavalcanti (2014)BRSP545BRSP545 RAL E92Q, N155H K14R, Y15H, V32I, S39C, M50I, I73IV, L101I, S119P, T124A, I135V, K136N, E157Q, K160Q, I162V, V201I, L234V, K240RB
 BRSP553BRSP553 RAL E92QL74M, V151IE10D, A21S, M50I, K211RB
 BRSP496BRSP496 RAL E92Q, N155HV151IH12Q, K14R, A21S, A23T, V31I, L101I, T124A, I204V, K215N, D279NB
 BRSP705BRSP705 RAL E92Q, N155HV151IE10D, A21SB
Hurt (2014)IN_1331IN_1331 RAL E92QL74MS39C, L45Q, L63I, I72L, Q216N, L234I, D270H, R284GB
 IN_883IN_883 RAL E92QT97A, V151IS17N, L28I, A49P, I72IV, K111R, S119T, T124A, T125A, V165VIB
 IN_443IN_443 RAL E92Q, N155HE138EDS17N, I72V, T112I, T124A, T125V, T206S, D232DN, D279DGB
 IN_20IN_20 RAL E92QV151VIK34R, D41DN, I141VB
 IN_2284IN_2284 RAL E92Q E96D, L101I, T112TA, T124TA, V201I, A205S, E212A, V281MB
 IN_501IN_501 RAL E92Q, N155HA128AT, E138ED, V151VIV31I, I72V, L101I, T125M, F181L, V201I, S230N, A265AV, I268ILB
 IN_3091IN_3091 RAL E92QL74M, E138DE11D, S24N, D25E, K211R, K215N, I220L, S230N, D256E, D278DNB
 IN_1880IN_1880 RAL E92Q, N155H S39C, L101I, T124N, I135V, F181L, V201IB
 IN_370IN_370 RAL E92Q E11ED, K14R, V31I, K111T, V201I, T218S, S230N, D256EB
 IN_827IN_827 RAL E92Q, N155H E11D, S24N, M50MI, I72V, K111R, I113V, T206S, S230N, N254Q, S255GB
 IN_144IN_144 RAL E92Q, N155HE138EDS17N, I72V, T124A, S283GB
 IN_2785IN_2785 RAL E92QT97A, V151IE11D, K14R, S24N, D41DN, L63I, L74I, L101I, T112S, T125A, G163E, V201I, I208M, L234V, D279GB
 IN_341IN_341 RAL E92QL68V, L74M, T97AE10D, V31I, M50I, I73V, E96D, L101I, S119T, T124N, T125A, I135V, E157Q, K160T, I208M, S230N, D232E, L234F, D253E, D256E, E287EAB
 IN_3198IN_3198 RAL E92QT97AD6E, E10D, V31I, L101I, S119G, T122I, T124N, G163EB
 IN_787IN_787 RAL E92QL68V, L74M, T97AE10D, V31I, M50I, I73V, E96D, L101I, S119T, T124N, T125A, I135V, E157Q, K160KPQT, I208M, S230N, D232E, L234F, D253E, D256EB
 IN_1453IN_1453 RAL E92QL74MV31I, M50I, I60M, Y99F, G106A, T112M, T124A, D167E, T206S, S230N, D256E, R269KB
 IN_928IN_928 RAL E92Q, Y143HL68VV31I, T112TA, S119T, V201I, T206S, M275MV, S283GB
 IN_126IN_126 RAL E92Q, N155H R20K, M50I, E96ED, T124A, E157Q, K160T, G193E, V201I, T218S, I220V, D256E, D279DGB