<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation L68V
Rx II-naive
IncludeMixtures No
References 11
Patients 49
Isolates 51
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Su (2003)02HNsq402HNsq4AY275555None  L68VK71Q, V88I, A91T, L101I, S119R, T122A, T124N, T125A, K156N, K211R, D286NB
Liu (2005) 02HNsq4DQ007902None  L68VK71Q, V88I, A91T, L101I, T112A, S119R, T124N, T125A, K156N, K211RB
Luk (2008)BA-04006CM-BA-040EU693240None  L68VE11D, K14R, V31I, M50L, I72IV, L101I, T112V, S119P, T122I, T124A, T125A, G134D, G163V, D167E, V201I, T206S, I208M, T218I, L234I, D256E, S283GB
Miura (2008)BEC45BEC45EU517871None  L68VE11D, S17T, M50MI, I72V, T124A, V201I, I208L, K211Q, E212EA, T218I, I251IVB
Brumme (2009)INT_3663INT_3663FJ813114None  L68VE11D, V32I, T112A, S119TB
 F5510F5510GQ371873None  L68VE11D, N27G, V31I, V32I, M50I, K111T, T124A, S195SR, V201I, T206S, K219KT, S230NB
 P3502P3502GQ372080None  L68VS17N, D41N, M50I, P90S, S119R, T124N, M154I, G163E, K211R, D256EB
Garrido (2009)95INT-95GU216942None  L68VV31I, K111T, S119T, T125A, V126L, I135V, I203M, A265E, R269RTB
 126INT-126GU216973None  L68VV31I, K111T, S119T, T125A, V126L, I135V, I203M, G245GAB
Low (2009)ahi25ahi25_96FJ786292None  L68VD6E, L28I, S39C, L45I, L101I, K156N, N254QB
 ahi51ahi51_06FJ786318None  L68VM50I, I73V, V201IB
Sichtig (2009)55925592FJ183670None  L68VK34R, I72V, I113V, T124N, T125A, G163E, I220MB
Parczewski (2012)590_1590_1KC409180None  L68VL101I, T125TA, E157Q, K160Q, K188KR, G193GR, K211R, K219T, I220L, L234I, D253E, D256E, A265AVB
Li (2013)hnxx198hnxx198KC988160None  L68VV88I, A91T, L101I, K111KR, S119R, T124N, T125S, K156N, K211R, D286NB
 hnxx100hnxx100KC988156None  L68VV88I, A91T, L101I, S119R, T124N, T125S, K156N, K211R, D278N, C280SB
 hnr121hnr121KC988071None  L68VK71Q, A91T, L101I, S119R, T124N, T125S, K156N, T218I, L234I, D278NB
 hnsy51hnsy51KC988136None  L68VV88I, A91T, L101I, S119R, T124N, T125S, K156N, K188R, K211R, D278EB
 hnsy24hnsy24KC988135None  L68VE11D, S17C, A91T, L101I, S119R, T124N, T125S, K156N, V165I, K211RB
 hnwsx69hnwsx69KC988073None  L68VV88I, A91T, L101I, K111R, S119R, T125S, K156N, V176L, K211RB
 hnxx197hnxx197KC988159None  L68VV88I, A91T, L101I, S119R, T124N, T125S, K211RB
 hnsy69hnsy69KC988139None  L68VV88I, A91T, L101I, S119R, T122I, T124N, T125S, K156N, V176L, K211RB
 hnsx29hnsx29KC987978None  L68VV88I, A91T, L101I, S119R, T125S, K156N, K211RB
 hnhy37hnhy37KC987985None  L68VV88I, A91T, L101I, S119R, T125S, K156N, K211RB
 hnsy16hnsy16KC987989None  L68VI60M, V88I, A91T, L101I, S119R, T124N, T125S, K156N, K211R, D278NB
 hnwsx34hnwsx34KC988140None  L68VV88I, A91T, L101I, S119R, T124N, T125S, K156N, K211RB
 hnxx123hnxx123KC988157None  L68VS17C, V88I, A91T, L101I, S119R, T124N, T125S, K156N, K211R, A265V, D286NB
 hnhy67hnhy67KC988121None  L68VL28I, S39C, L45I, V88I, A91T, L101I, K111R, S119R, T124N, T125S, K156N, K211RB
 hnsy28hnsy28KC988162None  L68VM50I, A91T, L101I, S119R, T125S, K156N, K211RB
 hnwsx37hnwsx37KC988141None  L68VR20K, V88I, L101I, S119R, T124N, T125S, K156N, K188R, K211RB
 hnxx96hnxx96KC988155None  L68VA91T, L101I, S119R, T125S, K156N, K211RB
 hnxx75hnxx75KC988154None  L68VS17C, K71Q, V88I, A91T, L101I, S119R, T124N, T125A, K156N, V165I, D286NB
 hnqx88hnqx88KC987969None  L68VE11D, Y15YF, H16HCRY, S17C, A91T, L101I, S119R, T124N, T125S, Q137H, G163E, K211RB
 hnsy20hnsy20KC987976None  L68VI73V, V88I, A91T, L101I, S119R, T124N, T125S, K156N, K211RB
 hnsx41hnsx41KC988133None  L68VK14R, L28I, V88I, A91T, L101I, S119R, T124N, T125S, K156N, K211RB
 hnsx34hnsx34KC987981None  L68VV88I, A91S, L101I, T112I, S119R, T124N, T125S, K156N, K211R, S230NB
 hnxx257hnxx257KC987979None  L68VG70E, A91T, L101I, S119R, T124N, T125A, K156N, V201I, D278NB
 hnsy48hnsy48KC988167None  L68VV88I, A91T, L101I, S119R, T124N, T125S, K156N, R187K, K188R, K211R, S283GB
 hnsx33hnsx33KC987980None  L68VE11D, S17C, V88I, L101I, S119G, T122I, T124N, T125S, K156N, K211RB
 hnr68hnr68KC988070None  L68VS17N, L28I, L45I, K71Q, V88I, L101I, S119R, T125S, A133T, K156N, K211RB
 hnr14hnr14KC988068None  L68VM50I, V88I, A91T, L101I, S119R, T124N, T125S, K156N, K188R, K211RB
 hnsy49hnsy49KC987988None  L68VV88I, A91T, L101I, S119R, T124N, T125S, S153A, K156N, K211RB
 hnsx37hnsx37KC988131None  L68VE11D, G70E, V88I, L101I, T112I, S119R, T124N, T125S, K156N, K211RB
 hnr141hnr141KC988164None  L68VV88I, A91T, L101I, W108*, S119R, T124N, T125S, G163E, V201I, I208M, K211R, E212AB
 hnsx26hnsx26KC988130None  L68VV88I, A91T, L101I, K111R, S119R, T124N, T125P, S153A, K156N, G163E, R187K, K211RB
 hnsy57hnsy57KC988137None  L68VE10D, S17C, A91T, L101I, S119R, T125S, K156N, V165I, K211R, D256E, D278GB
 hnsx30hnsx30KC987986None  L68VL28I, L45V, V88I, A91T, L101I, S119R, T124N, T125S, K156N, K211R, S283GB
 hnsy58hnsy58KC988138None  L68VS17N, V88I, E96D, L101I, I113V, T124N, T125A, K156N, K211RB
Reigadas (2013)105105JX425573None  L68VK14R, S17N, V31I, S39C, L74I, L101I, S119T, T125A, G163E, H171Q, V201I, Q216HB
 126126JX425594None  L68VI72V, I73V, S119P, T122I, T124A, V201I, A205S, D256EB
 182182JX425649None  L68VS24N, L101I, S119P, T122I, N254K, D256EB
 248248JX425715None  L68VI72V, I73VB