<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation S230N
Rx >=1 INI
IncludeMixtures No
References 8
Patients 15
Isolates 27
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Baldanti (2009)PV1PV1GU350727RAL26  R20K, I72V, T112I, S119T, V201I, S230N, D232EB
Canducci (2009)pt7pt7w4EU908766RAL4  S24A, L101I, T112TI, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
  pt7w8EU908767RAL8  S24A, L101I, T125A, I135V, F181L, T206S, D229E, S230N, D256DEB
  pt7w12EU908768RAL13  S24A, L101I, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
  pt7w20EU908769RAL21  S24A, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
  pt7w24EU908770RAL26  S24A, L101LI, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
Garrido (2009)Pt10Pt10 RAL   E10D, V32I, S39C, L101I, T218S, S230N, D253EB
Sichtig (2009)Pt044833FJ183697RAL41N155HV151VI, G163GRS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
  4951FJ183698RAL50N155HV151I, G163RS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
Blanco (2011)CA794CA124207 RAL1  K14KR, R20K, I72V, L101I, I113L, G193E, I203IM, S230N, D278AB
  CA124206 RAL3  K14R, R20K, I72V, L101I, I113L, E170EK, G193E, S230N, D278AB
  CA124208 RAL17  R20K, I72V, L101I, I113L, G193E, S230N, D278AB
Garrido (2012)BAA295858BAA295858JQ716881RAL52  E10D, V32I, S39C, L101I, T218S, S230N, D253EB
 BAA295859BAA295859JQ716882RAL52  E10D, V32I, S39C, L101I, T218S, S230N, D253EB
 BAA295860BAA295860JQ716883RAL52  E10D, V32I, S39C, L101I, T218S, S230N, D253EB
 BAA295864BAA295864JQ716885RAL52  K7R, K14R, L101I, T112I, S230NB
Parczewski (2012)307307_18KC409156RAL196N155H E10D, L101I, T112I, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278GB
  307_xKC409158RAL201N155H E10D, L101I, T112I, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278GB
 549549_24KC409174RAL94  P90PS, L101I, T112I, E157Q, K160Q, K215KN, S230N, L234I, A265VB
  549_25KC409175RAL122  L101I, T112I, E157Q, K160Q, K215KN, S230N, L234I, A265V, S283SGB
 6060_40KC409182RAL246  L101I, T112I, E157Q, K160Q, K173R, I200L, V201I, S230N, L234I, L242LF, A265VB
  60_42KC409183RAL290  L101I, T112I, S119SN, E157Q, K160Q, K173R, I200L, V201I, S230N, L234I, A265V, G277GDB
  60_45KC409184RAL362  L101I, T112I, E157Q, K160Q, K173R, I200L, V201I, S230N, L234I, A265VB
 828828_7KC409201RAL82  E10D, M50I, L101I, T112I, E157Q, K160Q, S230N, L234I, D253E, D256EB
  828_8KC409202RAL107  E10D, M50I, L101I, T112I, E157Q, K160Q, S230N, L234I, D253E, D256EB
de Souza Cavalcanti (2014)BRSP94BRSP94 RAL N155HT97A, V151ID6E, E10D, A21S, A23V, S39R, M50I, L101I, S119P, T122I, K156R, A169V, S230N, L234I, S283NB
 BRSP73BRSP73 RAL N155H D25E, V31I, M154I, S230NB