<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation G163R
Rx >=1 INI
IncludeMixtures No
References 5
Patients 10
Isolates 11
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Malet (2008)2bH5-W18FJ538982RAL17N155HG163RV32I, S39C, M50I, T112I, I113V, T124N, V201I, L234V, S255RB
 HSH2H-SH2-W22FJ538994RAL22G140S, Q148HG163RS17N, R20K, L28I, S39C, G70R, T124A, T125A, V201I, I208LB
Sichtig (2009)Pt044951FJ183698RAL50N155HV151I, G163RS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
Brenner (2011)102001.076102001.076HQ423441RAL T66IT97A, G163RE11D, D25E, V31I, I60V, I72V, A91T, G106A, T112I, I113V, S119P, T124N, T125V, I203M, A205T, D256E, D278DYB
Canducci (2011)Pt7Pt7W40JN163898RAL39G140A, Q148RG163RE10G, K14R, V79I, T125V, K156N, I208M, D232N, D256EB
  Pt7W64JN163899RAL65G140S, Q148HG163RK14R, V79I, T112A, T125V, K156N, I208M, D256EB
de Souza Cavalcanti (2014)BRSP332BRSP332 RAL N155HT97A, V151I, G163RS17N, V31I, I72V, S119R, T124A, T125V, K156N, V165I, Q168R, V201I, R224Q, D256E, R269K, V281M, S283GB
 BRSP08BRSP08 RAL  L74M, T97A, V151I, G163RK14R, V31I, I72A, L101I, I113L, S119G, T122I, T124TN, K156KN, E157Q, V201I, T206S, S283GB
 BRSP614BRSP614 RAL G140S, Q148HG163RS17N, S39N, E96D, L101I, T124A, V201I, D278NB
 BRSP239BRSP239 RAL E138K, S147G, Q148RV151I, G163RK14R, L74I, V75M, V79I, S119P, T122I, T124A, T125A, K156N, V201I, T218I, L234V, D256E, S283G, R284GB
 BRSP65BRSP65 RAL G140S, Y143H, Q148HG163RE11D, K14R, V31I, L101I, I135V, V201I, K211T, L234IB