<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation G163R
Rx >=1 INI
IncludeMixtures No
References 6
Patients 32
Isolates 33
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Malet (2008)2bH5-W18FJ538982RAL17N155HG163RV32I, S39C, M50I, T112I, I113V, T124N, V201I, L234V, S255RB
 HSH2H-SH2-W22FJ538994RAL22G140S, Q148HG163RS17N, R20K, L28I, S39C, G70R, T124A, T125A, V201I, I208LB
Sichtig (2009)Pt044951FJ183698RAL50N155HV151I, G163RS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
Brenner (2011)102001.076102001.076HQ423441RAL T66IT97A, G163RE11D, D25E, V31I, I60V, I72V, A91T, G106A, T112I, I113V, S119P, T124N, T125V, I203M, A205T, D256E, D278DYB
Canducci (2011)Pt7Pt7W40JN163898RAL39G140A, Q148RG163RE10G, K14R, V79I, T125V, K156N, I208M, D232N, D256EB
  Pt7W64JN163899RAL65G140S, Q148HG163RK14R, V79I, T112A, T125V, K156N, I208M, D256EB
de Souza Cavalcanti (2014)BRSP332BRSP332 RAL N155HT97A, V151I, G163RS17N, V31I, I72V, S119R, T124A, T125V, K156N, V165I, Q168R, V201I, R224Q, D256E, R269K, V281M, S283GB
 BRSP08BRSP08 RAL  L74M, T97A, V151I, G163RK14R, V31I, I72A, L101I, I113L, S119G, T122I, T124TN, K156KN, E157Q, V201I, T206S, S283GB
 BRSP614BRSP614 RAL G140S, Q148HG163RS17N, S39N, E96D, L101I, T124A, V201I, D278NB
 BRSP239BRSP239 RAL E138K, S147G, Q148RV151I, G163RK14R, L74I, V75M, V79I, S119P, T122I, T124A, T125A, K156N, V201I, T218I, L234V, D256E, S283G, R284GB
 BRSP65BRSP65 RAL G140S, Y143H, Q148HG163RE11D, K14R, V31I, L101I, I135V, V201I, K211T, L234IB
Hurt (2014)IN_2564IN_2564 RAL Y143CV151VI, G163RE11D, S24N, D25E, V31I, V75M, L101I, L104M, T125A, A205T, T218S, S230K, N254K, S255G, R284GB
 IN_819IN_819 RAL Y143RG163RV31I, I72V, V75M, T206S, S230NB
 IN_668IN_668 RAL Y143CT97A, G163R, S230RS17N, T124A, T125A, K211Q, S283SGB
 IN_1078IN_1078 RAL N155HV151I, G163RK111R, T112I, T124A, V201IB
 IN_2222IN_2222 RAL E138K, S147G, Q148RG163RM50I, V79I, Y99F, L101I, M154MI, K156N, K211KRB
 IN_216IN_216 RAL N155HV151I, G163RS17N, V31I, S39N, I84M, L101I, I113V, T124A, T125A, E157Q, K160T, I208IM, K211T, S230N, A265AV, R269RK, D270HB
 IN_1753IN_1753 RAL N155HV151I, G163RL101I, K111RB
 IN_660IN_660 RAL N155HV151I, G163RD6E, E10D, M50I, I72V, S119P, T122I, T124N, V225VAB
 IN_1789IN_1789 RAL Y143RT97A, G163RS24N, S119P, T125A, I135V, T206S, T210I, S283GB
 IN_1177IN_1177 RAL N155HV151I, G163RI60L, I113V, I182V, V201I, I220IVB
 IN_816IN_816 RAL N155HV151I, G163RI60L, I72IV, I113V, I182V, V201I, S283SGB
 IN_1656IN_1656 RAL Y143RT97A, G163RE11D, S24N, D25E, V31I, L101I, K111R, T112A, S119P, T122I, T125A, R187K, I220L, K240KRB
 IN_1139IN_1139 RAL G140S, Q148RG163RK14R, V31I, L45I, I72V, K160N, D167E, T206S, T218S, D256EB
 IN_756IN_756 RAL N155HV151VI, G163RE11D, L101I, R187K, K188R, I220L, V281MB
 IN_2739IN_2739 RAL G140S, Q148RG163RL63V, I72V, L74I, T112TI, T124A, K156N, I182V, V201I, N254Q, V259IB
 IN_2908IN_2908 RAL Y143CG163R, S230RE11D, L28I, S39C, I72IV, L101I, I135V, F181L, V201I, K215NB
 IN_2519IN_2519 RAL Y143HL74M, T97A, G163RE11D, K14R, A21T, S24G, D25E, S39C, L45V, L101I, S119G, T122I, T125A, E170EG, T206TS, Q216H, S283SNB
 IN_2303IN_2303 RAL N155HE138ED, G163RM50I, L101LI, M154L, V201I, K211RB
 IN_1820IN_1820 RAL Y143CL74M, T97A, G163R, S230RL63LV, S119T, T124A, I203IM, K211KRB
 IN_1405IN_1405 RAL N155HT97A, V151I, G163RE11D, S17T, V31I, V79I, L101I, S119P, I135V, F181L, V201I, T206SB
 IN_293IN_293 RAL N155HV151I, G163RL45V, M50T, T124A, T125A, K156N, V165I, I182V, V201I, E212A, S283GB
 IN_315IN_315 RAL T66AL74M, V151VI, G163RV31I, V75VI, L101V, T112V, T125A, V126L, V165I, V201I, K211R, K215N, D229DN, S230N, D256E, S283GB