<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation G163Q
Rx II-naive
IncludeMixtures No
References 22
Patients 34
Isolates 35
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Sanabani (2006)02BR01102BR011DQ358809None  V151ID3E, L28I, P30A, I72V, L101I, V150A, E157Q, K160T, G163Q, V201IB
Brennan (2007)181615181615EF150602None   S17N, L28I, L45I, L101I, S119P, T122I, T124N, K160T, G163Q, V201I, Q216N, Q221K, D256EB
 437895437895EF150609None  V151ID3E, V31I, I72V, G163Q, K211Q, A265V, R269K, D278GB
 440163440163EF150611None   V31I, L101I, T124A, G163Q, T206S, I208L, T218I, Q221H, N222K, S255G, S283DB
Lataillade (2007)482-014ML_482-014EF472777None   S17N, T124A, K156N, G163Q, V201I, T218SB
Brumme (2009)INT_3989INT_3989FJ813440None   K14R, A21AT, V32I, S39SC, L101I, G163Q, V201I, T218TI, K219KQ, S230SN, D232DG, C280CRB
 H4570H4570GQ371919None   D6E, E11D, S17N, V31I, I72V, I113V, S119P, T122I, T125A, K156N, G163Q, T206S, R262RKB
Canducci (2009)pt5pt5blEU908771None   K14R, M22L, V32I, V37I, S39C, I72V, L101I, G163Q, V201I, D253EB
Eshleman (2009)437895437895FJ480246None  V151ID3E, V31I, I72V, G163Q, K211Q, A265AV, R269RK, D278GB
Garrido (2009)378INT-378GU217225None   S17N, I72V, T112I, T124N, G163Q, A248SB
Low (2009)ahi41ahi41_06FJ786308None   V31I, S39C, T124A, E157Q, G163Q, V201I, D232EB
Passaes (2009)BR.RJ.FT59BR.RJ.FT59HM026782None   K7R, K14R, V31I, I72V, L101I, K111Q, T112V, T124A, T125A, G163Q, D167E, V201I, A205S, T206S, D207E, T218SB
Wang (2009)CR0175SCR0175SFJ469703None   I72V, G163Q, A248SB
 F710F710FJ469729None   E10D, M50I, I72V, S119P, T124N, T125A, V126L, G163Q, T206S, I208L, L234I, D253E, D256EB
Canducci (2011)Pt5Pt5BLJN163890None   Q9H, K14R, A23G, V32I, V37I, I72V, L101I, I161F, G163Q, V201I, D253E, V281G, A282GB
Kousiappa (2011)CY216CY216JF683765None   I72V, G163Q, K215N, A248SB
 CY246CY246JF683791None   E10D, E11Q, I72V, G163Q, K215N, A248S, S255NB
 CY267CY267JF683808None   I72V, G163Q, K215N, A248SB
Sanabani (2011)BR1046BR1046JN692447None   D6E, S17N, I72V, T112I, T124N, T125V, G163Q, A205SB
Molina (2012)30243024_1 None   E10D, V31I, M50T, L101I, K136Q, G163Q, K211R, S283GB
 41734173_1 None  T97AK14R, R20K, V31I, V32VA, A33AT, L101I, T112IV, T124A, T125A, G134N, I135V, G163Q, G193E, V201I, T206S, T218TI, Y227F, L234I, S255N, D256E, D279G, S283GB
Capel (2013)111111KC238637None   K111KIRT, G163Q, V201I, T206S, K211R, I220F, Q221HB
 6464KC238600None   R20RS, I72V, P90S, L101I, G163QB
Reigadas (2013)6565JX425533None   E11D, S24N, V31I, L45V, K103R, S119P, T122I, T125A, G163Q, V201IB
 129129JX425597None  T97AV31I, T93S, L101I, T124A, K156N, G163Q, V201I, D279G, D286NB
 211211JX425678None   K14R, V31I, G106A, G163Q, V201I, T218I, S230N, D256EB
Chikata (2014)KI-548KI-548AB873985None   E11D, A21T, A23V, D25E, T125TA, G163Q, V201IB
Stekler (2014)PIC1878PGK58PIC1878PGK58KJ151976None   E11D, S24N, D25E, V31I, M50I, V77I, I84M, K111Q, T112A, T125A, G163Q, L234I, D253E, D278NB
Kinloch (2015)INT_75INT_75KT167634None   I89V, G163QB
Pessoa (2016)10BR_RJ07810BR_RJ078KT427769None  V151IE10D, M50I, I72V, G163Q, S230NB
 10BR_RJ10710BR_RJ107KT427750None  V151ID3E, K7R, V31I, I72V, P90S, G163Q, K188R, V201I, A265VB
Hachiya (2017)C14-51111622LC160879LC160879None   E11D, L28I, V37I, L101I, S119G, T122I, T124A, T125A, G163Q, V201I, K215N, Q221S, N222KB
 H15-2060173LC161352LC161352None   E11D, A23V, L28I, V31VI, V37I, L101I, S119G, T122I, T125A, G163Q, V201I, K215N, Q221S, N222K, L234X, D256E, R269K, D278S, R284GB
Meixenberger (2017)99-0005999-00059KM677519None  V151AE11D, V31I, G163Q, V201I, I208M, S230NB
 02-0006102-00061KM677552None   S17SN, K34KR, L101I, T112V, S119G, T122I, G163Q, V201I, D256DGB