<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation G163Q
Rx >=1 INI
IncludeMixtures No
References 5
Patients 10
Isolates 14
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Canducci (2009)pt5pt5w4EU908772RAL4  K14R, M22L, V32I, V37I, S39C, I72IV, L101I, G163Q, V201I, D253EB
  pt5W12EU908774RAL13 Y143SK14R, M22L, V32I, V37I, S39C, L101I, G163Q, V201I, D253EB
  pt5w24EU908775RAL26N155NHV151IK14R, M22L, V32I, V37I, S39C, L101I, T125A, G163Q, E170Q, V201I, D253EB
  pt5w48EU908777RAL52 T97A, Y143S, S230RK14R, M22L, V32I, V37I, S39C, L101I, G163Q, V201I, D253EB
Canducci (2011)Pt5Pt5W12JN163891RAL13 Y143S, S230RQ9H, K14R, A23G, V32I, V37I, L101I, G163Q, V201I, D253EB
  Pt5W48JN163892RAL52 T97A, Y143S, S230RQ9H, K14R, A23G, V32I, V37I, L101I, G163Q, V201I, D253EB
Garrido (2012)BAA295889BAA295889JQ716890RAL52G140S, Q148H D6E, K14R, S17SN, V31I, L101I, K111KE, A128AV, I135V, G163Q, G193E, V201I, D256EB
Molina (2012)30243024_2 RAL34N155H E10D, V31I, M50T, L101I, S119R, K136Q, G163Q, K211R, I217IV, S283GB
 41734173_2 EVG43 T97AK14R, R20K, V31I, L101I, T112IV, T124A, T125A, G134N, I135V, G163Q, G193E, V201I, T206S, T218TI, Y227YF, L234I, S255N, D256E, D279G, S283GB
Hurt (2014)IN_646IN_646 RAL G140S, Q148H R20K, V31I, Y99F, L101I, T122I, T124A, T125AV, G163Q, V201I, I208IM, L234IB
 IN_1416IN_1416 RAL E138AT, G140GS, Q148H S17N, I72IV, K111KN, T112TI, T124A, T125A, V126VF, I141IV, K156KN, G163Q, K211RB
 IN_1770IN_1770 RAL Y143R D25E, V31I, M50MI, L74I, K111KR, S119T, T125A, G163Q, V201VI, T218SB
 IN_266IN_266 RAL Y143RL68V, L74M, T97AV31I, L101I, S119T, G163Q, F181L, T206SB
 IN_1276IN_1276 RAL E92EQ S17N, K111R, T112M, T124A, T125A, G163Q, K264KR, D270DEB