<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation M154L
Rx >=1 INI
IncludeMixtures No
References 4
Patients 6
Isolates 14
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Baldanti (2009)PV8PV8GU350728RAL26  K7Q, L101I, T125V, I135V, M154L, V165I, K211R, D256EB
 PV5PV5GU350729RAL26G140S, Q148H E13D, L101I, M154L, V165I, A196P, V201I, I208L, L234V, D256EB
Canducci (2009)pt4pt4W4EU908760RAL4 R263KD3Q, G70E, L101I, S119R, T124N, T125A, M154L, V165I, K211R, Q252X, D256E, R262EB
  pt4W12EU908761RAL13  D3Q, G70E, L101I, S119R, T124N, T125A, M154L, V165I, K211R, D256EB
  pt4W24EU908762RAL26Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  pt4w32EU908763RAL35Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211KR, D256EB
  pt4w36EU908764RAL39Y143CL74M, T97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211R, D256EB
Blanco (2011)CA5016CA128616 RAL29  S119G, T122I, T125A, M154L, I203M, L234I, D256EB
 CA14192CA128613 RAL35  T112V, M154L, V201IB
Canducci (2011)Pt2Pt2W24JN163881RAL26Y143CT97AL101I, S119R, T124N, T125A, M154L, V165I, D256E, G277CB
  Pt2W36JN163882RAL35 L74M, T97A, Y143GL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277CB
  Pt2W37JN163883RAL36 L74M, T97A, Y143GI36V, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  Pt2W56JN163884RAL55Y143RT97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277RB
  Pt2W64JN163885RAL64E138A, Y143CL74M, T97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G272E, G277RB