<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation M154I
Rx >=1 INI
IncludeMixtures No
References 8
Patients 13
Isolates 14
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Baldanti (2009)PV10PV10GU350735RAL52  E10D, S24N, L101I, M154I, G163S, V165I, K240TB
 PV3PV3GU350736RAL13G140S, Q148H, N155H S17N, I72V, T124A, M154I, E170A, V201IB
Sichtig (2009)Pt085255FJ183703RAL76N155HV151VI, G163GRT112I, T124N, M154I, V201I, D232DNB
Hatano (2010)4Virus15GU121691RAL Y143RT97AK7R, S17N, V31I, L101I, T112A, T125A, M154I, V201IB
  Virus16GU121692RAL Y143RT97A, G163GRK7R, S17N, V31I, L101I, T112A, S119T, T125A, M154I, V201VIB
Blanco (2011)ACM_09BLACM_09BL RAL N155H E10D, S119G, T122I, T124N, T125A, M154I, K211RB
 GCC_10BLGCC_10BL RAL N155HV151IA21S, M22I, A23V, S24G, I84V, M154I, V165I, V201I, D232NB
Canducci (2011)Pt8Pt8w12JN163901RAL13Y143R, N155H S17N, A49S, I72V, T124A, M154I, E170A, V201I, G277RB
Fransen (2012)pt2pt2 RAL Y143YR, N155NHQ95QK, V151I, G163GRE10D, V31I, L101I, M154I, V165I, V201IB
Garrido (2012)BAA295911BAA295911JQ716900RAL52  G4GE, L101LI, M154I, I220VB
de Souza Cavalcanti (2014)BRSP73BRSP73 RAL N155H D25E, V31I, M154I, S230NB
 BRSP54BRSP54 RAL   S17N, I72V, I84M, N117T, T124A, T125A, M154I, V201I, Q221NB
 BRSP39BRSP39 RAL G140S, Q148H A23V, T125A, M154I, A169T, R187K, K188R, V201IB
 BRSP126BRSP126 RAL   S17N, I72V, T124A, M154I, V165I, V201I, Y227F, L234V, D256E, S283GB