<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation V151I
Rx >=1 INI
IncludeMixtures No
References 16
Patients 110
Isolates 123
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Malet (2008)H6H6-W20FJ538984RAL20N155HT97A, V151IE11D, V31I, L101I, K111T, I113V, S119T, T124N, T125A, S195C, A196P, A205T, T218S, D232NB
Canducci (2009)pt5pt5w24EU908775RAL26N155NHV151IK14R, M22L, V32I, V37I, S39C, L101I, T125A, G163Q, E170Q, V201I, D253EB
  pt5W36EU908776RAL39N155NHT97TA, Y143YS, V151IK14R, M22L, V32I, V37I, S39C, L101I, T125A, G163Q, E170EQ, V201I, A239T, D253K, D256E, I257K, V260RB
Garrido (2009)Pt04Pt04 RAL N155HV151IE11D, S17T, I72V, E198D, V201I, K211R, D270DAB
 Pt05Pt05 RAL N155HL74M, V151IE11D, R20K, L101I, S119P, T122I, T124A, S195T, I203M, Y227F, D253DY, S255N, D256EB
Sichtig (2009)Pt095358FJ183704RAL106N155HV151IK14KR, I72IV, T124A, I162V, E170AT, S195SR, I200L, V201I, I220L, L234I, I251ILB
 Pt044951FJ183698RAL50N155HV151I, G163RS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
Hatano (2010)3Virus9GU121685RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
  Virus10GU121686RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
  Virus11GU121687RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
  Virus12GU121688RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
 7Virus120GU121796RAL  V151ID25E, I72V, H78HR, K211R, K215N, L234LFB
  Virus129GU121805RAL G140S, Q148HV151ID25E, I72V, K211R, K215NB
Blanco (2011)GCC_10BLGCC_10BL RAL N155HV151IA21S, M22I, A23V, S24G, I84V, M154I, V165I, V201I, D232NB
Brenner (2011)INT12INT12_1HQ207812RAL N155HL74LM, V151I, G163GRE11D, S24N, V31I, L101I, S119P, T122I, K136Q, V150A, K211R, D286NB
 081911.030081911.030HQ423437RAL N155HV151I, G163GRE11D, S24N, L101I, S119P, T206S, D207E, E212AB
Armenia (2012)PT_141PT_141_MO_6JN544113RAL N155HV151I, G163GRD6T, K7E, E11D, K14R, V31I, M50I, I72IV, I113V, S119SR, T125A, V201I, D256E, V281VMB
Fransen (2012)pt2pt2 RAL Y143YR, N155NHQ95QK, V151I, G163GRE10D, V31I, L101I, M154I, V165I, V201IB
 pt3pt3 RAL G140GS, Q148QHR, N155NHV151IE11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
 pt4pt4 RAL E92EQ, G140GS, Y143YR, Q148QR, N155NHV151IS17N, V31I, V79VI, L101I, T124A, L234IB
 pt5pt5 RAL G140GS, Y143YR, Q148QH, N155NHV151I, G163GRE10D, K14R, A23V, L28I, P30A, S39C, L101I, T124A, F185Y, V201I, T206S, Q216HB
Lee (2012)350841205A.8JQ666926RAL30N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
Molina (2012)32533253_3 EVG48N155NHV151IE11D, R20KE, S39SG, D41N, G70GR, T112I, V201IB
 30543054_3 RAL70N155HV151IL101I, K156N, I208LB
  3054_4 RAL81N155HV151IL101I, K156N, I208LB
 32223222_2 EVG13 V151IE10D, V31I, M50MI, I84IML, L101I, G106A, K111KREG, T112X, T124TA, T125TA, I135IV, V180VIB
  3222_3 EVG39S147GV151IE10D, V31I, M50I, I72IV, L101I, G106A, T112S, T124A, T125TA, I135IV, D232DNB
  3222_4 EVG51S147GQ95QK, V151IE10D, V31I, M50I, L101I, G106A, T112S, T124A, I135IV, S230SN, D232DNB
 33763376_2 RAL17 V151IM50I, V201VIB
Souza Cavalcanti (2012)BRSPBR10SP267CJQ797720RAL74F121YT97A, V151IE11D, K14R, S24D, L28I, S39C, I72V, L74I, S119P, Q137H, Q164K, R187K, V201I, D232E, L234FB
de Souza Cavalcanti (2014)BRSP332BRSP332 RAL N155HT97A, V151I, G163RS17N, V31I, I72V, S119R, T124A, T125V, K156N, V165I, Q168R, V201I, R224Q, D256E, R269K, V281M, S283GB
 BRSP94BRSP94 RAL N155HT97A, V151ID6E, E10D, A21S, A23V, S39R, M50I, L101I, S119P, T122I, K156R, A169V, S230N, L234I, S283NB
 BRSP08BRSP08 RAL  L74M, T97A, V151I, G163RK14R, V31I, I72A, L101I, I113L, S119G, T122I, T124TN, K156KN, E157Q, V201I, T206S, S283GB
 BRSP37BRSP37 RAL N155HT97A, V151IS17N, A21S, D25E, L28I, S39C, L101I, S119R, T218SB
 BRSP160BRSP160 RAL  V151IV31I, I72V, P90S, L101I, K136QB
 BRSP10BRSP10 RAL  T97A, V151IS17N, S24A, G59E, I60L, I72V, L101I, T112V, T124N, T125AB
 BRSP24BRSP24 RAL N155HE138D, V151IE10D, A21S, E170AB
 BRSP553BRSP553 RAL E92QL74M, V151IE10D, A21S, M50I, K211RB
 BRSP380BRSP380 RAL N155HE138D, V151IE11D, D25E, L28I, V37I, S39C, M50L, L74I, L101LF, T124A, E157Q, K160T, I203M, I208M, D232N, L234I, D253E, N254GB
 BRSP267BRSP267 RAL F121YT97A, V151IE11D, K14R, S24D, L28I, S39C, I72V, L74I, S119P, Q137H, Q164K, R187K, V201I, D232E, L234FB
 BRSP101BRSP101 RAL N155HV151IS17N, L101I, S119ST, T124TA, K136Q, E157Q, K160T, A169V, L172LI, I208M, D232N, L234I, D253E, D256EB
 BRSP363BRSP363 RAL N155HV151I, G163QRS17N, L28I, P30T, I84L, L101I, K111R, T112A, S119T, T124A, T125A, K136Q, Q177R, V201I, K211R, T218M, L234V, D256E, M275V, S283G, D286NB
 BRSP385BRSP385 RAL N155HV151IS24G, S119P, T122I, T124A, T125A, V201I, A205S, S255NB
 BRSP268BRSP268 RAL N155HV151IS17N, L28I, T112I, S119G, T122I, T124N, T125A, E157Q, K160Q, V201IB
 BRSP2823BRSP2823 RAL  V151IL101I, G193E, V201I, D256E, D279GB
 BRSP359BRSP359 RAL N155HV151ID6T, K7E, E10D, V31I, K71KQ, I72V, I84M, A91R, L101I, T112I, V201I, T206S, D279DNB
 BRSP496BRSP496 RAL E92Q, N155HV151IH12Q, K14R, A21S, A23T, V31I, L101I, T124A, I204V, K215N, D279NB
 BRSP95BRSP95 RAL N155HT97A, V151ID6N, K7E, M50I, L101I, S119P, V201I, T206S, I208L, K211R, E212L, D232NB
 BRSP379BRSP379 RAL  V151IK7Q, E11D, R20K, V31I, L101I, I135V, V201I, D256EB
 BRSP591BRSP591 RAL  V151IS17N, L101I, S119P, T124N, T125A, I135V, S195C, D256EB
 BRSP141BRSP141 RAL  V151IE10D, I72V, I84L, L101I, A128AV, I203IM, T218I, L234IB
 BRSP239BRSP239 RAL E138K, S147G, Q148RV151I, G163RK14R, L74I, V75M, V79I, S119P, T122I, T124A, T125A, K156N, V201I, T218I, L234V, D256E, S283G, R284GB
 BRSP705BRSP705 RAL E92Q, N155HV151IE10D, A21SB
 BRSP128BRSP128 RAL N155HV151ID3E, S17N, A21S, S24N, I72V, V77A, L101I, I113V, T124A, D232NB
 BRSP273BRSP273 RAL Y143YC, N155HV151IS17N, A21S, V31I, L101I, K103R, T124A, I135V, V201I, T218L, K219Q, L234V, D256E, S283GB
 BRSP231BRSP231 RAL N155HA128T, V151IS17N, L28I, I72V, I208L, L234H, S283GB
Hardy (2014)Pt1INTPt1INT1202 RAL, DTG69N155HV151IR20K, V31I, L45I, L101I, S119SR, I135V, E157Q, K160Q, V201I, K215NB
  Pt1INT1212 RAL, DTG110E138K, S147G, N155HT97A, V151ID6DN, R20RK, V31I, L45I, L101I, S119R, I135V, E157Q, K160Q, V201I, K215NB
  Pt1INT1310 RAL, DTG157E138K, S147G, N155HT97A, V151IR20K, V31I, L45I, A49P, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB
  Pt1INT1401 RAL, DTG168E138K, S147G, N155HT97A, V151IR20RK, V31I, L45I, A49P, L68LF, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB
Hurt (2014)IN_1019IN_1019 RAL T66TI, N155HL74M, T97A, V151ID6E, S17N, M50I, I72V, L101LI, S119R, K156N, V201VI, I208M, E212AB
 IN_883IN_883 RAL E92QT97A, V151IS17N, L28I, A49P, I72IV, K111R, S119T, T124A, T125A, V165VIB
 IN_210IN_210 RAL N155H, R263RKV151IE11D, K14R, S17T, A23V, L28I, P30A, I72V, V201I, T206S, D232DNB
 IN_729IN_729 RAL N155HV151IE11D, K14R, V31I, D41DN, M50MI, I84LV, T97V, L101LV, I113V, S119R, K156KN, E157Q, K160KQ, V201I, T206S, I208M, T218S, R284RGB
 IN_1808IN_1808 RAL N155HV151I, G163KD6E, E11D, S24N, V31I, K42R, M50I, I73V, L74I, I84L, Q95H, L101I, I113L, T124HQ, E157Q, K160Q, V201I, T206S, K211R, L234LV, K240RB
 IN_750IN_750 RAL N155HV151ID25DE, V31I, M50I, D232N, A265VB
 IN_1894IN_1894 RAL N155HV151IS17N, D55DE, I72V, A98G, K111R, I113V, T124A, T125A, V126F, E170A, V201I, I220L, I251VB
 IN_376IN_376 RAL N155HE138D, V151IS17N, M50L, L101I, T124A, D167E, K188R, I220L, D232N, I251IL, A265V, R269RKB
 IN_1078IN_1078 RAL N155HV151I, G163RK111R, T112I, T124A, V201IB
 IN_1171IN_1171 RAL N155HV151I, G163GRV31VI, L101I, T112I, I135IV, F181FL, I220L, D232DN, D253DEB
 IN_2544IN_2544 RAL Y143YH, N155HT97TA, V151IS17N, M50I, G59GE, L101I, T112TR, S119R, T124A, I135IV, K156N, E157Q, V201I, T218TSB
 IN_1565IN_1565 RAL N155HV151IE11D, S24N, M50MI, L101I, S119P, T122I, I135V, Y194YH, D256EB
 IN_920IN_920 RAL N155HV151IL45I, M50R, E69D, I72V, L74I, I84L, L101I, T112R, T125A, E157Q, K160Q, G163V, V201I, E212A, K215N, D256E, R284GB
 IN_385IN_385 RAL N155HV151IE11D, S24N, V31VI, M50I, L68F, L74I, T112R, I113V, S119P, T122I, T124N, E157Q, K160Q, V201I, I203IM, T206S, I208L, K211KR, E212AB
 IN_713IN_713 RAL N155HV151I, G163KS17N, A21S, D25E, N27ND, L45I, L101I, G106A, K111R, T112R, T124A, E157Q, K160Q, I208L, D256E, D278A, S283GB
 IN_353IN_353 RAL N155HV151IS39C, M50I, T125A, V126M, E157Q, K160Q, G193E, I203M, I208IM, D232N, D286NB
 IN_216IN_216 RAL N155HV151I, G163RS17N, V31I, S39N, I84M, L101I, I113V, T124A, T125A, E157Q, K160T, I208IM, K211T, S230N, A265AV, R269RK, D270HB
 IN_2237IN_2237 RAL N155HV151IS17N, V31I, L101I, T124A, T125A, G163V, V201I, I220L, D232N, D256EB
 IN_2128IN_2128 RAL N155HV151IM50I, L101I, K111T, S119R, Y227F, S230SN, D253H, D256EB
 IN_2453IN_2453 RAL N155HV151IK7R, S17N, L28I, P30A, M50I, I72V, L101I, T112A, T124A, T125A, K136R, K156N, V201I, T218S, L234H, D256E, M275VB
 IN_1753IN_1753 RAL N155HV151I, G163RL101I, K111RB
 IN_801IN_801 RAL N155HE138D, V151I, G163KS17N, V31I, M50I, L101I, T124N, V201IB
 IN_2616IN_2616 RAL N155HV151I, G163KV31I, L101I, T112TA, E157EQ, K160KT, K188R, I203M, L234IB
 IN_3310IN_3310 RAL N155HE138D, V151IS17N, V31I, T124N, T125A, V126L, I135IV, K136KT, K156N, V201I, T206S, D232N, D256EB
 IN_1210IN_1210 RAL N155HV151IS17N, L101I, K111R, T112V, S119R, S123C, T124N, K156N, E157Q, Q177L, D256EB
 IN_660IN_660 RAL N155HV151I, G163RD6E, E10D, M50I, I72V, S119P, T122I, T124N, V225VAB
 IN_1092IN_1092 RAL N155HV151IK7KR, S17N, V31I, M50I, I72IV, Q95P, L101I, T112A, S119R, K156N, E157Q, S283GB
 IN_1177IN_1177 RAL N155HV151I, G163RI60L, I113V, I182V, V201I, I220IVB
 IN_2391IN_2391 RAL N155HV151IE11D, A21AT, L101I, K111Q, S119P, T122I, D279DNB
 IN_2914IN_2914 RAL N155HV151I, G163GRD6E, S17N, I72IV, A80S, L101I, T112TA, T124N, T125V, G193E, E212A, N254NKB
 IN_816IN_816 RAL N155HV151I, G163RI60L, I72IV, I113V, I182V, V201I, S283SGB
 IN_463IN_463 RAL F121FY, N155NHV151I, G163GRV31I, L101I, T125TA, E198D, V201I, D232DNB
 IN_2774IN_2774 RAL N155HL74M, V151I, G163KS17N, L68T, L101I, T124A, V201I, T218S, I220L, Y227F, D253N, D256E, R284GB
 IN_2785IN_2785 RAL E92QT97A, V151IE11D, K14R, S24N, D41DN, L63I, L74I, L101I, T112S, T125A, G163E, V201I, I208M, L234V, D279GB
 IN_2885IN_2885 RAL N155HV151I, G163EKE10ED, L101V, T124N, T125A, I135V, H171HR, V201I, L234I, D256EB
 IN_369IN_369 RAL N155HV151IE10D, I72V, I84V, I135V, M154I, V201I, D232NB
 IN_1418IN_1418 RAL G140S, Q148HV151IE10D, V31VIM, M50T, I72V, I113V, T124A, T125A, Q216NB
 IN_770IN_770 RAL N155HV151IE11D, K14R, V31I, D41N, M50MI, I84IL, T97V, L101LV, I113V, S119R, E157Q, K160KQ, V201I, T206S, I208M, T218S, R284RGB
 IN_2058IN_2058 RAL N155HT97A, V151IR20K, M50IT, I72V, L101I, S119R, T124A, G193E, K211R, L234LV, D278A, D286NB
 IN_549IN_549 RAL N155HV151IE11D, V31VI, I72V, L101I, I113V, T124S, T125M, I161L, D232DN, N254H, D256EB
 IN_574IN_574 RAL N155HL74M, V151IK7R, E11D, V31I, M50I, I113V, S119P, T122I, T124TN, I208L, K211Q, E212A, Q216N, I220IMB
 IN_2847IN_2847 RAL N155HV151IM50I, L101I, K111AT, S119R, E157EQ, K160KQ, I203IM, K211KR, Y227F, D253HY, D256EB
 IN_2789IN_2789 RAL N155HV151IV31I, M50MV, I72IV, L101I, T112I, I113V, K156N, E157Q, V201I, T218S, D229N, D253E, D256E, R284GB
 IN_2378IN_2378 RAL N155HE138D, V151IK14R, R20K, V32I, L45I, L101V, K136Q, G163A, V201I, T206S, I220V, D232DNB
 IN_3034IN_3034 RAL N155HV151IS17N, V31I, I72V, L74I, L101I, I113V, T124S, T125A, I135IV, K156N, H171Q, F181L, V201I, T206S, Q221R, D232DN, A265V, R284IB
 IN_2559IN_2559 RAL N155HL74LIM, A128T, E138D, V151IM50L, E157Q, K160Q, G163AB
 IN_1531IN_1531 RAL N155HV151IS17N, R20RK, V31I, M50MI, L101I, A196P, V201I, D232N, D256EB
 IN_1500IN_1500 RAL N155HL74LM, E138ED, V151ID3N, S17N, S39C, M50I, I72V, K156N, E157Q, K173R, D232NB
 IN_2350IN_2350 RAL N155HA128AT, V151IS17N, L28I, I72V, P90S, S119T, E157Q, K160Q, D232E, R284GB
 IN_87IN_87 RAL N155HV151I, G163GRD6E, E10D, V31I, S39N, G70GR, I72V, L101I, G106A, S119PT, A205S, I208M, K211KT, K240KR, D253E, S255N, D256EB
 IN_1993IN_1993 RAL N155HV151IK14KR, V31VI, M50I, L74I, L101I, T124S, I135V, E157Q, K160T, F181L, Y194YC, V201I, T206S, K211KR, T218S, I220L, Y227F, D253Y, I268L, S283GB
 IN_1549IN_1549 RAL N155HE138D, V151IK14R, R20RK, N27NH, P30PA, V32I, L45LI, L101IV, K136Q, G163A, V201I, T206S, I220V, D232DN, I257IVB
 IN_2470IN_2470 RAL Y143CT97A, V151ID6DE, K14KR, A21AT, M50I, L101I, S119R, L234VB
 IN_1202IN_1202 RAL N155HV151IE11D, A21T, A23V, I72IV, L101I, K111Q, T122I, T124A, V201I, D279NB
 IN_397IN_397 RAL N155HV151IE11D, D25DE, V31I, S39C, L45Q, L101I, E157EQ, K160KN, D167DE, V201I, D232NB
 IN_863IN_863 RAL N155HV151IE11D, S17T, A23V, M50I, L101I, T124A, T125TA, I135V, R187RK, S283SG, Q285PB
 IN_1322IN_1322 RAL N155HV151IE11D, V31I, I135V, F181L, S195T, V201I, D232NB
 IN_1033IN_1033 RAL Y143YH, N155HV151IS17N, L28I, L45LV, M50I, T124N, D167E, K211R, Y227F, D232DN, S255N, D256EB
 IN_2269IN_2269 RAL N155HV151IK14KR, R20K, L101I, T124A, I135IV, E157Q, K160Q, G193E, V201I, D232N, D286NB
 IN_2336IN_2336 RAL N155HV151II72IV, G106A, T124A, G193R, V201I, T206S, D232N, D253E, A265V, I268VB
 IN_1405IN_1405 RAL N155HT97A, V151I, G163RE11D, S17T, V31I, V79I, L101I, S119P, I135V, F181L, V201I, T206SB
 IN_293IN_293 RAL N155HV151I, G163RL45V, M50T, T124A, T125A, K156N, V165I, I182V, V201I, E212A, S283GB
Hachiya (2015)N816N816LC022720RAL N155HV151IE11D, L28I, V31I, V32I, V37I, C56Y, S119P, T122I, T124N, G163A, V201I, K211R, L234V, A248SB