<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation V151I
Rx >=1 INI
IncludeMixtures No
References 13
Patients 42
Isolates 51
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Malet (2008)H6H6-W20FJ538984RAL20N155HT97A, V151IE11D, V31I, L101I, K111T, I113V, S119T, T124N, T125A, S195C, A196P, A205T, T218S, D232NB
Canducci (2009)pt5pt5w24EU908775RAL26N155NHV151IK14R, M22L, V32I, V37I, S39C, L101I, T125A, G163Q, E170Q, V201I, D253EB
Garrido (2009)Pt04Pt04 RAL N155HV151IE11D, S17T, I72V, E198D, V201I, K211R, D270DAB
 Pt05Pt05 RAL N155HL74M, V151IE11D, R20K, L101I, S119P, T122I, T124A, S195T, I203M, Y227F, D253DY, S255N, D256EB
Sichtig (2009)Pt095358FJ183704RAL106N155HV151IK14KR, I72IV, T124A, I162V, E170AT, S195SR, I200L, V201I, I220L, L234I, I251ILB
 Pt044951FJ183698RAL50N155HV151I, G163RS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
Hatano (2010)3Virus9GU121685RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
  Virus10GU121686RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
  Virus11GU121687RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
  Virus12GU121688RAL N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
 7Virus120GU121796RAL  V151ID25E, I72V, H78HR, K211R, K215N, L234LFB
  Virus129GU121805RAL G140S, Q148HV151ID25E, I72V, K211R, K215NB
Blanco (2011)GCC_10BLGCC_10BL RAL N155HV151IA21S, M22I, A23V, S24G, I84V, M154I, V165I, V201I, D232NB
Brenner (2011)INT12INT12_1HQ207812RAL N155HL74LM, V151I, G163GRE11D, S24N, V31I, L101I, S119P, T122I, K136Q, V150A, K211R, D286NB
 081911.030081911.030HQ423437RAL N155HV151I, G163GRE11D, S24N, L101I, S119P, T206S, D207E, E212AB
Armenia (2012)PT_141PT_141_MO_6JN544113RAL N155HV151I, G163GRD6T, K7E, E11D, K14R, V31I, M50I, I72IV, I113V, S119SR, T125A, V201I, D256E, V281VMB
Fransen (2012)pt2pt2 RAL Y143YR, N155NHQ95QK, V151I, G163GRE10D, V31I, L101I, M154I, V165I, V201IB
 pt3pt3 RAL G140GS, Q148QHR, N155NHV151IE11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
 pt4pt4 RAL E92EQ, G140GS, Y143YR, Q148QR, N155NHV151IS17N, V31I, V79VI, L101I, T124A, L234IB
 pt5pt5 RAL G140GS, Y143YR, Q148QH, N155NHV151I, G163GRE10D, K14R, A23V, L28I, P30A, S39C, L101I, T124A, F185Y, V201I, T206S, Q216HB
Lee (2012)350841205A.8JQ666926RAL30N155HV151ID6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275VB
Souza Cavalcanti (2012)BRSPBR10SP267CJQ797720RAL74F121YT97A, V151IE11D, K14R, S24D, L28I, S39C, I72V, L74I, S119P, Q137H, Q164K, R187K, V201I, D232E, L234FB
de Souza Cavalcanti (2014)BRSP332BRSP332 RAL N155HT97A, V151I, G163RS17N, V31I, I72V, S119R, T124A, T125V, K156N, V165I, Q168R, V201I, R224Q, D256E, R269K, V281M, S283GB
 BRSP94BRSP94 RAL N155HT97A, V151ID6E, E10D, A21S, A23V, S39R, M50I, L101I, S119P, T122I, K156R, A169V, S230N, L234I, S283NB
 BRSP08BRSP08 RAL  L74M, T97A, V151I, G163RK14R, V31I, I72A, L101I, I113L, S119G, T122I, T124TN, K156KN, E157Q, V201I, T206S, S283GB
 BRSP37BRSP37 RAL N155HT97A, V151IS17N, A21S, D25E, L28I, S39C, L101I, S119R, T218SB
 BRSP160BRSP160 RAL  V151IV31I, I72V, P90S, L101I, K136QB
 BRSP10BRSP10 RAL  T97A, V151IS17N, S24A, G59E, I60L, I72V, L101I, T112V, T124N, T125AB
 BRSP24BRSP24 RAL N155HE138D, V151IE10D, A21S, E170AB
 BRSP553BRSP553 RAL E92QL74M, V151IE10D, A21S, M50I, K211RB
 BRSP380BRSP380 RAL N155HE138D, V151IE11D, D25E, L28I, V37I, S39C, M50L, L74I, L101LF, T124A, E157Q, K160T, I203M, I208M, D232N, L234I, D253E, N254GB
 BRSP267BRSP267 RAL F121YT97A, V151IE11D, K14R, S24D, L28I, S39C, I72V, L74I, S119P, Q137H, Q164K, R187K, V201I, D232E, L234FB
 BRSP101BRSP101 RAL N155HV151IS17N, L101I, S119ST, T124TA, K136Q, E157Q, K160T, A169V, L172LI, I208M, D232N, L234I, D253E, D256EB
 BRSP385BRSP385 RAL N155HV151IS24G, S119P, T122I, T124A, T125A, V201I, A205S, S255NB
 BRSP268BRSP268 RAL N155HV151IS17N, L28I, T112I, S119G, T122I, T124N, T125A, E157Q, K160Q, V201IB
 BRSP2823BRSP2823 RAL  V151IL101I, G193E, V201I, D256E, D279GB
 BRSP359BRSP359 RAL N155HV151ID6T, K7E, E10D, V31I, K71KQ, I72V, I84M, A91R, L101I, T112I, V201I, T206S, D279DNB
 BRSP496BRSP496 RAL E92Q, N155HV151IH12Q, K14R, A21S, A23T, V31I, L101I, T124A, I204V, K215N, D279NB
 BRSP95BRSP95 RAL N155HT97A, V151ID6N, K7E, M50I, L101I, S119P, V201I, T206S, I208L, K211R, E212L, D232NB
 BRSP379BRSP379 RAL  V151IK7Q, E11D, R20K, V31I, L101I, I135V, V201I, D256EB
 BRSP591BRSP591 RAL  V151IS17N, L101I, S119P, T124N, T125A, I135V, S195C, D256EB
 BRSP141BRSP141 RAL  V151IE10D, I72V, I84L, L101I, A128AV, I203IM, T218I, L234IB
 BRSP239BRSP239 RAL E138K, S147G, Q148RV151I, G163RK14R, L74I, V75M, V79I, S119P, T122I, T124A, T125A, K156N, V201I, T218I, L234V, D256E, S283G, R284GB
 BRSP705BRSP705 RAL E92Q, N155HV151IE10D, A21SB
 BRSP128BRSP128 RAL N155HV151ID3E, S17N, A21S, S24N, I72V, V77A, L101I, I113V, T124A, D232NB
 BRSP273BRSP273 RAL Y143YC, N155HV151IS17N, A21S, V31I, L101I, K103R, T124A, I135V, V201I, T218L, K219Q, L234V, D256E, S283GB
 BRSP231BRSP231 RAL N155HA128T, V151IS17N, L28I, I72V, I208L, L234H, S283GB
Hardy (2014)Pt1INTPt1INT RAL, DTG69N155HV151IR20K, V31I, L45I, L101I, S119SR, I135V, E157Q, K160Q, V201I, K215NB
  Pt1INT RAL, DTG110E138K, S147G, N155HT97A, V151ID6DN, R20RK, V31I, L45I, L101I, S119R, I135V, E157Q, K160Q, V201I, K215NB
  Pt1INT RAL, DTG157E138K, S147G, N155HT97A, V151IR20K, V31I, L45I, A49P, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB
  Pt1INT RAL, DTG168E138K, S147G, N155HT97A, V151IR20RK, V31I, L45I, A49P, L68LF, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB