<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation Q148K
Rx >=1 INI
IncludeMixtures No
References 3
Patients 5
Isolates 5
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Hatano (2010)10Virus109GU121785RAL G140GS, Q148KH51HYS24SG, L101I, T112I, K211Q, I217VB
Brenner (2011)092810.002092810.002HQ423435RAL E138K, G140A, Q148K S17N, L28I, P30A, I60V, G106A, T115M, T124TN, I208M, D232N, D256EB
Hurt (2014)IN_1916IN_1916 RAL G140A, Q148K S17N, N27H, V31I, E35Q, S39N, D41N, M50I, L101I, G163T, G193E, V201I, T218S, I220L, Y227F, L234VB
 IN_946IN_946 RAL E138K, G140A, Q148K T112I, T122I, T124N, D256E, D278DG, R284G, D288NB
 IN_2253IN_2253 RAL E138K, G140A, Q148K E11D, A21T, V31I, L45V, L101I, K111T, I113V, T125A, G163T, I203M, T218S, K219KT, D253E, D256E, D279GB