<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation S147G
Rx >=1 INI
IncludeMixtures No
References 5
Patients 10
Isolates 16
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Hatano (2010)17Virus99GU121775EVG E138K, S147G, Q148R K7KR, I72V, V79VI, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
  Virus100GU121776EVG E138K, S147G, Q148RV54VIK7KR, I72V, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
  Virus103GU121779EVG E138K, S147G, Q148RV54VIK7KR, E35EQ, I72IV, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
  Virus20GU121696EVG E138K, S147G, Q148RV54IK7KR, E35EK, I72V, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
Molina (2012)32223222_3 EVG39S147GV151IE10D, V31I, M50I, I72IV, L101I, G106A, T112S, T124A, T125TA, I135IV, D232DNB
  3222_4 EVG51S147GQ95QK, V151IE10D, V31I, M50I, L101I, G106A, T112S, T124A, I135IV, S230SN, D232DNB
de Souza Cavalcanti (2014)BRSP239BRSP239 RAL E138K, S147G, Q148RV151I, G163RK14R, L74I, V75M, V79I, S119P, T122I, T124A, T125A, K156N, V201I, T218I, L234V, D256E, S283G, R284GB
Hardy (2014)Pt1INTPt1INT RAL, DTG110E138K, S147G, N155HT97A, V151ID6DN, R20RK, V31I, L45I, L101I, S119R, I135V, E157Q, K160Q, V201I, K215NB
  Pt1INT RAL, DTG157E138K, S147G, N155HT97A, V151IR20K, V31I, L45I, A49P, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB
  Pt1INT RAL, DTG168E138K, S147G, N155HT97A, V151IR20RK, V31I, L45I, A49P, L68LF, L101I, S119R, T122TAIV, I135V, E157Q, K160Q, V201I, K215N, L234VB
Hurt (2014)IN_1622IN_1622 RAL E138K, S147G, Q148RQ95KK14R, R20K, V32I, L45V, L101I, K103R, T124A, G163E, V201I, K215N, N222K, D270HB
 IN_65IN_65 RAL E138K, S147G, Q148R K7R, K14R, K71N, V79VI, A91AT, S119R, T124N, T125A, K156N, G193E, V201I, N222K, S230N, L234VB
 IN_2222IN_2222 RAL E138K, S147G, Q148RG163RM50I, V79I, Y99F, L101I, M154MI, K156N, K211KRB
 IN_2095IN_2095 RAL E138K, S147G, Q148RV54VI, V151VIV31I, A49P, L74I, V79I, L101I, T124TA, I141V, I203IM, I204IVB
 IN_1638IN_1638 RAL E138K, S147G, Q148RQ95KK14R, R20K, V32I, L45V, L101I, K103R, T124A, G163E, V201I, K215N, N222K, D270HB
 IN_727IN_727 RAL S147G, Q148RH114YE11D, V31VIM, I113V, T124N, T125V, L158V, S195TB