<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation Y143H
Rx >=1 INI
IncludeMixtures No
References 4
Patients 7
Isolates 7
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Canducci (2009)pt6pt6w48EU908754RAL52E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, R224RGB
Canducci (2011)Pt1Pt1W48JN163879RAL43E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, G277RB
de Souza Cavalcanti (2014)BRSP328BRSP328 RAL G140S, Y143H, Q148H S17N, S24A, L28I, L101I, T112S, S119P, K156S, V201VI, D232NB
 BRSP65BRSP65 RAL G140S, Y143H, Q148HG163RE11D, K14R, V31I, L101I, I135V, V201I, K211T, L234IB
Hurt (2014)IN_880IN_880 RAL G140S, Y143H, Q148H S17N, K34R, T124R, T125A, V201I, S230NB
 IN_2519IN_2519 RAL Y143HL74M, T97A, G163RE11D, K14R, A21T, S24G, D25E, S39C, L45V, L101I, S119G, T122I, T125A, E170EG, T206TS, Q216H, S283SNB
 IN_928IN_928 RAL E92Q, Y143HL68VV31I, T112TA, S119T, V201I, T206S, M275MV, S283GB