<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation Y143G
Rx >=1 INI
IncludeMixtures No
References 2
Patients 4
Isolates 5
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Canducci (2011)Pt2Pt2W36JN163882RAL35 L74M, T97A, Y143GL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277CB
  Pt2W37JN163883RAL36 L74M, T97A, Y143GI36V, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
Hurt (2014)IN_1564IN_1564 RAL  L74M, T97A, Y143G, G163GRS17N, S39N, L101I, T112A, S119R, T124A, T125A, I135V, Y194L, S195H, A196T, K211KR, S230SN, I268L, D270H, R284RGB
 IN_2231IN_2231 RAL  T97A, Y143GE11D, V31I, V32I, V37I, L63I, I72IV, L74I, L101I, T112TK, T115S, S119R, T124TN, V201I, S230NB
 IN_160IN_160 RAL  L74LM, T97TA, Y143GS17SN, S39N, L101I, I113IL, T124N, T125TA, G163T, T218S, K219N, N222K, D229N, S230N, D253E, D256EB