<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation Y143C
Rx >=1 INI
IncludeMixtures No
References 9
Patients 26
Isolates 30
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Canducci (2009)pt4pt4W24EU908762RAL26Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  pt4w32EU908763RAL35Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211KR, D256EB
  pt4w36EU908764RAL39Y143CL74M, T97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211R, D256EB
Wittkop (2009)66_M3GU358398RAL12Y143CL74LM, Q95QK, V151VI, S230RK7KR, S17N, V31I, T97TP, K111T, I113V, T124Q, T125A, A169AV, G189GV, I203MB
Blanco (2011)CA1556CA124202 RAL85Y143CL74M, T97A, S230RK7R, S17N, L101I, K111Q, T112K, S119R, T206S, K211R, D256EB
Brenner (2011)INT6INT6_1HQ207828RAL Y143C, N155HS230RS17N, M50I, L101I, T112I, T124N, G163E, A169S, V201I, T206S, I220L, Q221S, D279GB
Canducci (2011)Pt2Pt2W24JN163881RAL26Y143CT97AL101I, S119R, T124N, T125A, M154L, V165I, D256E, G277CB
  Pt2W64JN163885RAL64E138A, Y143CL74M, T97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G272E, G277RB
Armenia (2012)PT_229PT_229_MO_9JN544121RAL Y143C, N155HS230RK7R, S17N, L101I, S119P, T122I, K156N, V165I, V201I, T206S, T218S, K219N, D256E, D278A, V281VMB
  PT_229_MO_11JN544122RAL Y143C, N155HS230RK7R, S17N, E69EQ, L101I, S119P, T122I, K156N, V165I, V201I, T206S, T218S, K219N, N222NK, D256DE, D278A, V281VMB
de Souza Cavalcanti (2014)BRSP710BRSP710 RAL Y143C, N155HS230RV31I, L101I, T112I, S119T, T124A, E157Q, K160Q, V201I, C280SB
Hurt (2014)IN_2589IN_2589 RAL Y143CT97A, S230RK14R, L63LI, L74I, L101I, S119ST, G134GE, D167E, I208L, K211QB
 IN_2414IN_2414 RAL Y143CV54I, T97A, S230RS17N, V31VI, L74I, L101I, T112A, S119T, T124A, R187K, K188R, K211R, D256EB
 IN_2564IN_2564 RAL Y143CV151VI, G163RE11D, S24N, D25E, V31I, V75M, L101I, L104M, T125A, A205T, T218S, S230K, N254K, S255G, R284GB
 IN_3146IN_3146 RAL Y143CT97A, S230RK14R, V31I, Q95AT, L101I, S119T, T124A, V201IB
 IN_668IN_668 RAL Y143CT97A, G163R, S230RS17N, T124A, T125A, K211Q, S283SGB
 IN_2478IN_2478 RAL Y143CS230RV31I, M50I, G163T, K173KR, T206S, T218S, I220MB
 IN_1391IN_1391 RAL Y143CT97A, S230RK14R, V31I, Q95A, L101I, S119T, T124A, M154L, V201IB
 IN_1752IN_1752 RAL E138K, Y143CL74M, T97A, A128T, S230RE13D, K14KR, S17N, V31I, L63LI, L101I, T112A, S119R, K156N, I208L, Q252K, D288NB
 IN_2493IN_2493 RAL Y143CL74M, T97A, S230RS17N, V31I, D41N, L63I, L101I, S119R, T124A, G163T, T218S, K219N, N222K, D229DG, S283GB
 IN_1795IN_1795 RAL Y143CT97A, G163GR, S230RS17N, R20RK, V31I, A80S, L101I, S119T, T124A, T125A, T206S, D256E, S283GB
 IN_224IN_224 RAL Y143CS230RD6DE, E11D, E13ED, L28I, V37I, M50I, V79VI, V201I, K215N, T218S, D278DAB
 IN_2723IN_2723 RAL Y143C, N155HS230RE10D, E11D, L28I, P30A, S39C, A49P, E69Q, L101I, S119T, V201I, K211T, T218S, M275V, S283GB
 IN_2250IN_2250 RAL Y143CT97A, S230RS17N, C56CR, I72V, F100Y, L101I, K111T, I113L, T124R, T125A, I203M, T206S, I208L, E212L, T218SB
 IN_2843IN_2843 RAL Y143C, N155HS230RE10D, E11D, L28I, P30A, S39C, A49P, E69Q, L101I, S119T, V201I, K211T, Q216QR, T218S, M275V, D278DN, S283GB
 IN_2908IN_2908 RAL Y143CG163R, S230RE11D, L28I, S39C, I72IV, L101I, I135V, F181L, V201I, K215NB
 IN_286IN_286 RAL Y143CS230RE11D, R20RK, D25E, Q95N, L101I, G106A, S119T, I135V, E157Q, K160Q, G193E, I203M, I208L, D256E, D286NB
 IN_2470IN_2470 RAL Y143CT97A, V151ID6DE, K14KR, A21AT, M50I, L101I, S119R, L234VB
 IN_1820IN_1820 RAL Y143CL74M, T97A, G163R, S230RL63LV, S119T, T124A, I203IM, K211KRB
Hachiya (2015)N241N241LC022658RAL Y143CT97AS39C, L74V, L101I, S119R, T124A, T125A, I135V, F181L, V201I, D232NB