<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation G140S
Rx >=1 INI
IncludeMixtures No
References 18
Patients 213
Isolates 241
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Charpentier (2008)Pt3Pt3-W15 RAL15G140S, Q148R I72V, T124TA, K156N, D167E, S283G, D288NB
Malet (2008)1aSH1-W12FJ538986RAL13G140S, Q148H K7Q, E11D, V31I, M50L, I72V, L101I, T124A, I135V, I200L, V201I, I220LB
 1bH-SH1-W16FJ538991RAL15G140S, Q148H E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
 1cSH2-W10FJ538988RAL11G140S, Q148H S17N, L28I, S39C, S119P, T122I, T124A, T125AB
 HSH2H-SH2-W22FJ538994RAL22G140S, Q148HG163RS17N, R20K, L28I, S39C, G70R, T124A, T125A, V201I, I208LB
Baldanti (2009)PV5PV5GU350729RAL26G140S, Q148H E13D, L101I, M154L, V165I, A196P, V201I, I208L, L234V, D256EB
 PV3PV3GU350736RAL13G140S, Q148H, N155H S17N, I72V, T124A, M154I, E170A, V201IB
Canducci (2009)pt6pt6W12EU908750RAL13G140S, Q148R D3N, L101I, K156N, I208LB
  pt6W36EU908753RAL39G140S, Q148HT97AL101I, S119R, K156N, I208LB
  pt6w48EU908754RAL52E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, R224RGB
 pt3pt3w24EU908758RAL26G140S, Q148HV54IV31I, I113V, T124A, T125A, V201I, K215NB
Garrido (2009)Pt02Pt02 RAL G140S, Q148R E11D, V31VI, V32I, V37I, L101I, V201I, D232E, D256EB
Sichtig (2009) 5068FJ183700RAL35G140S, Q148HG163KS17N, R20K, L28I, S39C, L45V, I113V, T124N, T125A, V201I, V259IB
  5864FJ183701RAL79G140S, Q148HG163EKQS17N, R20K, L28I, S39C, L45V, I113L, T124N, T125A, V201IB
Wittkop (2009)11_M6GU358379RAL25G140S, Q148H E10D, R20K, V32I, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, Q221S, N222KB
  1_M9GU358380RAL39E138EA, G140S, Q148H E10D, R20K, V32I, L45LI, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, Q221S, N222K, V259VIB
  1_M12GU358381RAL52E138EA, G140S, Q148H E10D, R20K, V32VI, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, Q221S, N222K, V259VIB
 55_M1GU358392RAL4G140S, Q148H E11D, E13D, V31I, M50I, S57G, I89V, S119P, T122I, T124A, T206S, S255N, D256E, S283GB
  5_M3GU358393RAL12G140S, Q148H E11D, E13D, V31I, M50I, S57G, S119P, T122I, T124A, T206S, S255N, D256E, S283GB
  5_M6GU358394RAL25G140S, Q148H E11D, E13D, V31I, M50I, S57G, L63LI, S119P, T122I, T124A, T206S, T210TS, S255N, D256E, S283GB
  5_M9GU358395RAL39G140S, Q148HL74LME11D, E13D, V31I, K34KR, M50I, S57G, L63I, S119P, T122I, T124A, T206S, I208IL, S255N, D256E, S283GB
 22_M6GU358401RAL25G140S, Q148H D3DN, E10ED, R20K, K160R, V201IB
  2_M9GU358402RAL39G140S, Q148H D3DN, R20K, K160R, V201IB
Hatano (2010)1Virus4GU121680RAL G140S, Q148H S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212A, R284G, D286NB
  Virus5GU121681RAL G140S, Q148H S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212A, R284G, D286NB
 2Virus114GU121790RAL G140S, Q148H L63I, I73V, L74I, E96D, L101I, T112I, I208L, D232E, L234LFB
  Virus8GU121684RAL G140S, Q148H L63I, I73V, L74I, E96D, L101I, T112I, I208L, D232EB
 5Virus27GU121703RAL G140S, Q148H S17N, I72V, L101I, K156N, V201I, D207DG, I208LB
 7Virus129GU121805RAL G140S, Q148HV151ID25E, I72V, K211R, K215NB
Blanco (2011)CA8070CA124205 RAL29G140S, Q148H K14R, L101I, T112A, G193E, D279GB
  CA124204 RAL85G140S, Y143YH, Q148H K14R, L63I, L101I, T112A, G193E, D279GB
  CA128615 RAL113G140S, Q148H K14R, Q44QH, L63I, L101I, T112A, G193E, D229E, D279GB
  CA153556 RAL161G140S, Q148H K14R, L63I, L101I, T112AS, G193E, V201VI, D229E, D279GB
 CLD_01_BCLD_01_B RAL G140S, Q148H E11D, S24G, L28I, L101I, I113L, T122I, T124A, V201VIB
 DCR_02BLDCR_02BL RAL G140S, Q148H A23V, V31I, T125V, D232E, A265VB
 JRM_04BLJRM_04BL RAL G140S, Q148H K14R, V32I, S39C, L101I, T112I, I135V, V201I, T206S, T218S, I220V, K240R, C280S, D286NB
Brenner (2011)INT21INT21HQ207822RAL G140S, Q148H L45V, L101I, E157Q, K160Q, K215N, D232N, D256EB
 092807.021092807.021HQ423434RAL G140S, Q148H E11D, M50I, G193E, V201I, D232DN, D256E, D286DNB
 093107.007093107.007HQ423436RAL G140S, Q148HG163EKV31I, L45I, L101I, S119G, T122I, E157Q, K160Q, V176L, V201I, I208M, K215N, L234I, D253H, D256EB
 090808.001090808.001HQ423438RAL G140S, Q148H E11D, V31VIM, L101I, K111AS, T125TA, I135V, K156N, R187K, V201I, I220IV, S283SGB
 1080610806HQ423445RAL G140S, Q148H E11D, S24N, D25E, M50I, K111T, T112TK, I203MB
Canducci (2011)Pt1Pt1w12JN163876RAL13G140S, Q148R L101I, K156N, I208LB
  Pt1W24JN163878RAL26G140S, Q148HT97AL101I, S119R, K156N, I161F, I208LB
  Pt1W48JN163879RAL43E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, G277RB
 Pt4Pt4W24JN163889RAL26G140S, Q148HV54IV31I, I113V, T124A, T125A, V201I, K215N, G277CB
 Pt7Pt716JN163897RAL13G140S, Q148R T125V, K156N, I208M, D256EB
  Pt7W64JN163899RAL65G140S, Q148HG163RK14R, V79I, T112A, T125V, K156N, I208M, D256EB
 Pt10Pt10w28JN163906RAL30G140S, Q148H S24N, L101I, T125A, V201I, Q216HB
  Pt10w32JN163907RAL35G140S, Q148H S24N, D41N, L74I, A91T, L101I, T125A, V201I, Q216H, N254SB
Armenia (2012)PT_27PT_27_MO_10JN544092RAL G140S, Q148H E11D, V32I, D41N, A91AV, L101I, K111T, N222HB
 PT_84PT_84_MO_4JN544109RAL G140S, Q148R D6S, K7E, S17N, I72V, V201I, D256EB
  PT_84_MO_5JN544110RAL G140S, Q148QR D6S, K7E, S17N, I72V, Q164QR, V201I, D256E, A276ATB
Garrido (2012)BAA295893BAA295893JQ716870RAL52G140S, Q148H E11D, S24N, V31I, T112IM, T206S, I208L, D253DEB
 BAA295889BAA295889JQ716890RAL52G140S, Q148H D6E, K14R, S17SN, V31I, L101I, K111KE, A128AV, I135V, G163Q, G193E, V201I, D256EB
Lee (2012)318041193A.8JQ666905RAL28G140S, Q148H S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212A, R284G, D286NB
Molina (2012)33263326_2 RAL42G140S, Q148H E11D, S24N, K34R, I72IV, I84M, A91T, L101I, T125V, I161T, V201I, K211KR, S230N, V260L, P261F, S283GB
  3326_3 RAL48G140S, Q148H E11D, S24N, K34R, I72IV, I84M, A91T, L101I, T125V, I161IT, V201I, K211R, S230N, S283GB
 41184118_3 RAL48G140S, Q148H S17SN, R20RK, N27G, L28I, L45Q, I72IV, P90PL, Q216QH, D256DE, D279DGB
 41474147_2 RAL98G140S, Q148H V31I, K111T, S119G, T122I, T125A, Q164QP, Q168QP, H171HP, R231K, D288NB
 31333133_2 RAL71G140S, Q148H S24G, D25E, L28I, E35Q, L45V, T125A, V201I, S230N, S283R, R284GB
  3133_3 RAL81G140S, Q148H S24G, D25E, L28I, E35Q, L45V, T125A, V201I, S230N, S283R, R284GB
 32633263_4 RAL66G140S, Q148HE138D, R263RKK14R, S17N, V31VI, I60M, L101I, T112V, T124A, I135V, K188KR, V201I, A265V, S283G, R284G, D286NB
 31353135_2 RAL25G140S, Q148H K111KT, N254K, A265AV, S283GB
Parczewski (2012)103103_42KC409138RAL84G140S, Q148H E11D, R20K, G70D, I73IV, L101I, S119R, T124N, G193E, S195T, T206S, T218TS, D270NB
  103_43KC409139RAL96G140S, Q148H E11D, R20K, G70D, L101I, S119R, T124N, G193E, S195T, T206S, T218TS, D270NB
  103_46KC409140RAL145G140S, Q148H E11D, R20K, G70D, L101I, S119R, T124N, T125TS, G193E, S195T, T206S, T218TS, D270NB
  103_49KC409141RAL180G140S, Q148H E11D, R20K, G70D, K71KR, L101I, S119R, T124N, T125TS, G193E, S195T, T206S, T218S, D270NB
de Souza Cavalcanti (2014)BRSP328BRSP328 RAL G140S, Y143H, Q148H S17N, S24A, L28I, L101I, T112S, S119P, K156S, V201VI, D232NB
 BRSP172BRSP172 RAL G140S, Q148H R20K, V31I, M50I, I72V, V77VA, I84V, L101I, S119P, T122I, G163A, V201IB
 BRSP526BRSP526 RAL G140S, Q148H K7Q, R20RK, L63V, S119P, T122I, T124A, T125A, V165VI, K219N, N222K, S283SGB
 BRSP2822BRSP2822 RAL G140S, Q148HV151VIE11D, V31I, L63I, L101I, T112I, I113IL, G193E, V201I, N254K, D279GB
 BRSP287BRSP287 RAL G140S, Q148HT97AK14KR, R20K, G70E, L101I, T112V, S119R, T124S, T125A, V201I, D232NB
 BRSP67BRSP67 RAL G140S, Q148H S17N, R20K, V31I, S39R, L45V, L63I, I72IV, L101I, T112M, T124A, F139Y, F181L, V201IB
 BRSP614BRSP614 RAL G140S, Q148HG163RS17N, S39N, E96D, L101I, T124A, V201I, D278NB
 BRSP306BRSP306 RAL G140S, Q148H E10D, L101I, S119P, K136N, D232NB
 BRSP74BRSP74 RAL E138A, G140S, Q148HT97AS17N, I72V, L101I, S119R, K156N, K188R, V201I, K211R, I268L, D270NB
 BRSP367BRSP367 RAL G140S, Q148H D6E, S17N, R20K, M22L, L28M, E35Q, S39N, L101I, T125A, K136N, I200L, V201IB
 BRSP2821BRSP2821 RAL G140S, Q148H S17N, V32I, I72IV, L74I, T124A, T125M, K136Q, V165I, V201I, L234V, D256E, V259I, S283GB
 BRSP457BRSP457 RAL G140S, Q148HE138TD6T, K7E, V31I, I60IM, I72V, G163T, I208IM, L234V, D253E, D256EB
 BRSP148BRSP148 RAL G140S, Q148H S17N, A21S, D25E, V31I, L63LI, L74I, L101I, K111R, I113L, S119P, T122I, T125A, G163E, H171Q, T218S, S283GB
 BRSP368BRSP368 RAL G140S, Q148H D6E, E10D, D25E, V31I, S39N, I72V, L101I, T122I, T124A, K219N, N222KB
 BRSP594BRSP594 RAL G140S, Q148H D6N, K7D, V32I, L45V, L101I, T125A, I135VB
 BRSP458BRSP458 RAL E138AT, G140S, Q148H D6NS, K7E, S17N, V31I, L101I, T124TN, T125A, K156N, K160KR, I203M, Q221K, N222K, D256E, R284GB
 BRSP39BRSP39 RAL G140S, Q148H A23V, T125A, M154I, A169T, R187K, K188R, V201IB
 BRSP65BRSP65 RAL G140S, Y143H, Q148HG163RE11D, K14R, V31I, L101I, I135V, V201I, K211T, L234IB
 BRSP497BRSP497 RAL G140S, Q148H R20K, T112I, V201I, E212AB
 BRSP521BRSP521 RAL G140S, Q148H V31I, L63I, G70E, L101I, S119R, T122I, T125A, K160R, V201I, A205S, L234IB
 BRSP92BRSP92 RAL G140S, Q148H E11D, R20K, L45Q, S119P, T122I, S195T, I208L, L234H, D256EB
 BRSP14BRSP14 RAL G140S, Q148H Y15I, H16N, I72V, V88I, L101I, T122I, T125A, I135V, F181L, V201I, L234V, K273Q, D278NB
 BRSP577BRSP577 RAL G140S, Q148H S17N, L28I, I72V, T124S, I208M, S283GB
Hurt (2014)IN_937IN_937 RAL G140S, Q148H K7Q, E11D, R20RK, V31I, I113V, T124N, T125A, G193E, T218I, S230N, D256E, D286NB
 IN_1739IN_1739 RAL E138K, G140S, Q148H I72V, L101I, Y194C, I220M, N222K, Y227F, A265V, R284GB
 IN_207IN_207 RAL G140S, Q148H L63I, G70N, L101I, T125A, F181L, V201I, I208L, T218S, S283GB
 IN_1685IN_1685 RAL G140S, Q148H S17N, V31I, I72V, L101I, T112V, T124A, F185Y, T206S, I268L, D270HB
 IN_321IN_321 RAL G140S, Q148HT97AE11D, V31I, I72IV, T112TI, S119P, T122I, T125A, V126VL, G163GV, V201I, N254Q, S255GB
 IN_399IN_399 RAL E138K, G140S, Q148H E10D, V31I, A49P, I72V, T112A, T124A, K156N, V165IB
 IN_601IN_601 RAL E138A, G140S, Q148H E11D, S24N, D41N, I72V, T112A, S119P, L234LFB
 IN_2223IN_2223 RAL E138EK, G140S, Q148H K14R, S17C, M50I, I72V, T125A, I135V, M154I, R187RK, T206S, K219N, N222K, D286NB
 IN_94IN_94 RAL G140S, Q148H S39C, M50I, I72IT, L101I, V201I, T206S, K211R, K219N, D286NB
 IN_1807IN_1807 RAL G140S, Q148HE138DK14KR, S17N, R20RK, M50L, I60IM, T112V, T124A, K156KN, T206S, K211R, T218S, V259VIB
 IN_1628IN_1628 RAL E138EA, G140S, Q148H D25E, P30S, S39C, I72IV, T124N, T125AV, V201I, T206S, I220L, I251L, M275VB
 IN_1429IN_1429 RAL G140S, Q148H L101I, T124A, T125V, T206S, I208L, K215N, I220IL, Y227YF, N254K, S255G, I268L, R269K, D270H, S283GB
 IN_1725IN_1725 RAL G140S, Q148R A23V, I72V, K211QB
 IN_847IN_847 RAL G140S, Q148H K7KR, S17N, S24D, L28I, L45V, I72V, I84IM, T112TS, T124AS, S283SGB
 IN_633IN_633 RAL G140S, Q148H M50I, I72V, S119P, T122I, T124A, T125V, G163AE, D256E, S283GB
 IN_870IN_870 RAL G140S, Q148H H51HR, L101I, G106A, I113V, T124S, T125A, D167E, L234IB
 IN_197IN_197 RAL G140S, Q148H K14R, L28I, S39C, V201I, R284GB
 IN_1901IN_1901 RAL E138A, G140S, Q148H D25E, P30S, S39C, T124N, T125AV, V201I, T206S, I220L, I251L, M275VB
 IN_663IN_663 RAL E138K, G140S, Q148H I72V, L101I, Y194C, I220M, N222K, Y227F, A265V, R284GB
 IN_534IN_534 RAL E138EA, G140S, Q148H K14R, R20K, V31I, L101I, T124A, G193D, V201I, K211Q, T218I, R228RG, R231K, L234LF, A265V, R269K, D278AB
 IN_1185IN_1185 RAL G140S, Q148H E11D, V31I, V37I, L63I, L101I, K111T, S119T, T124N, T125V, I135V, V201I, S283GB
 IN_1064IN_1064 RAL G140S, Q148H S17N, A21S, A23V, V31I, L45V, I72IV, L101I, T124A, T125A, V126A, V176L, T218SB
 IN_2852IN_2852 RAL G140S, Q148H D25E, P30A, L101I, T112A, T125A, V201I, S230N, R231K, S283GB
 IN_1156IN_1156 RAL G140S, Q148HV151VAE11D, K14KR, L101I, F139FY, S195T, I203M, R284GB
 IN_646IN_646 RAL G140S, Q148H R20K, V31I, Y99F, L101I, T122I, T124A, T125AV, G163Q, V201I, I208IM, L234IB
 IN_1525IN_1525 RAL G140S, Q148H E11D, S24N, D25E, V31I, I72V, L101IV, S119P, T122I, T124A, M154I, V165I, T218S, D253EB
 IN_1083IN_1083 RAL G140S, Q148H V31I, K111T, I113V, T125A, G189GR, G197GR, I203MB
 IN_3026IN_3026 RAL G140S, Q148H G59GE, I72V, L101I, T112I, V201I, T206S, K215NB
 IN_1772IN_1772 RAL G140S, Q148H S17N, V31I, L45V, L101I, G163E, H171Q, V201I, T218S, L234IB
 IN_1859IN_1859 RAL G140S, Q148H K111R, D256E, D278A, S283G, R284GB
 IN_634IN_634 RAL G140S, Q148H M50I, I72V, S119P, T122I, T124A, T125V, G163AE, D256E, S283GB
 IN_265IN_265 RAL E138K, G140S, Q148H K14R, V31I, S39C, M50I, L101I, T124A, M154I, V201I, K211Q, S230N, L234I, D253EB
 IN_617IN_617 RAL G140S, Q148RL74IME11D, L28I, V37I, I72V, L101I, T112K, S119P, T122I, T124A, T125A, D167E, K211Q, Q216QR, L234V, A265VB
 IN_421IN_421 RAL G140S, Q148HL74MA23V, L101I, S283SGB
 IN_3178IN_3178 RAL G140S, Q148H S24G, S39C, I72V, G106A, G193E, V201I, D286NB
 IN_1378IN_1378 RAL G140S, Q148H R20K, D25DE, S39C, L101I, S119P, V201I, I203MB
 IN_1402IN_1402 RAL G140S, Q148H K7R, R20K, V31I, I60V, I72IV, E96D, L101I, T112I, T124N, T125V, I135V, I182V, V201I, I203M, Q216H, D256EB
 IN_1769IN_1769 RAL G140S, Q148HE92EKR20K, V31I, M50T, I84M, L101I, T112A, T124N, R199RKB
 IN_880IN_880 RAL G140S, Y143H, Q148H S17N, K34R, T124R, T125A, V201I, S230NB
 IN_44IN_44 RAL G140S, Q148H R20K, V31I, M50L, L101I, K136Q, I208L, D256EB
 IN_805IN_805 RAL G140S, Q148H R20RK, V31VI, L101I, I135V, G163A, A205S, D256E, S283SGB
 IN_2513IN_2513 RAL E138K, G140S, Q148H S17N, T124N, T125A, K127KR, M154I, V165IB
 IN_2520IN_2520 RAL G140S, Q148H K14R, K188R, V201I, K219T, I220L, D256EB
 IN_309IN_309 RAL E138EK, G140S, Q148H E11D, V31I, M154L, V201I, T218SB
 IN_477IN_477 RAL G140S, Q148H K7R, M50I, L101I, E157Q, K160Q, D167E, G193D, S195T, V201I, A265V, R269K, D270HB
 IN_81IN_81 RAL G140S, Q148RL74MS17SN, I72V, F100S, L101I, K111T, S119P, T124A, T125A, E157Q, K160KINB
 IN_1438IN_1438 RAL G140S, Q148H S17N, M50I, I72V, I113V, T124A, T125A, V201I, I220L, Y227F, R284GB
 IN_1750IN_1750 RAL G140S, Q148HL74IMVI72V, L101I, T125A, H171L, F181L, V201I, Q221QR, D256EB
 IN_1213IN_1213 RAL G140S, Q148H E11D, K14R, R20K, M50T, I113V, T124N, T125A, G193E, T206S, Q274QR, D288NB
 IN_552IN_552 RAL G140S, Q148H E11D, L28I, L45V, L101I, T124N, G193E, D256E, S283G, D288NB
 IN_188IN_188 RAL G140S, Q148HE138DK7R, S39C, L101I, T124N, V201I, T210S, I220L, Y227F, S283GB
 IN_2296IN_2296 RAL G140SQ148NM50I, T112I, K211Q, I217V, S230N, R231KB
 IN_1850IN_1850 RAL G140S, Q148H D6E, E10D, S17N, V31I, L101I, T124A, K136Q, T206S, S255N, D256EB
 IN_1204IN_1204 RAL E138EAKT, G140S, Q148H E11D, V31I, T93TN, L101I, K136KE, M154L, S195C, T218S, K219N, I220IL, N222K, S283G, R284GB
 IN_711IN_711 RAL G140S, Q148H E11D, A23V, N27NS, L28I, V31VI, S39C, M50I, S57SG, V88I, L101I, S119T, V201I, K215N, L234I, D253EB
 IN_222IN_222 RAL G140S, Q148H S17N, L28I, S39C, T218S, I220L, D232E, D278DN, S283G, R284RG, E287EAB
 IN_1456IN_1456 RAL E138A, G140S, Q148H S17N, S39SN, L101I, T124A, V165I, V201I, K211R, K219N, N222K, S230N, A265AV, I267IV, I268IL, K273Q, D278NB
 IN_1990IN_1990 RAL G140S, Q148H E10D, E11D, V31I, M50T, L101I, K111T, T112A, S119P, T122I, T218S, L234I, Q285QRB
 IN_548IN_548 RAL G140S, Q148H V31I, L101I, I161T, G163E, I182V, V201I, T218S, S230N, D256EB
 IN_2913IN_2913 RAL G140S, Q148H R20K, M50I, V88I, L101I, T112I, K136Q, V176L, V180VIB
 IN_1612IN_1612 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_2308IN_2308 RAL G140S, Q148H L101I, G193E, T206S, D288NB
 IN_1611IN_1611 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_914IN_914 RAL E138A, G140S, Q148H S17N, L45IT, L101I, T124A, T125A, V126VA, E157Q, K160Q, G163E, V165IB
 IN_3116IN_3116 RAL E138K, G140S, Q148H S24SN, V31I, M50I, T112TI, K188R, V201I, T206S, I208IL, K215S, S230G, K264RB
 IN_3184IN_3184 RAL G140S, Q148H K7KR, S17N, S24N, L101I, T112I, T124N, T125A, T206S, S230N, D256E, A265AV, D286DNB
 IN_1465IN_1465 RAL G140S, Q148H V31VI, M50I, I72V, L101I, M154L, I162VB
 IN_1031IN_1031 RAL E138EK, G140S, Q148H K14KR, S17N, M50L, L101I, K111Q, I113V, T124A, T125A, I141IV, V150VAIT, M154MI, T218SB
 IN_1486IN_1486 RAL G140S, Q148H E10D, D25DE, V31I, I72V, L101I, T122I, T124A, V201I, I220L, Y227F, S283GB
 IN_2953IN_2953 RAL G140S, Q148H E11D, A21T, S24G, D25E, L45V, T125TA, R166RK, K211KR, Q216HB
 IN_569IN_569 RAL G140S, Q148H K14R, R20RK, S39C, L101I, T124A, V201I, D253EB
 IN_3256IN_3256 RAL E138K, G140S, Q148H R20RK, S39C, M50MT, I84IL, L101I, K136N, M154I, D167E, V201I, K215KN, K244KRB
 IN_623IN_623 RAL G140S, Q148H S17N, S119P, T122I, T124A, T125A, V201I, T206S, E212A, Q216H, T218S, K219N, D256EB
 IN_2946IN_2946 RAL G140S, Q148H E10D, G59E, S119P, T122V, T124A, T125A, T218SB
 IN_1668IN_1668 RAL G140S, Q148H S17N, K34R, M50I, I72V, T124A, T206S, D256E, D270NB
 IN_708IN_708 RAL G140S, Q148HL74LMS17N, I72V, I84L, T97TS, L101I, T112I, T124A, M154I, V165I, L234VB
 IN_807IN_807 RAL G140S, Q148H E11D, S24N, V31I, I72V, D167E, V201I, I208L, S283G, D286NB
 IN_1275IN_1275 RAL G140S, Q148H K14R, A21T, L101I, I113IL, K219N, N222K, D256E, A276APB
 IN_2339IN_2339 RAL G140S, Q148H L28I, V37I, S39C, T112A, S119P, T124N, T125A, I208IL, T210TI, K211KR, T218S, D232DNB
 IN_3332IN_3332 RAL G140S, Q148H D6E, K14R, A21S, A23V, S24G, D25E, S39C, L45V, L101I, V201IB
 IN_1494IN_1494 RAL G140S, Q148H V31VI, K34KR, V201I, T206S, A265VB
 IN_1302IN_1302 RAL G140S, Q148H T124A, T125A, K156N, R187K, V201I, S230N, A276APB
 IN_156IN_156 RAL E138EK, G140S, Q148H K14KR, S17N, T124N, T125AV, M154I, V165IB
 IN_3123IN_3123 RAL G140S, Q148H K14KR, V31I, S39G, L101I, T124N, I208L, K215N, T218I, N222K, A265VB
 IN_1200IN_1200 RAL G140S, Q148R S17N, V31I, G106A, T125A, V126L, K156N, G163T, K173R, V201I, D253DN, D256EB
 IN_196IN_196 RAL G140S, Q148H S17N, L101I, T124A, K173R, V176LB
 IN_3306IN_3306 RAL G140S, Q148R S17N, V31I, L63I, L74I, L101I, T112TA, I113IL, K156N, Q216H, L234LV, D256EB
 IN_1336IN_1336 RAL G140S, Q148H E11D, S24N, D25E, K34R, M50T, V201I, T218S, S230N, V259VI, S283GB
 IN_2469IN_2469 RAL G140S, Q148H E11D, E13D, L101I, T112A, S119P, T122I, I208L, D256EB
 IN_838IN_838 RAL G140S, Q148H A49AT, I72V, K111T, V165I, F181L, V201I, D232EB
 IN_1652IN_1652 RAL E138EA, G140S, Q148H D25E, P30S, S39C, I72IV, T124N, T125AV, V201I, T206S, I220L, I251L, M275VB
 IN_539IN_539 RAL G140S, Q148HL74LMS24G, L45V, L101I, T112TAIV, I113IMV, T125AB
 IN_101IN_101 RAL G140S, Q148H S17N, V31I, L45V, L101I, I113V, T124A, T125A, G163E, F181L, V201IB
 IN_2457IN_2457 RAL G140S, Q148RG163KE11D, S24N, L101I, K111KR, T112A, T125A, K156NB
 IN_1641IN_1641 RAL G140S, Q148H E10D, E11D, A21T, M50I, I72V, I113L, S119P, T122I, T125A, L234I, D253E, D256EB
 IN_684IN_684 RAL G140S, Q148H S17SN, L101I, S119P, T122TI, K211R, Y227F, S230N, S255SN, D256E, A265VB
 IN_760IN_760 RAL G140S, Q148H M50I, I72V, S119P, T122I, T124A, T125V, G163AE, D256E, S283GB
 IN_1264IN_1264 RAL G140S, Q148H I72V, T112IM, T124N, V126F, V201I, T218S, D278DNB
 IN_1180IN_1180 RAL G140S, Q148H E11D, L28I, V37I, L101I, T112I, T206S, D256EB
 IN_1139IN_1139 RAL G140S, Q148RG163RK14R, V31I, L45I, I72V, K160N, D167E, T206S, T218S, D256EB
 IN_134IN_134 RAL G140S, Q148H D6E, E10D, E13D, I72V, T124G, T125A, V126L, L234LVB
 IN_1013IN_1013 RAL G140S, Q148H S17N, I72V, L101I, T124N, T125A, D167E, K173R, A179S, G193D, S195C, I220L, Y227F, S255N, D256E, D278N, S283GB
 IN_425IN_425 RAL E138KT, G140S, Q148H K7KR, E11D, S24N, V31I, L74I, S119R, S123C, T124N, K156N, G163GE, T218IL, L234IV, N254NKB
 IN_133IN_133 RAL G140S, Q148H E11D, R20K, D25E, V31I, V32I, D41N, K111T, T125A, V126M, I135V, V201I, T218SB
 IN_1784IN_1784 RAL E138EAKT, G140S, Q148H D6DN, S17N, V31I, M50I, L63LI, L101I, T112IMV, T124TA, K136KE, F139FY, V201VI, N254QB
 IN_1928IN_1928 RAL G140S, Q148H V31I, G70GR, K111T, T112TI, S119G, T122I, T125A, V201I, K211R, L242I, D256EB
 IN_1121IN_1121 RAL E138K, G140S, Q148RG163GRE11ED, K14KR, S39SN, L45LI, T112A, T124A, T125A, K136E, K156N, G193R, T206S, I208L, K211KQ, E212A, T218S, D232DN, L234I, A265AVB
 IN_2511IN_2511 RAL G140S, Q148R V31I, M50I, L101I, T124N, D167E, T206S, Y227F, S230N, D256E, A265VB
 IN_860IN_860 RAL G140S, Q148H L63I, T124N, T218IB
 IN_861IN_861 RAL G140S, Q148H K7Q, S17N, V31I, I72V, S119P, T122I, T124A, T125A, V126L, V165I, V201I, Q216H, D256E, A265VB
 IN_1386IN_1386 RAL E138A, G140S, Q148H E11D, D25E, S39T, L45Q, I60IM, I84L, G94A, L101I, T124N, G163A, K188R, Y194C, V201I, N222K, S230N, I268L, R284RGB
 IN_3328IN_3328 RAL G140S, Q148H S17N, D25E, I84V, L101I, T124S, T125M, I135V, M154I, D286NB
 IN_1418IN_1418 RAL G140S, Q148HV151IE10D, V31VIM, M50T, I72V, I113V, T124A, T125A, Q216NB
 IN_1390IN_1390 RAL G140S, Q148H E11D, S24N, D25E, V31I, L101I, I135V, V201I, N222NH, R284GB
 IN_11IN_11 RAL G140S, Q148H V31I, I72V, L101I, K111T, S119P, T122I, V180I, V201I, V259VI, D286NB
 IN_446IN_446 RAL E138EA, G140S, Q148H L63I, L101I, K111T, T124TA, I135V, F181L, I203IM, T206S, I208L, T210TS, K211KR, E212EAKT, T218SB
 IN_637IN_637 RAL G140S, Q148H E11D, V31I, L101I, G106A, K111Q, T122I, V150A, V201IB
 IN_832IN_832 RAL G140S, Q148H K7Q, L101I, T124N, I135V, F181L, V201I, T206S, K219N, N222K, I268L, D270HB
 IN_2312IN_2312 RAL G140S, Q148H E11D, L45Q, A91T, L101I, S195C, I203MB
 IN_1915IN_1915 RAL E138A, G140S, Q148H T124A, M154I, G193E, V201I, I208L, D278N, S283GB
 IN_1632IN_1632 RAL G140S, Q148H E10D, E11D, A21T, M50I, I72V, I113L, S119P, T122I, T125A, L234I, D253E, D256EB
 IN_373IN_373 RAL G140S, Q148H I72V, L101I, S119P, T125A, V126A, G193D, V201I, I268L, D270HB
 IN_2739IN_2739 RAL G140S, Q148RG163RL63V, I72V, L74I, T112TI, T124A, K156N, I182V, V201I, N254Q, V259IB
 IN_1868IN_1868 RAL G140S, Q148HE138DS17N, V31I, I72V, I113V, T124A, T125A, T206SB
 IN_1144IN_1144 RAL G140S, Q148H S17N, L28I, I72V, T112TI, I113IV, T124A, T125A, V126M, I141V, R284GB
 IN_755IN_755 RAL G140S, Q148H S17N, M50I, I72IV, I84IV, L101I, K111T, T124A, T125A, K156N, D167E, G193R, V201I, T206S, Q216N, S230N, D232DNB
 IN_2481IN_2481 RAL G140S, Q148H D41N, T124A, G193E, V201I, I208L, E212A, Q216H, T218SB
 IN_237IN_237 RAL G140S, Q148H E13D, K14R, V31VI, T124N, T125TAIV, V126VL, M154I, V201I, K211R, I217IV, D232DN, D256EB
 IN_1097IN_1097 RAL E138EA, G140S, Q148H S17N, E87D, T112A, T124N, T125A, M154I, V201VIB
 IN_1113IN_1113 RAL G140S, Q148H V31I, I72V, L101I, T112V, T122A, T124A, I135V, V201I, T218I, V225C, I251L, A265V, R269K, R284RTB
 IN_992IN_992 RAL G140S, Q148H S17N, L101I, S119G, T122I, T124A, T125A, K211Q, D256E, D278DNB
 IN_536IN_536 RAL G140SQ148NM50I, T112I, K211Q, I217V, S230N, R231KB
 IN_1309IN_1309 RAL G140S, Q148H K7R, S17N, I72V, L101I, T124TA, T125V, I220L, R224Q, L234I, V259VI, D270N, S283GB
 IN_782IN_782 RAL G140S, Q148H E11D, E13D, R20K, D25E, V31I, M50MI, T112A, T124A, T125A, V201I, A205S, I208M, K215N, R231K, N254K, S255G, K258RB
 IN_68IN_68 RAL G140S, Q148H M50I, T125VB
 IN_1634IN_1634 RAL G140S, Q148H E10D, E11D, A21T, M50I, I72V, I113L, S119P, T122I, T125A, L234I, D253E, D256EB
 IN_396IN_396 RAL G140S, Q148H I72V, Y99F, T124N, M154I, R187K, V201I, K211R, S230NB
 IN_422IN_422 RAL G140S, Q148HL74MA23V, L101I, S283SGB
 IN_1163IN_1163 RAL G140S, Q148HE138DA23V, V31I, M50L, A91S, T93S, L101I, T218S, D232N, S283DGB
 IN_1289IN_1289 RAL E138KT, G140S, Q148HL74LIMK7KR, E11D, S24SN, V31I, S119R, S123C, T124N, K156N, G163GE, T218I, L234IV, N254K, D256DEB
 IN_994IN_994 RAL G140S, Q148R K14R, V31I, K42KR, M50T, L63LV, L74I, K111T, T206S, D256DE, V259VIB
 IN_1619IN_1619 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_3281IN_3281 RAL G140S, Q148H E10D, V32I, L45V, L101I, T125A, K159KE, G163E, Y227F, D253H, D256EB
 IN_553IN_553 RAL G140S, Q148H S17N, M50ML, E87D, T112TA, T124N, T125A, M154I, V201VIB
 IN_254IN_254 RAL G140S, Q148H S17N, V31I, L101I, T112I, T124N, G163E, V201I, K211Q, I220V, D256EB
 IN_826IN_826 RAL G140S, Q148H S17N, S39C, L101I, T124A, K160Q, D167E, V201I, K244KR, S283GB
 IN_3175IN_3175 RAL G140S, Q148H E10D, E11D, A21AT, A91T, L101I, K111Q, T112TI, T124NB
 IN_128IN_128 RAL G140S, Q148H P30Q, S39N, I72V, L101I, T112A, S119P, V150A, V165I, D167E, H171Q, V201I, I220M, N222K, D232N, M275VB
 IN_1337IN_1337 RAL G140S, Q148H S17SN, V31I, L101I, S119SG, K156N, K173R, I203M, T206S, D207E, I208L, Y227F, D253YB
 IN_475IN_475 RAL G140S, Q148H S17N, M50ML, I72V, L101I, K111R, T124N, T125V, G163E, D167E, T218S, D256EB
 IN_352IN_352 RAL E138K, G140S, Q148H E11D, K14R, V32I, S39C, V88I, L101I, K103R, S119G, T122I, T125A, I200M, V201I, T206SB