<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation G140A
Rx >=1 INI
IncludeMixtures No
References 6
Patients 15
Isolates 15
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Garrido (2009)Pt01Pt01 RAL G140A, Q148R K14R, S24G, D25E, L45I, I113V, T124N, T125A, E157Q, K160S, V165VI, I220L, Y227F, L234V, D256EB
Brenner (2011)092810.002092810.002HQ423435RAL E138K, G140A, Q148K S17N, L28I, P30A, I60V, G106A, T115M, T124TN, I208M, D232N, D256EB
 1037910379_1HQ423444RAL E138EA, G140A, Q148R E10EQ, E11D, S24N, D25E, M50I, K111T, I203M, L234LV, V259VIB
Canducci (2011)Pt7Pt7W40JN163898RAL39G140A, Q148RG163RE10G, K14R, V79I, T125V, K156N, I208M, D232N, D256EB
Garrido (2012)BAA295958BAA295958JQ716866RAL52G140A, Q148R V31I, D41N, L101I, V201I, T206S, I268L, R269KB
 BAA295891BAA295891JQ716892RAL52G140A, Q148R K14R, S24G, D25E, L45I, I113V, T124N, T125A, E157Q, K160S, V165VI, I220L, Y227F, L234V, D256EB
de Souza Cavalcanti (2014)BRSP461BRSP461 RAL G140A, Q148R K14R, S17N, V31I, V32VG, S39R, V79I, L101I, S119G, T122I, T125A, P142SB
 BRSP17BRSP17 RAL G140A, Q148R E10D, V31I, M50I, V79I, L101I, K111T, S119T, T124Q, T125A, I135V, I203M, I208L, L234LV, V259VIB
Hurt (2014)IN_1916IN_1916 RAL G140A, Q148K S17N, N27H, V31I, E35Q, S39N, D41N, M50I, L101I, G163T, G193E, V201I, T218S, I220L, Y227F, L234VB
 IN_612IN_612 RAL E138A, G140A, Q148R K14R, L101I, S119P, T124A, K136T, P142T, I203M, I208M, T218S, Y227F, L234I, D256EB
 IN_946IN_946 RAL E138K, G140A, Q148K T112I, T122I, T124N, D256E, D278DG, R284G, D288NB
 IN_524IN_524 RAL G140A, Q148R D6E, E10D, E11D, V31I, M50T, V201I, T206S, L234I, R269KB
 IN_221IN_221 RAL G140A, Q148R E11D, V31I, V79I, T125V, E152EK, L158I, L234V, D286NB
 IN_849IN_849 RAL G140A, Q148R E11D, K111T, T124N, D167E, V201VI, I203IMB
 IN_2253IN_2253 RAL E138K, G140A, Q148K E11D, A21T, V31I, L45V, L101I, K111T, I113V, T125A, G163T, I203M, T218S, K219KT, D253E, D256E, D279GB