<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation E138D
Rx II-naive
IncludeMixtures No
References 13
Patients 19
Isolates 19
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Hierholzer (2002)EC003EC003AY173959None  E138DS17N, M50I, V77A, L101I, T124A, T125A, V201I, K215N, I220L, V259IB
de Sa Filho (2006)BREPM11931BREPM11931DQ085869None  E138DE10D, A21S, V31I, M50I, K71N, I72V, G106R, N117H, T125A, K156NB
 BREPM11932BREPM11932DQ085870None  E138D, V151IE10D, A21S, M50I, I72V, I113V, T125AB
Brennan (2008)851-30851-30EU618313None  E138DV31I, I72V, L101I, T124N, T206TS, Y227F, D256E, A265V, S283GB
Miura (2008)BEC5BEC5EU517861None  E138DS17N, M50T, T125A, V201I, K219T, I220LB
 BEC86BEC86EU517889None  E138DE11D, V31I, I60M, I72V, K173Q, S230N, D232E, A265V, D286NB
Brumme (2009)A2572A2572GQ371770None  E138DS17N, I72V, P90S, L101I, T124A, T125A, V201IB
 D4506D4506GQ371821None  E138D, P145PL, V151VLS17N, L28I, S39C, L101I, T124A, T125A, I135V, P142PS, V150A, K173KR, I220L, Y227FB
 M2511M2511GQ372005None  E138DS17C, L101I, T125A, Q216H, A265V, D286DNB
Garrido (2009)399INT-399GU217246None  E138DK14R, S17SC, L28I, P30PA, S39C, I60V, L101I, T124TA, T125AS, I135IV, K211R, I220IV, A265AVB
Low (2009)mdr13mdr13FJ786398None  E138DS17N, V32I, L101I, T112A, T124N, T125A, V165I, K211Q, E212AB
Passaes (2009)BR.RJ.FT14BR.RJ.FT14HM026775None  E138DD6N, E13D, V32I, K42R, L101I, T124N, T206S, D229E, R284GB
Rangel (2010)HIV264bHIV264bGU797536None  E138DL28I, V31I, S39C, L101I, V201I, T206S, K215N, D229EB
 HIV264pHIV264pGU797537None  E138DL28I, V31I, S39C, L101I, V201I, T206S, K215N, D229EB
Sanabani (2011)BR1055BR1055JN692454None  E138DE11D, K14R, A21T, I113V, T124S, T125A, S230N, L234V, S255N, V281MB
Garrido (2012)BAA295935BAA295935JQ716911None  E138DV32I, D41N, I72V, L101I, T122I, T124A, V201IB
Iamarino (2012)BF.BR.0709BF.BR.0709JN234050None  E138DS17N, K34R, M50L, I72V, L101I, K111Q, S119G, T124N, T206S, D207E, Y227F, D232E, D253Y, D256E, A265V, V281A, R284T, Q285PB
Reigadas (2013)55JX425473None  E138DE11D, M50I, I60V, I72V, K111T, S119G, T122I, V126M, T206S, I208MB
 212212JX425679None  E138DD3E, S17N, L101I, I113V, T124A, V201I, T218S, I220L, C280SB