<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation E138D
Rx >=1 INI
IncludeMixtures No
References 5
Patients 23
Isolates 27
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Sichtig (2009)Pt105150FJ183702RAL106Y143RL74M, T97A, E138DS17N, M22I, A23V, L28I, L45V, L101I, S119T, T218TS, L234LV, D256E, I268MB
Blanco (2011)JGG_03BLJGG_03BL RAL Y143RL74M, E138DV31I, T125V, D232EB
Molina (2012)32633263_2 RAL34 E138DK14R, S17SN, V31VI, I60M, I84ITM, L101I, T112V, T124A, I135IV, K188KR, V201I, A265V, R269RK, S283G, R284RG, D286DNB
  3263_3 RAL48 E138DK14R, S17SN, V31VI, I60M, L101I, T112V, T124A, I135IV, K188KR, V201I, A265V, R269RK, S283G, R284G, D286NB
  3263_4 RAL66G140S, Q148HE138D, R263RKK14R, S17N, V31VI, I60M, L101I, T112V, T124A, I135V, K188KR, V201I, A265V, S283G, R284G, D286NB
 30773077_2 RAL28 E138DV31I, M50I, T124N, T125A, D167E, V201I, A265V, D286NB
  3077_3 RAL54 E138DV31I, M50I, I72IV, T124N, T125A, D167E, V201I, A265V, D286NB
  3077_4 RAL88 E138DV31I, M50MI, I72IV, T124N, T125A, D167E, V201I, A265V, S283SG, D286DNB
de Souza Cavalcanti (2014)BRSP222BRSP222 RAL Y143RL74M, T97A, E138DE10D, V31I, M50I, L101I, T112V, S119P, T122I, T124N, T125A, I135V, E157Q, I203M, I208L, T218S, I220L, D253VB
 BRSP24BRSP24 RAL N155HE138D, V151IE10D, A21S, E170AB
 BRSP380BRSP380 RAL N155HE138D, V151IE11D, D25E, L28I, V37I, S39C, M50L, L74I, L101LF, T124A, E157Q, K160T, I203M, I208M, D232N, L234I, D253E, N254GB
Hurt (2014)IN_2034IN_2034 RAL N155HE138DI72V, T112I, T125V, D167EG, S195CB
 IN_1807IN_1807 RAL G140S, Q148HE138DK14KR, S17N, R20RK, M50L, I60IM, T112V, T124A, K156KN, T206S, K211R, T218S, V259VIB
 IN_376IN_376 RAL N155HE138D, V151IS17N, M50L, L101I, T124A, D167E, K188R, I220L, D232N, I251IL, A265V, R269RKB
 IN_3091IN_3091 RAL E92QL74M, E138DE11D, S24N, D25E, K211R, K215N, I220L, S230N, D256E, D278DNB
 IN_188IN_188 RAL G140S, Q148HE138DK7R, S39C, L101I, T124N, V201I, T210S, I220L, Y227F, S283GB
 IN_801IN_801 RAL N155HE138D, V151I, G163KS17N, V31I, M50I, L101I, T124N, V201IB
 IN_3310IN_3310 RAL N155HE138D, V151IS17N, V31I, T124N, T125A, V126L, I135IV, K136KT, K156N, V201I, T206S, D232N, D256EB
 IN_2322IN_2322 RAL N155HE138DD6E, P30S, L45Q, M50MI, I60V, L101I, I135V, V165VI, F181L, I203M, I208IM, I220IV, N254K, S255G, I268ILB
 IN_2527IN_2527 RAL N155HE138DS17N, A23T, L28I, L45Q, I72V, T93TP, T124N, K219N, N222K, D232N, D256E, S283GB
 IN_2378IN_2378 RAL N155HE138D, V151IK14R, R20K, V32I, L45I, L101V, K136Q, G163A, V201I, T206S, I220V, D232DNB
 IN_1868IN_1868 RAL G140S, Q148HE138DS17N, V31I, I72V, I113V, T124A, T125A, T206SB
 IN_2559IN_2559 RAL N155HL74LIM, A128T, E138D, V151IM50L, E157Q, K160Q, G163AB
 IN_1549IN_1549 RAL N155HE138D, V151IK14R, R20RK, N27NH, P30PA, V32I, L45LI, L101IV, K136Q, G163A, V201I, T206S, I220V, D232DN, I257IVB
 IN_1163IN_1163 RAL G140S, Q148HE138DA23V, V31I, M50L, A91S, T93S, L101I, T218S, D232N, S283DGB
 IN_942IN_942 RAL N155NHE138D, V151VIK7R, S17SN, L28I, S39C, M50I, T112M, T124N, T125A, V165I, V201I, Q216R, K219NB
 IN_332IN_332 RAL Y143RT97A, E138DE11D, S17C, L101I, K111KR, T112K, S119G, T122I, T124TN, T125A, T218SB