<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation E138A
Rx >=1 INI
IncludeMixtures No
References 5
Patients 17
Isolates 19
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Canducci (2009)pt6pt6w20EU908751RAL21E138AT97A, Y143KL101I, S119R, K156N, I208LB
  pt6w48EU908754RAL52E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, R224RGB
Brenner (2011)092204.055092204.055HQ423432RAL E138A E11D, V31I, L101I, T124N, S195T, I203M, K215N, K264RB
 092710.036092710.036HQ423433RAL E138A E11D, V31I, L101I, T124N, S195T, I203M, K215N, K264RB
Canducci (2011)Pt1Pt1W20JN163877RAL21E138AT97A, Y143KH16P, M22R, L101I, S119R, K156N, I208LB
  Pt1W48JN163879RAL43E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, G277RB
 Pt2Pt2W64JN163885RAL64E138A, Y143CL74M, T97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G272E, G277RB
de Souza Cavalcanti (2014)BRSP74BRSP74 RAL E138A, G140S, Q148HT97AS17N, I72V, L101I, S119R, K156N, K188R, V201I, K211R, I268L, D270NB
Hurt (2014)IN_601IN_601 RAL E138A, G140S, Q148H E11D, S24N, D41N, I72V, T112A, S119P, L234LFB
 IN_1901IN_1901 RAL E138A, G140S, Q148H D25E, P30S, S39C, T124N, T125AV, V201I, T206S, I220L, I251L, M275VB
 IN_612IN_612 RAL E138A, G140A, Q148R K14R, L101I, S119P, T124A, K136T, P142T, I203M, I208M, T218S, Y227F, L234I, D256EB
 IN_1456IN_1456 RAL E138A, G140S, Q148H S17N, S39SN, L101I, T124A, V165I, V201I, K211R, K219N, N222K, S230N, A265AV, I267IV, I268IL, K273Q, D278NB
 IN_1612IN_1612 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_1611IN_1611 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_914IN_914 RAL E138A, G140S, Q148H S17N, L45IT, L101I, T124A, T125A, V126VA, E157Q, K160Q, G163E, V165IB
 IN_1386IN_1386 RAL E138A, G140S, Q148H E11D, D25E, S39T, L45Q, I60IM, I84L, G94A, L101I, T124N, G163A, K188R, Y194C, V201I, N222K, S230N, I268L, R284RGB
 IN_1915IN_1915 RAL E138A, G140S, Q148H T124A, M154I, G193E, V201I, I208L, D278N, S283GB
 IN_1619IN_1619 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_33IN_33 RAL E138A, Q148H E10D, I72V, S123G, T124A, K127R, D232NB