<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation E138A
Rx >=1 INI
IncludeMixtures No
References 4
Patients 6
Isolates 8
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Canducci (2009)pt6pt6w20EU908751RAL21E138AT97A, Y143KL101I, S119R, K156N, I208LB
  pt6w48EU908754RAL52E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, R224RGB
Brenner (2011)092204.055092204.055HQ423432RAL E138A E11D, V31I, L101I, T124N, S195T, I203M, K215N, K264RB
 092710.036092710.036HQ423433RAL E138A E11D, V31I, L101I, T124N, S195T, I203M, K215N, K264RB
Canducci (2011)Pt1Pt1W20JN163877RAL21E138AT97A, Y143KH16P, M22R, L101I, S119R, K156N, I208LB
  Pt1W48JN163879RAL43E138A, G140S, Y143H, Q148H L101I, S119R, K156N, I208L, G277RB
 Pt2Pt2W64JN163885RAL64E138A, Y143CL74M, T97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G272E, G277RB
de Souza Cavalcanti (2014)BRSP74BRSP74 RAL E138A, G140S, Q148HT97AS17N, I72V, L101I, S119R, K156N, K188R, V201I, K211R, I268L, D270NB