<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation T125V
Rx >=1 INI
IncludeMixtures No
References 9
Patients 39
Isolates 44
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Baldanti (2009)PV8PV8GU350728RAL26  K7Q, L101I, T125V, I135V, M154L, V165I, K211R, D256EB
Garrido (2009)Pt06Pt06 RAL N155HG163KS17N, A38AV, L101I, T112I, T124A, T125V, E157Q, K160Q, K211R, D256EB
Blanco (2011)DCR_02BLDCR_02BL RAL G140S, Q148H A23V, V31I, T125V, D232E, A265VB
 JGG_03BLJGG_03BL RAL Y143RL74M, E138DV31I, T125V, D232EB
Brenner (2011)102001.076102001.076HQ423441RAL T66IT97A, G163RE11D, D25E, V31I, I60V, I72V, A91T, G106A, T112I, I113V, S119P, T124N, T125V, I203M, A205T, D256E, D278DYB
Canducci (2011)Pt7Pt716JN163897RAL13G140S, Q148R T125V, K156N, I208M, D256EB
  Pt7W40JN163898RAL39G140A, Q148RG163RE10G, K14R, V79I, T125V, K156N, I208M, D232N, D256EB
  Pt7W64JN163899RAL65G140S, Q148HG163RK14R, V79I, T112A, T125V, K156N, I208M, D256EB
Garrido (2012)BAA295956BAA295956JQ716865RAL52Y143RL74MK7R, V31I, L101I, T112I, T125V, K219N, N222KB
 BAA295862BAA295862JQ716884RAL52  R20K, I72V, L101I, I113L, T124N, T125V, I204V, T206SB
 BAA295867BAA295867JQ716886RAL52  S17N, A23AV, V31I, I72V, K103R, T112I, T124N, T125V, K156N, V201I, T206S, S283GB
Molina (2012)33263326_2 RAL42G140S, Q148H E11D, S24N, K34R, I72IV, I84M, A91T, L101I, T125V, I161T, V201I, K211KR, S230N, V260L, P261F, S283GB
  3326_3 RAL48G140S, Q148H E11D, S24N, K34R, I72IV, I84M, A91T, L101I, T125V, I161IT, V201I, K211R, S230N, S283GB
 32523252_2 RAL16  V31I, P90PS, L101I, T112I, T124A, T125V, I135V, G163QH, A179G, F181L, V201I, T206TS, L234I, D256DE, A265V, D270DHB
  3252_3 RAL33  V31I, K46KR, L101I, T112I, T124A, T125V, I135V, G163QH, A179G, F181L, V201I, T206S, L234I, D256E, I268L, D270HB
 41564156_3 EVG90  D6E, S17N, V31I, I84IM, T112TIAV, T124N, T125V, G163GE, D232E, D256DE, A265AVB
 30533053_2 RAL12  V31VMI, T124TN, T125V, K156N, D167EB
  3053_3 RAL40  V31I, T124TN, T125V, K156N, D167EB
de Souza Cavalcanti (2014)BRSP332BRSP332 RAL N155HT97A, V151I, G163RS17N, V31I, I72V, S119R, T124A, T125V, K156N, V165I, Q168R, V201I, R224Q, D256E, R269K, V281M, S283GB
 BRSP75BRSP75 RAL Y143R E11D, S24N, V31I, T112TA, I113IV, S119T, T124N, T125V, I203IM, K219N, I220L, N222KB
Hurt (2014)IN_2034IN_2034 RAL N155HE138DI72V, T112I, T125V, D167EG, S195CB
 IN_1429IN_1429 RAL G140S, Q148H L101I, T124A, T125V, T206S, I208L, K215N, I220IL, Y227YF, N254K, S255G, I268L, R269K, D270H, S283GB
 IN_633IN_633 RAL G140S, Q148H M50I, I72V, S119P, T122I, T124A, T125V, G163AE, D256E, S283GB
 IN_443IN_443 RAL E92Q, N155HE138EDS17N, I72V, T112I, T124A, T125V, T206S, D232DN, D279DGB
 IN_2227IN_2227 RAL E92EQ, N155NHA128ATE10D, V31VI, M50MI, T125V, K156KN, V165I, D256EB
 IN_1185IN_1185 RAL G140S, Q148H E11D, V31I, V37I, L63I, L101I, K111T, S119T, T124N, T125V, I135V, V201I, S283GB
 IN_634IN_634 RAL G140S, Q148H M50I, I72V, S119P, T122I, T124A, T125V, G163AE, D256E, S283GB
 IN_1402IN_1402 RAL G140S, Q148H K7R, R20K, V31I, I60V, I72IV, E96D, L101I, T112I, T124N, T125V, I135V, I182V, V201I, I203M, Q216H, D256EB
 IN_947IN_947 RAL Q148QR S17N, M50MI, L101I, T112I, T124N, T125V, G163E, D232N, D256EB
 IN_1441IN_1441 RAL N155NH K7R, K111KR, T124S, T125V, K160KN, K264KRB
 IN_505IN_505 RAL Y143YCG163EK, S230SRS17N, L101I, T124A, T125V, T218S, L234LF, S255SRB
 IN_167IN_167 RAL E138K, Y143YCHR, Q148QR V31I, L45V, C56Y, I72V, T125V, D167E, K188R, C280CGB
 IN_3174IN_3174 RAL T66TAIV S17N, V31VIM, I72IV, P90ST, A91AV, L101I, K111T, T124NS, T125V, I135IV, V165I, V201I, S230N, D256EB
 IN_2914IN_2914 RAL N155HV151I, G163GRD6E, S17N, I72IV, A80S, L101I, T112TA, T124N, T125V, G193E, E212A, N254NKB
 IN_852IN_852 RAL T66TI, Y143YC S17N, V75VI, L101I, T124N, T125V, I135V, G163E, E170EA, I208LB
 IN_760IN_760 RAL G140S, Q148H M50I, I72V, S119P, T122I, T124A, T125V, G163AE, D256E, S283GB
 IN_221IN_221 RAL G140A, Q148R E11D, V31I, V79I, T125V, E152EK, L158I, L234V, D286NB
 IN_1409IN_1409 RAL Y143R, N155NHQ95KD6E, E11D, V31I, V32I, V37I, S39N, L101I, S119ST, T124A, T125V, V201I, T206S, D207E, N222K, Q252QR, C280SB
 IN_2331IN_2331 RAL N155NHE138ED, Y143YS, V151VI, G163K, S230SRS17N, L45LV, L101I, T124A, T125V, I135V, D256EB
 IN_1309IN_1309 RAL G140S, Q148H K7R, S17N, I72V, L101I, T124TA, T125V, I220L, R224Q, L234I, V259VI, D270N, S283GB
 IN_68IN_68 RAL G140S, Q148H M50I, T125VB
 IN_727IN_727 RAL S147G, Q148RH114YE11D, V31VIM, I113V, T124N, T125V, L158V, S195TB
 IN_2865IN_2865 RAL E138EK, Q148QR, N155NHV151VI, G163EKV31VI, M50I, L101I, T124TA, T125V, F181L, I182V, V201I, T218S, I220M, Y227YF, D232DN, D256EB
 IN_475IN_475 RAL G140S, Q148H S17N, M50ML, I72V, L101I, K111R, T124N, T125V, G163E, D167E, T218S, D256EB