Integrase Inhibitors

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Integrase Inhibitors

Subtype	B
Gene	IN
Mutation	T125S
Rx	II-naive
IncludeMixtures	No

References	17
Patients	26
Isolates	27

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	INIs	INIMajorDRMs	INIMinorDRMs	OtherMut	Subtype
Graf (1998)	RL42	RL42	U71182	None		N155D	S17C, S119R, T124N, T125S, K211R, D229G, A265V	B
Tovanabutra (2001)	NP1623	NP1623	AF362994	None			E11D, S17C, A91T, L101I, S119R, T125S, V165I, K211R, S230N, L241P, A265V	B
Su (2003)	02HNsc11	02HNsc11	AY275556	None		L68I	A91T, L101I, K111R, S119R, T124N, T125S, K156N, V165I, Y194T, S195C, K211R	B
Swanson (2003)	TH1600	TH1600	AY214058	None			S17C, S119R, T124N, T125S, G163E, K211R, I220V, K236KR, A265V	B
Takebe (2003)	TY_pat4	TYmSTD101	AB097870	None			D6E, E11D, S17C, V31I, A91T, L101I, S119R, T124N, T125S, I162V, G163E, K173E, K188E, K211R, S230N	B
	TY_pat9	TYmIDU502	AB097865	None			D6X, S17N, E35G, T112I, S119R, T124N, T125S, G163E, K211R	B
Liu (2005)	02HNsc11	02HNsc11	DQ007903	None		L68I	A91T, L101I, K111R, S119R, T124N, T125S, K156N, V165I, Y194T, S195C, K211R	B
Qiu (2005)	YNRL9828	YNRL9828	AY967805	None			S17C, K71N, S119R, T124N, T125S, V165I, K211R, L234I, R269K, K273T, D278A, S283G	B
	YNRL9607	YNRL9607	AY967804	None			S17C, S119R, T124N, T125S, K211R, S230N, L234I, A265V	B
Tee (2006)	KL019	04_019.1	DQ366665	None			A91T, S119R, T125S, L234I	B
Watanaveeradej (2006)	00TH_C3198	00_C3198	AY945710	None			A91T, S119R, T124N, T125S, F185Y, K211R	B
Brumme (2009)	INT_3474	INT_3474	FJ812925	None			E11D, L101I, K111T, S119P, T122I, T124TA, T125S, T218TS, D256E	B
	INT_3787	INT_3787	FJ813238	None			K7Q, V31VI, I72V, K111T, S119P, T122I, T124A, T125S, V201I, S230SN	B
Garrido (2009)	68	INT-68	GU216915	None			A33AG, M50I, C56CW, K111T, S119R, T125S	B
	113	INT-113	GU216960	None			L28I, V37I, L101I, S119P, T122I, T125S, S230N, D256E	B
	215	INT-215	GU217062	None			E11D, S24A, V31I, A91T, L101I, S119R, T125S, T206S, I208L, T210S, K211S, E212I, T218S, D232E, D256E	B
Sichtig (2009)	720	720	FJ183498	None			L101I, T112I, I113V, S119P, T122I, T124A, T125S, I135IV, V201I	B
van Hal (2009)	W38	W38	FJ554711	None			V31I, I72V, L101I, T112I, S119G, T122I, T124A, T125S, G193E, V201I, L234V, R269K, D278N	B
	W55	W55	FJ554728	None			E10D, E13D, V31I, S39N, S119T, T124A, T125S, K188R, G193E, V201I, A265V	B
	W127	W127	FJ554800	None			R20K, V31I, I72V, L101I, T112I, S119G, T122I, T124A, T125S, G193E, V201I, L234V, R269K, D278N	B
Rangel (2010)	HIV268b	HIV268b	GU797541	None			S119R, T125S, D253E, D256E	B
Brenner (2011)	7651	7651	HQ207760	None			E11D, V31I, L101I, K111T, S119P, T122I, T124A, T125S, V201I, I203M, I208M, D256E	B
Kijak (2012)	05TH429730	05TH429730	JN248347	None			K71Q, S119R, T125S, F181L, I203M, K211R, S230N, A265V	B
	05TH440248	05TH440248	JN248348	None			S17N, L28I, G70E, L101I, T112M, S119R, T124N, T125S, K211R	B
	04TH601066	04TH601066	JN248329	None			V31I, I89M, L101I, S119R, T124N, T125S, K156N, E157Q, K160T, S230N	B
	04TH808998	04TH808998	JN248335	None			K14R, A91T, I113V, S119R, T125S, S195N, K211R, R231K, L234V, Q285QR	B
Rolland (2012)	AA040a_WG13	AA040a_WG13	JX447158	None	E138K	T97A	G70E, L101I, S119R, T124N, T125S, M154I, K211R	B

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