<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype B
Gene IN
Mutation T125A
Rx >=1 INI
IncludeMixtures No
References 22
Patients 251
Isolates 329
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Charpentier (2008)Pt1Pt1-W4 RAL4Q148R E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
  Pt1-W8 RAL8Q148R E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, V259I, D278EB
  Pt1-W11 RAL11G140GS, Q148QH, N155NH E11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
  Pt1-W22 RAL22G140GS, Q148QH E11D, A21T, A23AV, D25E, L101LF, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D256DE, D278EB
  Pt1-W39 RAL39G140GS, Q148QH E11D, A21T, A23AV, D25E, L101LF, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D256DE, D278EB
Malet (2008)1bH-SH1-W8FJ538990RAL8Q148R, N155H E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
  H-SH1-W16FJ538991RAL15G140S, Q148H E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
 1cSH2-W10FJ538988RAL11G140S, Q148H S17N, L28I, S39C, S119P, T122I, T124A, T125AB
 H1H1-W12FJ538974RAL13N155H L2W, K7R, R20K, V31I, L101I, T112V, T124A, T125A, F181L, V201I, K219N, N222KB
 H6H6-W20FJ538984RAL20N155HT97A, V151IE11D, V31I, L101I, K111T, I113V, S119T, T124N, T125A, S195C, A196P, A205T, T218S, D232NB
 HSH2H-SH2-W12FJ538993RAL16N155H S17N, R20K, L28I, S39C, T124A, T125A, V201I, I208LB
  H-SH2-W22FJ538994RAL22G140S, Q148HG163RS17N, R20K, L28I, S39C, G70R, T124A, T125A, V201I, I208LB
Baldanti (2009)PV4PV4GU350730RAL4  E10D, L101I, S119P, T122I, T125A, V165I, V201I, I208L, K215N, D256EB
Canducci (2009)pt1pt1w4EU908743RAL4  S17N, S24N, I113V, S119T, T124A, T125A, V165I, T206S, Q216HB
  pt1W12EU908744RAL13  S17N, S24N, I113V, S119T, T124A, T125A, V165I, T206S, Q216HB
  pt1w24EU908745RAL26Y143R S17N, S24N, I113V, S119T, T124A, T125A, V165I, T206S, Q216HB
  pt1w48EU908746RAL39Y143R S17SN, S24N, I113V, S119T, T124A, T125A, V165I, T206S, Q216HB
 pt3pt3w4EU908756RAL4 V54IV31I, I113V, T124A, T125A, V201I, K215NB
  pt3w12EU908757RAL13 V54IV31I, I113V, T124A, T125A, V201I, K215NB
  pt3w24EU908758RAL26G140S, Q148HV54IV31I, I113V, T124A, T125A, V201I, K215NB
 pt4pt4W4EU908760RAL4 R263KD3Q, G70E, L101I, S119R, T124N, T125A, M154L, V165I, K211R, Q252X, D256E, R262EB
  pt4W12EU908761RAL13  D3Q, G70E, L101I, S119R, T124N, T125A, M154L, V165I, K211R, D256EB
  pt4W24EU908762RAL26Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  pt4w32EU908763RAL35Y143CT97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211KR, D256EB
  pt4w36EU908764RAL39Y143CL74M, T97AD3Q, L101I, S119R, T124N, T125A, M154L, V165I, K211R, D256EB
 pt7pt7w4EU908766RAL4  S24A, L101I, T112TI, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
  pt7w8EU908767RAL8  S24A, L101I, T125A, I135V, F181L, T206S, D229E, S230N, D256DEB
  pt7w12EU908768RAL13  S24A, L101I, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
  pt7w20EU908769RAL21  S24A, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
  pt7w24EU908770RAL26  S24A, L101LI, T125A, I135V, F181L, T206S, D229E, S230N, D256EB
 pt5pt5w24EU908775RAL26N155NHV151IK14R, M22L, V32I, V37I, S39C, L101I, T125A, G163Q, E170Q, V201I, D253EB
Delelis (2009)Pt1Pt1 RAL48Y143R V32I, S39C, K111R, T124N, T125A, G193E, N254KB
 Pt3Pt3 RAL16Y143R I113V, T124NS, T125A, T206S, I220L, Y227FB
Garrido (2009)Pt01Pt01 RAL G140A, Q148R K14R, S24G, D25E, L45I, I113V, T124N, T125A, E157Q, K160S, V165VI, I220L, Y227F, L234V, D256EB
 Pt03Pt03 RAL Y143RT97AH12HN, V31I, K111T, S119T, T125A, V126L, I135V, P142A, I203M, I208L, D256EB
 Pt18Pt18 RAL   E10A, E11D, S24N, I113V, S119SG, T122I, T124N, T125A, I220LB
Sichtig (2009)Pt075163FJ183699RAL62N155HQ146QKE11D, K14R, A21T, A23V, V88I, I113V, S119P, T124N, T125A, Q177R, T206SB
 Pt013-KoelnFJ183691RAL31G140GA, Q148QR S119G, T122I, T125A, V201I, K215NB
  4786FJ183692RAL47Y143RL74M, T97AE11D, R20K, V31I, H51HR, S119G, T122I, T125A, V201I, K215NB
 Pt025068FJ183700RAL35G140S, Q148HG163KS17N, R20K, L28I, S39C, L45V, I113V, T124N, T125A, V201I, V259IB
  5864FJ183701RAL79G140S, Q148HG163EKQS17N, R20K, L28I, S39C, L45V, I113L, T124N, T125A, V201IB
 Pt044833FJ183697RAL41N155HV151VI, G163GRS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
  4951FJ183698RAL50N155HV151I, G163RS17N, V31I, T112V, T124N, T125A, V126L, S230N, D256EB
Wittkop (2009)11_M6GU358379RAL25G140S, Q148H E10D, R20K, V32I, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, Q221S, N222KB
  1_M9GU358380RAL39E138EA, G140S, Q148H E10D, R20K, V32I, L45LI, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, Q221S, N222K, V259VIB
  1_M12GU358381RAL52E138EA, G140S, Q148H E10D, R20K, V32VI, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, Q221S, N222K, V259VIB
 77_M3GU358385RAL12N155H S17N, I72V, L101I, S119G, T122I, T125A, A169S, T218S, I220L, Y227FB
  7_M6GU358386RAL25Y143YCHRT97TA, G163GRS17N, I72V, L101I, S119G, T122I, T125A, A169S, T218TS, I220L, Y227FB
  7_M9GU358387RAL39Y143YCHRT97TA, G163GRS17N, I72V, L101I, G106GA, S119G, T122I, T125A, A169FS, F185FL, S195SN, A196AT, T218TS, I220L, Y227FB
 66_M3GU358398RAL12Y143CL74LM, Q95QK, V151VI, S230RK7KR, S17N, V31I, T97TP, K111T, I113V, T124Q, T125A, A169AV, G189GV, I203MB
  6_M6GU358399RAL26Y143YCL74LMK7KR, S17N, V31I, K111T, I113V, T124Q, T125A, G189R, I203M, D279DA, S283SGB
Hatano (2010)4Virus15GU121691RAL Y143RT97AK7R, S17N, V31I, L101I, T112A, T125A, M154I, V201IB
  Virus16GU121692RAL Y143RT97A, G163GRK7R, S17N, V31I, L101I, T112A, S119T, T125A, M154I, V201VIB
 18Virus19GU121695EVG   K7R, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
  Virus91GU121767EVG   K7R, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203IM, I208L, L234IB
  Virus94GU121770EVG E92Q K7KR, D41DN, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234IB
  Virus95GU121771EVG E92Q, Q148QRL74LMK7KR, D41DN, I72IV, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234IB
  Virus97GU121773EVG E92QL68LV, L74LMK7KR, D41DN, I72IV, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234IB
 17Virus99GU121775EVG E138K, S147G, Q148R K7KR, I72V, V79VI, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
  Virus100GU121776EVG E138K, S147G, Q148RV54VIK7KR, I72V, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
  Virus103GU121779EVG E138K, S147G, Q148RV54VIK7KR, E35EQ, I72IV, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
  Virus20GU121696EVG E138K, S147G, Q148RV54IK7KR, E35EK, I72V, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234IB
 12Virus101GU121777RAL Y143YCT97A, S230RG4GR, R20K, T112V, I113V, T125A, H171Q, Y194YH, I200M, I203MB
  Virus122GU121798RAL Y143YCT97TA, S230SRR20K, T112V, I113V, T125A, H171Q, I200M, I203IMB
  Virus139GU121815RAL Y143YCL74LM, T97TA, S230SRR20K, T112V, I113V, S119ST, T125A, H171Q, I200M, I203IM, T218TSB
 11Virus104GU121780RAL G140GS, N155HA128AT, V151VIE10DG, E11D, V31I, S119P, T122I, T125A, V126M, G163E, S195C, L234V, D279DNB
Blanco (2011)CA4825CA128619 RAL21N155HG163KE11D, S24N, V31I, L101I, I113V, S119P, T122I, T124N, T125A, V201I, K211KRB
 CA5016CA128616 RAL29  S119G, T122I, T125A, M154L, I203M, L234I, D256EB
 CA25689CA128612 RAL27  E11D, A21T, V77A, S119P, T122I, T125A, D232E, L234HB
 ACM_09BLACM_09BL RAL N155H E10D, S119G, T122I, T124N, T125A, M154I, K211RB
Brenner (2011)INT3INT3_1HQ207824RAL   E11D, S24N, V31I, L45V, I72V, T112V, S119P, T122I, T125A, I203IM, K215NB
 1112211122HQ423448RAL   M50I, E96D, T112V, H114HP, S119R, T125A, I141IVB
Canducci (2011)Pt2Pt2W24JN163881RAL26Y143CT97AL101I, S119R, T124N, T125A, M154L, V165I, D256E, G277CB
  Pt2W36JN163882RAL35 L74M, T97A, Y143GL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277CB
  Pt2W37JN163883RAL36 L74M, T97A, Y143GI36V, L101I, S119R, T124N, T125A, M154L, V165I, D256EB
  Pt2W56JN163884RAL55Y143RT97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G277RB
  Pt2W64JN163885RAL64E138A, Y143CL74M, T97AL101I, S119R, T124N, T125A, M154L, V165I, K211R, D256E, G272E, G277RB
 Pt3Pt3W24JN163887RAL26Y143R S17N, S24N, I113V, S119T, T124A, T125A, V165I, V201I, T206S, E212K, Q216HB
 Pt4Pt4W24JN163889RAL26G140S, Q148HV54IV31I, I113V, T124A, T125A, V201I, K215N, G277CB
 Pt10Pt10w20JN163905RAL21Q148R S24N, L74I, L101I, T125A, V201I, Q216HB
  Pt10w28JN163906RAL30G140S, Q148H S24N, L101I, T125A, V201I, Q216HB
  Pt10w32JN163907RAL35G140S, Q148H S24N, D41N, L74I, A91T, L101I, T125A, V201I, Q216H, N254SB
Armenia (2012)PT_141PT_141_MO_6JN544113RAL N155HV151I, G163GRD6T, K7E, E11D, K14R, V31I, M50I, I72IV, I113V, S119SR, T125A, V201I, D256E, V281VMB
DeJesus (2012)72997299_2 EVG32G140C, Q148R K14R, S17N, K34R, G59E, S119P, T124N, T125A, H183HP, V201I, S230N, D256EB
Fransen (2012)pt3pt3 RAL G140GS, Q148QHR, N155NHV151IE11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278EB
Garrido (2012)BAA295871BAA295871JQ716889RAL52  E11D, F26Y, V31I, I60V, I72IV, T112I, T124N, T125A, V126M, G193R, I203M, Q216H, K219QB
 BAA295891BAA295891JQ716892RAL52G140A, Q148R K14R, S24G, D25E, L45I, I113V, T124N, T125A, E157Q, K160S, V165VI, I220L, Y227F, L234V, D256EB
 BAA295905BAA295905JQ716898RAL52G140GS, Q148QH E10D, V31I, I72V, L101I, S119G, T122I, T125A, K156N, V201I, T206S, Q216H, Q221R, D256EB
 BAA295915BAA295915JQ716902RAL52  D6E, L28I, V37I, S39C, I84IM, L101I, T124A, T125A, I135VB
Molina (2012)33823382_2 RAL34  S17N, V31I, L101I, K103R, T124S, T125A, E198D, I200IL, V201I, T206S, D232E, A265VB
  3382_3 RAL40Y143YRHC, N155NH S17N, V31I, L101I, T122TI, T124S, T125A, I135IV, E198D, V201I, T206S, D232E, A265VB
 41124112_2 EVG12  K14R, V31I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234I, S255N, D256E, S283GB
 34043404_2 EVG56  P30PL, L101LI, A105AT, K111TA, S119G, T122I, T125A, V201IB
 42044204_2 EVG91  E11D, V32VI, V37I, S39SC, D41DN, I60V, S119G, T122TI, T124N, T125A, V201I, I203MB
 33253325_2 RAL81  R20RK, V31I, E48EK, L101I, I113IV, S119ST, T125A, M154L, K173R, F181L, G193E, T206S, T210I, T218I, I220V, L234H, D279GB
 34803480_2 RAL19  S17N, V31I, I60L, T124N, T125A, K173KR, V180VI, I182V, K215KN, Y227F, D253Y, D256E, D278EB
 34713471_2 EVG8T66TI, E92EQ K14R, S17SN, R20RK, V31I, D41DN, L101I, T112V, T124A, T125A, G134N, I135V, K136T, R187RK, T206S, L234I, V249VI, S283GB
 32773277_2 RAL19 A128TE11D, E13D, M50L, L101I, K111T, T125A, Y227F, S230N, L241LF, D256E, A265VB
 32403240_2 EVG41  S17SN, L45V, I89L, L101I, K111R, T112I, T124N, T125A, I203M, T206S, D256EB
 40274027_2 EVG24 L68VE11D, V31VI, V32VI, D41DN, M50MT, I73V, T112TA, T125A, I135V, V201I, R284GB
 32983298_1 RAL52  R20RK, V31I, T112A, T124S, T125A, K127KR, V165I, A205S, E287EKB
  3298_2 RAL64E92EQ V31I, T112AV, T124S, T125A, K127KR, V165I, A205SB
  3298_3 RAL84  V31I, T112A, T124S, T125A, K127KR, V165I, A205SB
  3298_4 RAL104  V31I, G70GE, T112TIAV, T124S, T125A, K127KR, V165I, K188KR, A205SB
 30623062_2 EVG12E92EQ D6E, E11D, S17N, V31I, L63I, L74I, E96D, L101I, T112V, T124N, T125A, G134N, K136T, E157Q, K160N, V201I, T206S, T210TI, K211R, L234I, R269K, S283G, D288NB
  3062_3 EVG25E92EQ, G140GA, Q148QRL68LVD6E, E11D, S17N, V31I, L63I, L74I, E96D, L101I, T112V, T124N, T125A, G134N, K136T, E157Q, K160N, V201I, T206S, T210TI, K211R, L234I, R269K, S283G, D288NB
 32783278_2 RAL26  A23V, S39C, L101I, T124N, T125A, I135V, D167E, F181L, V201I, K215N, D270NB
  3278_3 RAL44  K7R, S39C, D41DN, I72IV, A80AV, L101I, T124N, T125A, I135V, D167E, F181L, V201I, K215N, T218TAB
 32673267_2 EVG63  E11D, V31I, V37I, L101I, I113L, T124N, T125A, V201I, D288XB
  3267_3 EVG85  E11D, V31I, V37I, L101I, I113L, T124N, T125A, V201I, D288XB
 31023102_2 RAL38  K14R, D25E, K34R, M50MI, I72IV, I84IM, F100Y, L101I, T112V, S119T, T124A, T125A, K136Q, V201I, T218I, L234I, D256DE, D278A, S283GB
 34793479_2 EVG8  K7KR, E48EG, G94GR, T112A, T125A, F181FL, A196AV, E212A, Q216H, T218S, K219NB
  3479_3 EVG16  T112A, T125A, F181FL, V201VI, E212A, Q216H, T218S, K219NB
 32503250_2 RAL13  S17N, M50I, L63LM, I113IV, T124A, T125A, K215N, I220L, D279DGB
  3250_3 RAL24  S17N, M50I, L63M, T124A, T125A, K215N, I220L, L241LFB
 41474147_2 RAL98G140S, Q148H V31I, K111T, S119G, T122I, T125A, Q164QP, Q168QP, H171HP, R231K, D288NB
 42514251_2 RAL76  M50I, D55G, V75I, I84M, Q95QR, S119P, T125A, M154L, D167E, V201I, K211R, T218IB
 33673367_2 EVG94  S17SN, V31I, T115TA, T124N, T125A, A205AS, T206TS, D207DE, D232E, L234I, D253E, D256EB
 32023202_2 RAL15  S17N, K111KR, T125A, G193E, V201I, D232E, D286NB
  3202_3 RAL42  S17N, L101LV, K111KR, T125A, G193E, V201VI, D232E, D286NB
  3202_4 RAL67  S17N, I72IV, K111KR, T125A, G193E, V201I, D232E, D286NB
 31983198_2 EVG17  E10D, T124A, T125A, I135IV, K156N, V201I, I220V, D286DNB
  3198_3 EVG41  E10D, T124A, T125A, I135IV, S153SF, K156N, V201I, I220VB
  3198_4 EVG48  E10D, T124A, T125A, I135IV, K156N, V201I, I220VB
  3198_5 EVG55  E10D, T124A, T125A, I135IV, K156N, V201I, I220VB
 30563056_2 EVG19E92Q S17N, K34R, K46KR, M50L, T124A, T125A, V201I, A205S, T206S, I208L, K211RG, E212AB
  3056_3 EVG24E92QH51HYS17N, K34R, M50L, T124A, T125A, V201I, A205S, T206S, I208L, K211R, E212AB
 40964096_2 RAL20  D6E, K7KR, S17N, L74I, L101I, T124A, T125A, G163D, R187K, K188KR, K211T, E212A, Q221SB
  4096_3 RAL48  D6E, K7KR, S17N, L74I, L101I, T124A, T125A, G163D, R187K, K188KR, K211T, E212A, Q221SB
 30383038_2 EVG13  S39C, G59E, T124N, T125A, V126L, M154L, V201I, P233PS, L234LFB
  3038_3 EVG48  S39C, G59E, T124N, T125A, V126L, M154L, K173KR, V201IB
  3038_4 EVG56  S39C, G59E, T124N, T125A, V126L, M154L, V201IB
 41544154_2 EVG16  E11D, V31VI, L101I, K111T, T112IV, S119TP, T125A, V126A, V150A, V201IB
 31403140_2 RAL24 Q95QKK14R, S17N, V31I, L45LS, M50MI, C56Y, K71KR, L101I, T124S, T125A, I135V, K160Q, T218S, I251LB
  3140_3 RAL72  K14R, S17N, A23AV, V31I, C56Y, L101I, T124S, T125A, I135V, K160Q, H171HY, V180VI, T218TS, I251LB
 33633363_2 RAL16  K14KR, D41DN, L45Q, L101I, T125A, F181L, V201I, K219N, N222K, S283GB
 34173417_2 EVG12 V54IK14KR, S17SNYC, M50I, E96D, L101I, T112RS, T124N, T125A, I208IV, D288XB
  3417_3 EVG32 V54IK14KR, S17SNYC, M50I, E96D, L101I, T112RS, T124N, T125A, K211KT, S230SN, D288XB
 31333133_2 RAL71G140S, Q148H S24G, D25E, L28I, E35Q, L45V, T125A, V201I, S230N, S283R, R284GB
  3133_3 RAL81G140S, Q148H S24G, D25E, L28I, E35Q, L45V, T125A, V201I, S230N, S283R, R284GB
 30773077_2 RAL28 E138DV31I, M50I, T124N, T125A, D167E, V201I, A265V, D286NB
  3077_3 RAL54 E138DV31I, M50I, I72IV, T124N, T125A, D167E, V201I, A265V, D286NB
  3077_4 RAL88 E138DV31I, M50MI, I72IV, T124N, T125A, D167E, V201I, A265V, S283SG, D286DNB
 34653465_2 EVG12  E10D, A38AV, I84IV, T124N, T125A, I135IV, I141IT, M154I, D202DG, D207DNB
  3465_3 EVG36  E10D, T124N, T125A, I135IV, M154I, V201VIB
 33903390_2 RAL25  S17SN, A21AT, G59A, L101I, T124S, T125A, K136N, V201I, I203M, L234LF, L241LP, A248AT, I251IL, S255SRB
 33683368_2 RAL12  T124A, T125A, I135V, D167E, R284GB
  3368_3 RAL22  T124A, T125A, I135V, D167E, A265AV, R284RGB
 33523352_2 RAL32  L101I, V110VI, T124A, T125A, M154I, H171Y, R187K, T206S, K211RB
 40304030_2 RAL75  K14R, V31I, I60IM, G106A, T112I, T124A, T125A, G134D, K136Q, D167E, V201I, L234I, S283SGB
 30603060_2 EVG64T66I, Q148QR T112A, T125A, V126L, M154I, L234IB
 33893389_2 RAL13  D6E, E10D, I72IV, A91AS, S119G, T122I, T124A, T125A, I220L, Y227F, L234IB
  3389_3 RAL106 L74LM, T97A, V151VID6E, E10D, A91S, K103KR, S119G, T122I, T124A, T125A, I220L, Y227F, L234IB
 41734173_2 EVG43 T97AK14R, R20K, V31I, L101I, T112IV, T124A, T125A, G134N, I135V, G163Q, G193E, V201I, T206S, T218TI, Y227YF, L234I, S255N, D256E, D279G, S283GB
 30303030_2 EVG65  S17N, D25DE, N27NS, G59GE, I72IV, V77VI, V79VI, I84IM, V88VI, L101I, S119T, T124S, T125A, T206SB
 40104010_2 RAL25 L74M, T97AD6DN, E10D, S39SG, M50I, L101I, T112I, S119P, T124A, T125A, I135L, T206S, D279NB
  4010_3 RAL40 G163GRE10D, M50I, L101IV, T112I, S119P, T124A, T125A, K136KE, T206S, R269RK, D279DN, D288DNB
 30613061_2 EVG12  E10D, S24A, V31VI, L101I, K111T, S119T, T124TA, T125A, N144H, K160R, K188R, G193E, D279G, D286NB
  3061_3 EVG105  E10D, S24A, L101I, K111T, S119T, T124TA, T125A, K160R, K188R, G193E, D279G, D286NB
 40684068_2 EVG88  S17N, I84L, T112I, T124S, T125A, V201I, I203M, L234I, D256E, A265VB
 31683168_2 EVG66  E11D, S24N, V31I, K71KT, I72IV, L101I, S119P, T122I, T125A, R187RK, V201I, I220L, D232EB
  3168_3 EVG88  E11D, S24N, V31I, I72IV, L101I, S119P, T122I, T125A, V201I, I220L, D232EB
 40874087_2 EVG29  K14R, S24NT, M50MI, L74I, T112IV, T124N, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, D279DG, S283G, R284G, D286NB
 42534253_2 RAL29  K7R, D25E, M50MR, P90PS, F100Y, L101I, T112V, T124A, T125A, K136Q, V165I, V201I, T218I, K219Q, L234I, S255G, R269K, D278A, S283GB
 31593159_2 RAL19  E11ED, S17C, R20RG, M50MI, S119P, T124N, T125A, V126L, I182V, T206SB
  3159_3 RAL44  E11ED, S17C, M50MI, S119P, T124N, T125A, V126L, I182V, T206SB
Parczewski (2012)307307_18KC409156RAL196N155H E10D, L101I, T112I, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278GB
  307_xKC409158RAL201N155H E10D, L101I, T112I, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278GB
Sax (2012)66676667_2 EVG48E92Q M50I, T125A, I135V, M154I, I162V, V201I, K215N, L234IB
 66486648_2 EVG16E92Q K14R, R20K, S24N, D25E, V31I, G59E, I60V, L101I, T124A, T125A, D167DE, K215R, N222KB
Souza Cavalcanti (2012)BRSPBR10SP296JQ797733RAL130E138K, G140C, Q148RV54IE11D, V31I, V32I, V37I, D41N, V79I, L101I, T125A, K136Q, V201I, T206S, L234V, D270EB
de Souza Cavalcanti (2014)BRSP526BRSP526 RAL G140S, Q148H K7Q, R20RK, L63V, S119P, T122I, T124A, T125A, V165VI, K219N, N222K, S283SGB
 BRSP54BRSP54 RAL   S17N, I72V, I84M, N117T, T124A, T125A, M154I, V201I, Q221NB
 BRSP287BRSP287 RAL G140S, Q148HT97AK14KR, R20K, G70E, L101I, T112V, S119R, T124S, T125A, V201I, D232NB
 BRSP461BRSP461 RAL G140A, Q148R K14R, S17N, V31I, V32VG, S39R, V79I, L101I, S119G, T122I, T125A, P142SB
 BRSP222BRSP222 RAL Y143RL74M, T97A, E138DE10D, V31I, M50I, L101I, T112V, S119P, T122I, T124N, T125A, I135V, E157Q, I203M, I208L, T218S, I220L, D253VB
 BRSP17BRSP17 RAL G140A, Q148R E10D, V31I, M50I, V79I, L101I, K111T, S119T, T124Q, T125A, I135V, I203M, I208L, L234LV, V259VIB
 BRSP10BRSP10 RAL  T97A, V151IS17N, S24A, G59E, I60L, I72V, L101I, T112V, T124N, T125AB
 BRSP367BRSP367 RAL G140S, Q148H D6E, S17N, R20K, M22L, L28M, E35Q, S39N, L101I, T125A, K136N, I200L, V201IB
 BRSP148BRSP148 RAL G140S, Q148H S17N, A21S, D25E, V31I, L63LI, L74I, L101I, K111R, I113L, S119P, T122I, T125A, G163E, H171Q, T218S, S283GB
 BRSP263BRSP263 RAL   D6N, K7E, V31I, L74I, T112I, T125A, F181L, T206S, L234I, D288NB
 BRSP385BRSP385 RAL N155HV151IS24G, S119P, T122I, T124A, T125A, V201I, A205S, S255NB
 BRSP208BRSP208 RAL   E11D, V31I, K42KR, L101I, K111T, I113V, S119P, T125A, I135V, F181L, V201I, I204IV, T206S, E212A, T218S, K219T, N222K, N254NK, C280SB
 BRSP268BRSP268 RAL N155HV151IS17N, L28I, T112I, S119G, T122I, T124N, T125A, E157Q, K160Q, V201IB
 BRSP594BRSP594 RAL G140S, Q148H D6N, K7D, V32I, L45V, L101I, T125A, I135VB
 BRSP145BRSP145 RAL N155HV151VIS17N, S24D, L28I, S39C, T124N, T125A, V126L, T218S, D278NB
 BRSP591BRSP591 RAL  V151IS17N, L101I, S119P, T124N, T125A, I135V, S195C, D256EB
 BRSP296BRSP296 RAL E138K, G140C, Q148RV54IE11D, V31I, V32I, V37I, D41N, V79I, L101I, T125A, K136Q, V201I, T206S, L234V, D270EB
 BRSP195BRSP195 RAL   E10D, D41N, M50T, L101I, T122I, T124A, T125A, V201I, I208L, S283GB
 BRSP239BRSP239 RAL E138K, S147G, Q148RV151I, G163RK14R, L74I, V75M, V79I, S119P, T122I, T124A, T125A, K156N, V201I, T218I, L234V, D256E, S283G, R284GB
 BRSP322BRSP322 RAL   D6T, K7Q, E10D, R20K, G59GE, I72V, S119P, T122V, T125A, I203M, T206S, I208IL, L234LH, D278E, S283GB
 BRSP458BRSP458 RAL E138AT, G140S, Q148H D6NS, K7E, S17N, V31I, L101I, T124TN, T125A, K156N, K160KR, I203M, Q221K, N222K, D256E, R284GB
 BRSP39BRSP39 RAL G140S, Q148H A23V, T125A, M154I, A169T, R187K, K188R, V201IB
 BRSP521BRSP521 RAL G140S, Q148H V31I, L63I, G70E, L101I, S119R, T122I, T125A, K160R, V201I, A205S, L234IB
 BRSP551BRSP551 RAL   S17N, D41E, I72V, L101I, S119G, T122I, T125A, V201I, A205AV, T218L, K219Q, L234I, D256EB
 BRSP14BRSP14 RAL G140S, Q148H Y15I, H16N, I72V, V88I, L101I, T122I, T125A, I135V, F181L, V201I, L234V, K273Q, D278NB
 BRSP473BRSP473 RAL   V31I, V88I, L101I, T125A, K173KR, F181L, A265VB
Hurt (2014)IN_937IN_937 RAL G140S, Q148H K7Q, E11D, R20RK, V31I, I113V, T124N, T125A, G193E, T218I, S230N, D256E, D286NB
 IN_207IN_207 RAL G140S, Q148H L63I, G70N, L101I, T125A, F181L, V201I, I208L, T218S, S283GB
 IN_867IN_867 RAL N155H A23V, S24G, L28I, I72V, T112A, S119P, T124N, T125A, V165L, I182V, S230N, R231KB
 IN_883IN_883 RAL E92QT97A, V151IS17N, L28I, A49P, I72IV, K111R, S119T, T124A, T125A, V165VIB
 IN_321IN_321 RAL G140S, Q148HT97AE11D, V31I, I72IV, T112TI, S119P, T122I, T125A, V126VL, G163GV, V201I, N254Q, S255GB
 IN_3040IN_3040 RAL  T97TA, N155NDE11D, L28I, V37I, S39C, M50I, I72V, T112A, T124A, T125A, D167E, V201I, D253E, S283GB
 IN_2223IN_2223 RAL E138EK, G140S, Q148H K14R, S17C, M50I, I72V, T125A, I135V, M154I, R187RK, T206S, K219N, N222K, D286NB
 IN_954IN_954 RAL Y143RL74M, Q95K, T97AD6E, E10D, S17T, A23V, A91T, L101I, S119P, T122I, T124A, T125AB
 IN_2564IN_2564 RAL Y143CV151VI, G163RE11D, S24N, D25E, V31I, V75M, L101I, L104M, T125A, A205T, T218S, S230K, N254K, S255G, R284GB
 IN_1459IN_1459 RAL N155HT97AS17N, M50MV, L101I, K111R, T112I, S119R, T124G, T125A, V165I, E198D, V201I, I220L, Y227F, D256E, D278DNB
 IN_65IN_65 RAL E138K, S147G, Q148R K7R, K14R, K71N, V79VI, A91AT, S119R, T124N, T125A, K156N, G193E, V201I, N222K, S230N, L234VB
 IN_870IN_870 RAL G140S, Q148H H51HR, L101I, G106A, I113V, T124S, T125A, D167E, L234IB
 IN_668IN_668 RAL Y143CT97A, G163R, S230RS17N, T124A, T125A, K211Q, S283SGB
 IN_1894IN_1894 RAL N155HV151IS17N, D55DE, I72V, A98G, K111R, I113V, T124A, T125A, V126F, E170A, V201I, I220L, I251VB
 IN_1064IN_1064 RAL G140S, Q148H S17N, A21S, A23V, V31I, L45V, I72IV, L101I, T124A, T125A, V126A, V176L, T218SB
 IN_2852IN_2852 RAL G140S, Q148H D25E, P30A, L101I, T112A, T125A, V201I, S230N, R231K, S283GB
 IN_882IN_882 RAL N155H E11D, S17C, L101I, I113V, S119R, T125A, D256EB
 IN_1083IN_1083 RAL G140S, Q148H V31I, K111T, I113V, T125A, G189GR, G197GR, I203MB
 IN_2676IN_2676 RAL N155H D6E, E10D, R20K, V31I, M50I, L101I, I113V, S119P, T122TI, T124N, T125A, K156N, E157Q, V201I, A265VB
 IN_617IN_617 RAL G140S, Q148RL74IME11D, L28I, V37I, I72V, L101I, T112K, S119P, T122I, T124A, T125A, D167E, K211Q, Q216QR, L234V, A265VB
 IN_301IN_301 RAL N155H S17N, M50I, Y99YH, L101V, T124A, T125A, K156N, V165I, Y194C, V201I, T206S, N222K, S230N, S255T, I268L, K273Q, D278AB
 IN_920IN_920 RAL N155HV151IL45I, M50R, E69D, I72V, L74I, I84L, L101I, T112R, T125A, E157Q, K160Q, G163V, V201I, E212A, K215N, D256E, R284GB
 IN_118IN_118 RAL N155HL68LV, V151VIE11D, K34R, S119T, T125A, K156N, E157Q, V180VI, V201VI, I208IL, S230N, E287EAB
 IN_2999IN_2999 RAL Y143YCHRT97TAK7R, S17N, V31I, L74I, F100Y, L101I, K111T, S119T, T124TA, T125A, T206S, T218TS, D256EB
 IN_139IN_139 RAL  E92EKE11D, E13ED, W19W*, R20RK, S24SN, I60IV, G70GE, I113V, S119P, T122I, T124TS, T125A, I141V, L234IB
 IN_1416IN_1416 RAL E138AT, G140GS, Q148H S17N, I72IV, K111KN, T112TI, T124A, T125A, V126VF, I141IV, K156KN, G163Q, K211RB
 IN_212IN_212 RAL Y143RL74M, T97AS17N, R20K, V31I, T112S, I113V, S119ST, T124S, T125A, E157Q, K160Q, V201I, K211R, R284GB
 IN_880IN_880 RAL G140S, Y143H, Q148H S17N, K34R, T124R, T125A, V201I, S230NB
 IN_1642IN_1642 RAL Y143RL74M, T97AS17N, L101I, S119G, T122I, T124A, T125A, L234V, V259IB
 IN_2840IN_2840 RAL Y143R Y15YF, S17N, N18NH, L45I, M50I, L101I, K111KR, T112R, T124A, T125A, K156N, V201I, D256EB
 IN_2513IN_2513 RAL E138K, G140S, Q148H S17N, T124N, T125A, K127KR, M154I, V165IB
 IN_353IN_353 RAL N155HV151IS39C, M50I, T125A, V126M, E157Q, K160Q, G193E, I203M, I208IM, D232N, D286NB
 IN_81IN_81 RAL G140S, Q148RL74MS17SN, I72V, F100S, L101I, K111T, S119P, T124A, T125A, E157Q, K160KINB
 IN_1438IN_1438 RAL G140S, Q148H S17N, M50I, I72V, I113V, T124A, T125A, V201I, I220L, Y227F, R284GB
 IN_1750IN_1750 RAL G140S, Q148HL74IMVI72V, L101I, T125A, H171L, F181L, V201I, Q221QR, D256EB
 IN_1213IN_1213 RAL G140S, Q148H E11D, K14R, R20K, M50T, I113V, T124N, T125A, G193E, T206S, Q274QR, D288NB
 IN_216IN_216 RAL N155HV151I, G163RS17N, V31I, S39N, I84M, L101I, I113V, T124A, T125A, E157Q, K160T, I208IM, K211T, S230N, A265AV, R269RK, D270HB
 IN_866IN_866 RAL  S147SNI72V, T112R, S119P, T124N, T125A, S153SA, K188RT, I200M, V201I, I203M, I220L, Q221S, A265V, R284RGB
 IN_1016IN_1016 RAL G140GS, Q148H K14R, I84V, T112A, I113IV, T125A, K136KR, M154I, S230N, L234VB
 IN_2237IN_2237 RAL N155HV151IS17N, V31I, L101I, T124A, T125A, G163V, V201I, I220L, D232N, D256EB
 IN_1269IN_1269 RAL N155H D6DE, E10D, S17SN, I72IV, S119P, T122I, T124A, T125A, V201I, I208M, Y227F, S230N, D253Y, D256E, R284GB
 IN_1998IN_1998 RAL Y143YCHRT97TAV31I, I60IM, L74I, T112I, T124A, T125A, V126M, E157Q, K160Q, F181L, T206S, N254Q, S255SGB
 IN_2453IN_2453 RAL N155HV151IK7R, S17N, L28I, P30A, M50I, I72V, L101I, T112A, T124A, T125A, K136R, K156N, V201I, T218S, L234H, D256E, M275VB
 IN_1564IN_1564 RAL  L74M, T97A, Y143G, G163GRS17N, S39N, L101I, T112A, S119R, T124A, T125A, I135V, Y194L, S195H, A196T, K211KR, S230SN, I268L, D270H, R284RGB
 IN_1612IN_1612 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_1611IN_1611 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_914IN_914 RAL E138A, G140S, Q148H S17N, L45IT, L101I, T124A, T125A, V126VA, E157Q, K160Q, G163E, V165IB
 IN_1770IN_1770 RAL Y143R D25E, V31I, M50MI, L74I, K111KR, S119T, T125A, G163Q, V201VI, T218SB
 IN_3310IN_3310 RAL N155HE138D, V151IS17N, V31I, T124N, T125A, V126L, I135IV, K136KT, K156N, V201I, T206S, D232N, D256EB
 IN_1794IN_1794 RAL N155HV151VIS17N, I84L, L101I, K111T, T124A, T125A, E157Q, K160TB
 IN_3184IN_3184 RAL G140S, Q148H K7KR, S17N, S24N, L101I, T112I, T124N, T125A, T206S, S230N, D256E, A265AV, D286DNB
 IN_2547IN_2547 RAL N155HV151VIS17N, T124A, T125A, V126L, I135V, K156N, E157EQ, K188R, V201I, T206S, D232DN, D256E, R269K, D270H, R284GB
 IN_138IN_138 RAL  E92EKE11D, E13ED, R20RK, S24SN, I60IV, G70GE, I113V, S119P, T122I, T124TS, T125A, I141V, L234IB
 IN_1031IN_1031 RAL E138EK, G140S, Q148H K14KR, S17N, M50L, L101I, K111Q, I113V, T124A, T125A, I141IV, V150VAIT, M154MI, T218SB
 IN_984IN_984 RAL Y143R S17N, P30S, M50I, I72V, T124A, T125A, T206S, D253E, S255K, S283GB
 IN_761IN_761 RAL Y143YC E11D, E13ED, K14KR, S24N, V31I, V88VI, L101I, T124S, T125A, K136N, I204VB
 IN_623IN_623 RAL G140S, Q148H S17N, S119P, T122I, T124A, T125A, V201I, T206S, E212A, Q216H, T218S, K219N, D256EB
 IN_2946IN_2946 RAL G140S, Q148H E10D, G59E, S119P, T122V, T124A, T125A, T218SB
 IN_1795IN_1795 RAL Y143CT97A, G163GR, S230RS17N, R20RK, V31I, A80S, L101I, S119T, T124A, T125A, T206S, D256E, S283GB
 IN_1326IN_1326 RAL N155DH S17N, V31VI, V79VI, L101I, I113V, T124A, T125A, G163GEB
 IN_1569IN_1569 RAL  L68V, L74M, E92L, T97AK34R, M50I, V88VI, T112TA, T125A, V201I, T218S, S230NB
 IN_2339IN_2339 RAL G140S, Q148H L28I, V37I, S39C, T112A, S119P, T124N, T125A, I208IL, T210TI, K211KR, T218S, D232DNB
 IN_1789IN_1789 RAL Y143RT97A, G163RS24N, S119P, T125A, I135V, T206S, T210I, S283GB
 IN_2201IN_2201 RAL N155H K7R, A23V, L101I, T112I, S119P, T124N, T125A, I135VB
 IN_1302IN_1302 RAL G140S, Q148H T124A, T125A, K156N, R187K, V201I, S230N, A276APB
 IN_2021IN_2021 RAL Y143RT97AV31I, I60M, L74I, T112I, T124A, T125A, V126M, E157Q, K160Q, F181L, T206S, N254QB
 IN_1200IN_1200 RAL G140S, Q148R S17N, V31I, G106A, T125A, V126L, K156N, G163T, K173R, V201I, D253DN, D256EB
 IN_214IN_214 RAL Y143RL74M, Q95QK, T97AE10D, V31I, L101I, T112A, S119T, T124A, T125A, I135VB
 IN_1321IN_1321 RAL Y143RL74IM, T97AK14KR, S17N, T112A, S119T, T124A, T125A, A128PS, V201IB
 IN_2183IN_2183 RAL E92EQ, Y143YH, N155NHT97TAD6E, S17N, I113V, S119P, T124R, T125A, T206S, D207DEB
 IN_1431IN_1431 RAL E138EK, G140GA, Q148QK, N155NH D6E, S17N, I84IV, T124N, T125A, V126L, I135V, K188R, K211KN, T218S, I220L, V225C, Y227F, L234V, A265V, I268V, R269KB
 IN_539IN_539 RAL G140S, Q148HL74LMS24G, L45V, L101I, T112TAIV, I113IMV, T125AB
 IN_101IN_101 RAL G140S, Q148H S17N, V31I, L45V, L101I, I113V, T124A, T125A, G163E, F181L, V201IB
 IN_2457IN_2457 RAL G140S, Q148RG163KE11D, S24N, L101I, K111KR, T112A, T125A, K156NB
 IN_1641IN_1641 RAL G140S, Q148H E10D, E11D, A21T, M50I, I72V, I113L, S119P, T122I, T125A, L234I, D253E, D256EB
 IN_878IN_878 RAL Y143R S17N, V31I, I113V, T124N, T125A, V126M, T206S, D256E, A265VB
 IN_1757IN_1757 RAL F121Y S24N, L101I, T112A, S119P, T124TN, T125A, M154L, Q177L, D232NSB
 IN_1656IN_1656 RAL Y143RT97A, G163RE11D, S24N, D25E, V31I, L101I, K111R, T112A, S119P, T122I, T125A, R187K, I220L, K240KRB
 IN_3244IN_3244 RAL N155H D6DE, S17N, D25E, K34R, M50MI, L101LI, T124N, T125A, I135V, M154I, V201VI, K219N, N222K, D286DNB
 IN_2012IN_2012 RAL Y143RT97A, G163EKK7Q, E10A, E11D, K14R, V31I, L45V, L101I, T125A, E170EQ, G193R, V201I, I208M, E212A, Q216H, K219Q, S230N, D256EB
 IN_134IN_134 RAL G140S, Q148H D6E, E10D, E13D, I72V, T124G, T125A, V126L, L234LVB
 IN_1013IN_1013 RAL G140S, Q148H S17N, I72V, L101I, T124N, T125A, D167E, K173R, A179S, G193D, S195C, I220L, Y227F, S255N, D256E, D278N, S283GB
 IN_758IN_758 RAL Y143RT97AV31I, L74I, T112I, T124A, T125A, V126M, E157Q, K160Q, F181L, T206S, N254Q, S255SG, V259VI, S283SGB
 IN_995IN_995 RAL G140C, Q148RL74M, E138GS17N, L101I, T124A, T125A, D167E, D253EB
 IN_2074IN_2074 RAL Y143YCHR, N155NH D25DE, K34KE, M50MV, T112I, S119SG, T122I, T124N, T125A, V201I, T218S, K219KRB
 IN_133IN_133 RAL G140S, Q148H E11D, R20K, D25E, V31I, V32I, D41N, K111T, T125A, V126M, I135V, V201I, T218SB
 IN_1928IN_1928 RAL G140S, Q148H V31I, G70GR, K111T, T112TI, S119G, T122I, T125A, V201I, K211R, L242I, D256EB
 IN_202IN_202 RAL E138EK, G140GS, Q148QH K14R, R20RK, V31I, I113V, T124A, T125A, G193E, V201I, A205S, T206S, T218S, R231K, N254KB
 IN_1121IN_1121 RAL E138K, G140S, Q148RG163GRE11ED, K14KR, S39SN, L45LI, T112A, T124A, T125A, K136E, K156N, G193R, T206S, I208L, K211KQ, E212A, T218S, D232DN, L234I, A265AVB
 IN_2785IN_2785 RAL E92QT97A, V151IE11D, K14R, S24N, D41DN, L63I, L74I, L101I, T112S, T125A, G163E, V201I, I208M, L234V, D279GB
 IN_861IN_861 RAL G140S, Q148H K7Q, S17N, V31I, I72V, S119P, T122I, T124A, T125A, V126L, V165I, V201I, Q216H, D256E, A265VB
 IN_2139IN_2139 RAL N155NH D6N, K7E, K14R, S17N, V31I, S39R, P90PS, T112V, S119SR, T124A, T125A, I135V, S230N, N254Q, S255GB
 IN_2885IN_2885 RAL N155HV151I, G163EKE10ED, L101V, T124N, T125A, I135V, H171HR, V201I, L234I, D256EB
 IN_341IN_341 RAL E92QL68V, L74M, T97AE10D, V31I, M50I, I73V, E96D, L101I, S119T, T124N, T125A, I135V, E157Q, K160T, I208M, S230N, D232E, L234F, D253E, D256E, E287EAB
 IN_1418IN_1418 RAL G140S, Q148HV151IE10D, V31VIM, M50T, I72V, I113V, T124A, T125A, Q216NB
 IN_1952IN_1952 RAL G140GS, Q148QHKNG163GRS17N, V31VI, I72V, L74I, I89IL, I113IL, T124A, T125A, K156N, D167E, V201I, I220L, Y227F, S230N, D256EB
 IN_1276IN_1276 RAL E92EQ S17N, K111R, T112M, T124A, T125A, G163Q, K264KR, D270DEB
 IN_1632IN_1632 RAL G140S, Q148H E10D, E11D, A21T, M50I, I72V, I113L, S119P, T122I, T125A, L234I, D253E, D256EB
 IN_746IN_746 RAL E138K, Q148R E13ED, L45AV, K111R, T112TI, T124A, T125A, V126L, K211R, S230N, R284RGB
 IN_2250IN_2250 RAL Y143CT97A, S230RS17N, C56CR, I72V, F100Y, L101I, K111T, I113L, T124R, T125A, I203M, T206S, I208L, E212L, T218SB
 IN_2674IN_2674 RAL N155HQ95K, T97TA, V151VIS17N, L101I, S119P, T124A, T125A, I135V, K136QB
 IN_373IN_373 RAL G140S, Q148H I72V, L101I, S119P, T125A, V126A, G193D, V201I, I268L, D270HB
 IN_913IN_913 RAL N155H S17N, L28I, S39C, I72V, I113V, T124N, T125A, A133AT, V180I, F181L, V201I, T206S, K219N, N222K, I268L, D270HB
 IN_1868IN_1868 RAL G140S, Q148HE138DS17N, V31I, I72V, I113V, T124A, T125A, T206SB
 IN_1144IN_1144 RAL G140S, Q148H S17N, L28I, I72V, T112TI, I113IV, T124A, T125A, V126M, I141V, R284GB
 IN_1128IN_1128 RAL E92EQ S39SN, M50MI, T125A, I135V, M154I, I162V, V201I, K215N, L234IB
 IN_3034IN_3034 RAL N155HV151IS17N, V31I, I72V, L74I, L101I, I113V, T124S, T125A, I135IV, K156N, H171Q, F181L, V201I, T206S, Q221R, D232DN, A265V, R284IB
 IN_755IN_755 RAL G140S, Q148H S17N, M50I, I72IV, I84IV, L101I, K111T, T124A, T125A, K156N, D167E, G193R, V201I, T206S, Q216N, S230N, D232DNB
 IN_787IN_787 RAL E92QL68V, L74M, T97AE10D, V31I, M50I, I73V, E96D, L101I, S119T, T124N, T125A, I135V, E157Q, K160KPQT, I208M, S230N, D232E, L234F, D253E, D256EB
 IN_487IN_487 RAL Y143RL74M, Q95QK, T97AE10D, V31I, L63LI, L101I, T112A, S119T, T124A, T125A, I135VB
 IN_1097IN_1097 RAL E138EA, G140S, Q148H S17N, E87D, T112A, T124N, T125A, M154I, V201VIB
 IN_3296IN_3296 RAL E92EQT97TA, V151VIE11D, K14R, S24N, L63LI, L74I, L101I, T112TS, T125A, I135IV, G163E, R166RK, V201I, T210TI, L234V, D279G, D286DNB
 IN_992IN_992 RAL G140S, Q148H S17N, L101I, S119G, T122I, T124A, T125A, K211Q, D256E, D278DNB
 IN_2253IN_2253 RAL E138K, G140A, Q148K E11D, A21T, V31I, L45V, L101I, K111T, I113V, T125A, G163T, I203M, T218S, K219KT, D253E, D256E, D279GB
 IN_782IN_782 RAL G140S, Q148H E11D, E13D, R20K, D25E, V31I, M50MI, T112A, T124A, T125A, V201I, A205S, I208M, K215N, R231K, N254K, S255G, K258RB
 IN_1634IN_1634 RAL G140S, Q148H E10D, E11D, A21T, M50I, I72V, I113L, S119P, T122I, T125A, L234I, D253E, D256EB
 IN_1619IN_1619 RAL E138A, G140S, Q148HL68LVM50I, I72IV, I113V, T124N, T125A, M154L, D167E, V201IB
 IN_3281IN_3281 RAL G140S, Q148H E10D, V32I, L45V, L101I, T125A, K159KE, G163E, Y227F, D253H, D256EB
 IN_879IN_879 RAL E92EQ, N155HV151VIE11D, K14R, V32I, S39C, M50I, L101I, I113V, T125A, I135V, S195T, V201I, D232DNB
 IN_2519IN_2519 RAL Y143HL74M, T97A, G163RE11D, K14R, A21T, S24G, D25E, S39C, L45V, L101I, S119G, T122I, T125A, E170EG, T206TS, Q216H, S283SNB
 IN_1233IN_1233 RAL N155HG163GRS17N, V31VI, T124A, T125A, K136KT, K156N, V165I, G193R, V201IB
 IN_553IN_553 RAL G140S, Q148H S17N, M50ML, E87D, T112TA, T124N, T125A, M154I, V201VIB
 IN_1332IN_1332 RAL E92EQ, N155HQ95QKD6E, E10D, V31VI, L101I, T112I, T124N, T125A, I135V, I182V, V201I, T206S, I268L, D270DNB
 IN_2443IN_2443 RAL N155NH L45Q, V77I, I84M, L101I, T125A, D167E, V201IB
 IN_2368IN_2368 RAL Y143YC E10D, V31I, T112AS, I113V, S119SR, T124N, T125AB
 IN_1243IN_1243 RAL E138EA, S147SG, Q148QR, N155NH K7R, S17N, L101I, S119SR, T124S, T125A, K156N, G193E, T218I, L234I, D256E, D286NB
 IN_1191IN_1191 RAL Y143YCQ95QK, T97TAV31I, K34R, L101I, T112A, T124S, T125A, I135V, K156KR, D207E, E287EDB
 IN_942IN_942 RAL N155NHE138D, V151VIK7R, S17SN, L28I, S39C, M50I, T112M, T124N, T125A, V165I, V201I, Q216R, K219NB
 IN_352IN_352 RAL E138K, G140S, Q148H E11D, K14R, V32I, S39C, V88I, L101I, K103R, S119G, T122I, T125A, I200M, V201I, T206SB
 IN_332IN_332 RAL Y143RT97A, E138DE11D, S17C, L101I, K111KR, T112K, S119G, T122I, T124TN, T125A, T218SB
 IN_293IN_293 RAL N155HV151I, G163RL45V, M50T, T124A, T125A, K156N, V165I, I182V, V201I, E212A, S283GB
 IN_315IN_315 RAL T66AL74M, V151VI, G163RV31I, V75VI, L101V, T112V, T125A, V126L, V165I, V201I, K211R, K215N, D229DN, S230N, D256E, S283GB