<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation T97A
Rx II-naive
IncludeMixtures No
References 12
Patients 15
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Dowling (2002)NKU3005NKU3005AF457089None  T97AK14R, A21T, V31I, I72V, T112V, I113V, T124A, T125A, V126F, G134N, I135V, D167E, V201I, K211R, N222K, L234V, I268L, S283GA
 KSM4024KSM4024AF457077None  T97AK14R, A21T, V31I, D41N, L74I, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, E157Q, K160Q, D167E, V201I, Q216H, Y227F, L234V, S283GA
Swanson (2003)UG95_422UG95_422AY214055None  T97AI60M, I72V, T112V, I113V, T124A, T125A, V126F, G134S, K136Q, D167E, V201I, S283GA
Fang (2004)ML752_3_1997752_3_1997AY322193None  T97AK14R, A21T, V31I, I60M, I72V, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, D167E, V201I, Q216H, L234IA
 ML605_3_1997605_3_1997AY322190None  T97AK14R, A21T, V31I, I72V, T112V, I113V, T124A, T125A, V126F, G134S, K136Q, F139Y, D167E, V201I, L234I, S283GA
Kijak (2004)1404MV01CM.1404AY371164None  T97AM50I, I84L, T112V, I113V, T124A, T125A, V126F, K136Q, D167E, V201I, L234I, S255N, A265V, D279N, S283GA
Meloni (2004)DDI579DDI579AY521629None  T97AK14R, A21T, V31I, I72V, L74I, T112V, T124A, T125A, V126M, G134N, D167E, V201I, L234I, V260I, S283GA
Njai (2006)MP141199CM.1411AM279396None  T97AV31I, L63M, I72V, L74I, T112V, I113L, T124N, T125A, V126M, G134N, K136Q, L158LF, D167E, V201I, I203M, T218S, L234IA
Vidal (2006)NV_KTB03502.KTB035AM000055None  T97A, A128TK7E, E10A, S17N, V31I, I72V, I84M, L101I, T112V, T125A, I135V, K136Q, V201I, I217V, T218L, L234I, D256E, D279G, S283GA
 KTB1397.KTB13AM000054None  T97AK14R, A21T, I72V, L101I, T112V, T124A, T125A, G134N, K136Q, L234I, S283GA
Brennan (2008)18-3018-30EU618108None  T97AE11D, A21T, A23V, V31I, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, T218S, Y227F, L234V, V260I, S283GA
Eshleman (2009)194.793194.793FJ480232None  T97AK14R, V31I, I72V, T112V, I113V, T124A, T125A, V126F, G134N, I135V, K136Q, D167E, V201I, K211R, L234I, S283GA
Garrido (2009)417INT-417GU217264None  T97AK14R, V31I, I60M, I72V, L101I, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, V201I, S283GA
Carr (2010)1402MV01CM.1402MVGU201505None  T97AM50I, I84L, T112V, I113V, T124A, T125A, V126F, K136Q, D167E, V201I, L234I, S255N, A265V, D279N, S283GA
Jahanbakhsh (2012)SYZ37SYZ37INTAB716176None  T97AD6E, K14R, N27NI, V31I, S39N, I60M, I72V, L74V, T112I, I113V, T124A, T125A, V126F, G134S, K136Q, D167EK, V201I, S283GA