<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation Q95S
Rx II-naive
IncludeMixtures No
References 4
Patients 4
Isolates 4
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Brennan (2008)ABB83-96ABB83-96EU618568None   E11D, V31I, M50I, I72V, P90T, Q95S, L101I, T112V, T124G, T125A, G134N, K136Q, D167E, V201I, Q216H, L234V, S283GA
Eshleman (2009)ABB102-97ABB102-97FJ480299None   K7R, K14R, V31I, M50I, Q95S, L101I, T112M, T124AG, T125A, K136Q, D167E, V201I, R224Q, L234I, W243XA
Hora (2015)DEURF10UG005DEURF10UG005KF716487None   S17N, I72V, Q95S, L101I, K111T, T112I, T124A, T125A, G134N, K136Q, V201I, A205S, L234I, S283GA
Billings (2016)KE530245V4KE530245V4KT022404None   E11D, K14R, A21T, V31I, Q95S, L101I, T112V, I113V, T124A, T125A, G134N, K136Q, V201I, I208L, Q216H, T218S, D256E, S283GA