<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation L74V
Rx II-naive
IncludeMixtures No
References 6
Patients 6
Isolates 6
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Neilson (1999)Q23-17Q23-17AF004885None   K14R, A21T, V31I, I72V, L74V, T112I, I113V, T124A, T125A, G134N, K136Q, D167E, V201I, Q216H, L242F, S283GA
Dowling (2002)MSA4071MSA4071AF457082None   K14R, V31I, M50I, I60M, I72V, L74V, E96D, K111Q, T112V, I113V, T124A, T125A, V126F, K136Q, V201I, K211R, T218S, Y227F, L234I, S255N, D278N, S283GA
Jahanbakhsh (2012)SYZ37SYZ37INTAB716176None  T97AD6E, K14R, N27NI, V31I, S39N, I60M, I72V, L74V, T112I, I113V, T124A, T125A, V126F, G134S, K136Q, D167EK, V201I, S283GA
Oliveira (2012)GD01GD01JQ670837None   K14R, V31I, I60LM, I72V, L74V, T112V, I113V, T124A, T125A, V126F, I135IV, K136Q, D167E, V201I, L234IA
Billings (2016)KE809842V2KE809842V2KT022368None   K14R, V31I, I72V, L74V, T112V, T124N, T125A, K136Q, D167E, V201I, T218I, S255N, I268LA
Billings (2016)CO6095V1CO6095V1KX907397None   A21T, M50R, I72V, L74V, T112V, I113V, T124A, T125A, V201I, S283GA