<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation L74M
Rx II-naive
IncludeMixtures No
References 4
Patients 10
Isolates 10
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Carr (2005)02UZ65202UZ652AY829203None  H51Y, L74MD3E, R20K, V31I, E48K, I72V, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 02UZ69402UZ694AY829205None  L74MD3E, R20K, V31I, E48K, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 02UZ69802UZ698AY829206None  L74MD3E, E11D, R20K, V31I, E48K, I72V, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 02UZ74002UZ740AY829208None  L74MD3E, R20K, V31I, I72V, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, I161T, D167E, V201I, T218I, L234I, S255NA
 02UZ065902UZ0659AY829209None  L74MD3E, R20K, V31I, I72V, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, D286EA
 02UZ066702UZ0667AY829211None  L74MD3E, R20K, V31I, I72V, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
Rodriguez (2006)1579A1579ADQ083238None  L74MV31I, M50I, I72V, P90Q, L101I, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, I203M, K219R, S283GA
Brennan (2008)54-754-7EU618238None  L74MS17SN, V32I, S39C, I72V, I84L, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, Y227F, L234I, S255K, S283GA
 A1806A1806EU618467None  L74MK14R, V32I, S39C, I72V, I84L, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, Y227F, L234I, S255K, S283GA
Jahanbakhsh (2012)SYZ40SYZ40INTAB716178None  L74MD6E, K14R, S17N, N27NI, V31I, E35Q, S39N, I60M, I72V, T112I, I113V, T124A, T125A, V126F, G134S, K136Q, D167E, V201I, I203M, S283GA