<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation L74I
Rx II-naive
IncludeMixtures No
References 39
Patients 175
Isolates 176
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Alizon (1986)MALCGMALMALCGX04415None   V31I, L74I, L101I, T112V, I113V, T124A, T125A, G134N, D167E, V201I, I203M, S230N, L234I, S283G, R284GA
Dowling (2002)KSM4024KSM4024AF457077None  T97AK14R, A21T, V31I, D41N, L74I, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, E157Q, K160Q, D167E, V201I, Q216H, Y227F, L234V, S283GA
Masharsky (2003)A011698UA0116AF413987None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
Meloni (2004)DDI579DDI579AY521629None  T97AK14R, A21T, V31I, I72V, L74I, T112V, T124A, T125A, V126M, G134N, D167E, V201I, L234I, V260I, S283GA
 DDJ360DDJ360AY521630None   K14R, A21T, V31I, I72V, L74I, T112V, T124A, T125A, V126M, G134D, D167E, V201I, L234I, V260I, S283GA
 DDJ369DDJ369AY521631None   K14R, A21T, V31I, M50K, I72V, L74I, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, K211Q, T218I, L234I, S283GA
 DDJ362DDJ362AY521632None   S24N, V31I, V32I, I72V, L74I, T112V, T124A, T125A, G134N, I135V, K136T, V165I, D167E, V201I, T206S, L234I, D279G, S283GA
Adojaan (2005)EST2002_3942002_394DQ167216None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, D232NA
Carr (2005)02UZ066302UZ0663AY829210None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
Njai (2006)MP102098CM.1020AM279379None   M50R, L63I, L74I, L101I, T112V, S119A, T124A, T125A, G134S, K136N, D167E, V201I, T206S, I208L, T218I, L234VA
 MP101498CM.1014AM279381None   K14R, A21T, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, K215N, T218I, L234IA
 MP141199CM.1411AM279396None  T97AV31I, L63M, I72V, L74I, T112V, I113L, T124N, T125A, V126M, G134N, K136Q, L158LF, D167E, V201I, I203M, T218S, L234IA
Saad (2006)01UADN12101UADN121DQ823358None   V32I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 01UADN13901UADN139DQ823357None   D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255N, S283GA
 01UAKV25401UAKV254DQ823361None   D3E, R20K, V31I, I72V, L74I, L101LV, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 01UAPol29301UAPol293DQ823359None   D3E, E11D, R20K, A21T, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, K211R, T218I, L234I, P238S, S255NA
 01UAPol29401UAPol294DQ823356None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 01UAPol30301UAPol303DQ823360None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, W243X, S255NA
 01UAOD1001UAOD10DQ823365None   D3E, K14R, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 01UAOD3501UAOD35DQ823366None   D3E, K7Q, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255NA
 01UAOD8901UAOD89DQ823367None   D3E, R20K, L28I, L45Q, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255NA
Tatsumi (2006)GHNJ176GHNJ176AB231894None   K14R, V31I, M50I, I72V, L74I, T112V, I113V, T124A, T125A, V126M, G134D, K136Q, G163E, V165I, V201I, T206P, N222H, L234I, S283G, D288NA
 GHNJ193GHNJ193AB231897None   K14R, W19G, V31I, M50T, I72V, L74I, T112V, I113V, T124A, T125A, V126M, G134D, K136Q, G163E, V165I, V201I, E212A, N222H, L234I, S283G, D288NA
Zarandia (2006)03GEMZ03703GEMZ037DQ207944None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
Badreddine (2007)J11469SB_J11469DQ375282None   E11D, K14R, A21AT, A23V, V31I, V32I, S39N, D41N, M50I, I72V, L74I, L101I, T112V, T125A, G134D, K136Q, D167E, V201I, K211KR, Q216H, N222H, L234I, D279G, S283GA
Eyzaguirre (2007)KZYUZ30041302Y300413EF589040None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, G163E, D167E, V201I, T218I, L234I, S255NA
 KZYUZ30042502Y300425EF589041None   D3E, D6N, R20K, V31I, E35K, M50T, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 KZKAR30043502K300435EF589042None   D3E, R20K, V31I, H51P, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 KZPAV30048002P300480EF589043None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, K160R, D167E, V201I, T218I, L234I, S255NA
 KZPAV30049702P300497EF589039None  V54ID3E, S17N, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 KZPAV30050202P300502EF589044None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
Brennan (2008)124-33124-33EU618078None   K14R, A21T, S39C, L63I, I72V, L74I, T112V, I113V, S119ST, T124A, T125A, V126M, G134N, I135V, D167E, V201I, K211R, Q216H, L234I, S283GA
 193-6193-6EU618116None   E11D, E13ED, K14KR, A21T, V31I, L63I, I72V, L74I, T112V, T124A, T125A, V126M, G134DN, I135V, D167E, V201I, Q216H, L234I, A265AV, S283GA
 239-40239-40EU618123None   E11D, K14R, A21T, M22MI, A23V, V31I, V32I, D41N, M50I, I72V, L74I, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, L234I, S283G, D288NA
 393-17393-17EU618170None   V31I, M50I, L63I, I72V, L74I, F100Y, T112I, T124A, T125A, K136Q, D167E, V201I, L234I, S255NA
 476-16476-16EU618204None   K14R, A21T, V31I, I72V, L74I, T112I, T124G, T125A, G134N, K136T, D167E, V201I, L234I, S283GA
 4832-94832-9EU618207None   E11D, V31I, V32I, L45I, I72IV, L74I, I89IV, T112V, T124TA, T125A, V126M, G134D, G163E, G193GE, V201I, L234I, N254KA
 ABB08-96ABB08-96EU618497None   K14R, A21T, V31I, L63V, I72V, L74I, T112V, S119G, T122I, T124A, T125A, K136Q, D167E, Q216H, L234I, A265V, S283GA
 ABB191-98ABB191-98EU618617None   K14R, A21T, A23V, D41N, L63I, I72V, L74I, T112V, T124A, T125A, V126M, G134D, I135V, D167E, V201I, Q216H, L234I, S255G, R269K, S283GA
Van Laethem (2008)AR02-766AR02-766EU882783None   K14R, V31I, V32VI, M50MI, I72V, L74I, T112V, I113IV, T124A, T125A, K136Q, D167E, V201I, K211KR, T218TI, L234IV, S283GA
Brumme (2009)INT_3927INT_3927FJ813378None   K14R, S17C, I72V, L74I, T112IV, T124A, T125A, G134N, K136Q, D167E, V201I, L234I, S283GA
Eshleman (2009)ABB08-96ABB08-96FJ480267None   K14R, A21T, V31I, L63V, I72V, L74I, T112V, S119G, T122I, T124A, T125A, K136Q, D167E, Q216H, L234I, A265V, S283GA
 ABB213ABB213FJ480319None   E11D, K14R, A21T, V31I, M50MV, I72V, L74I, T112V, T124A, T125A, V126M, G134N, K136Q, D167E, V201I, I208M, L234I, S283GA
Garrido (2009)15INT-15GU216862None   K7E, E11D, S24N, I72V, L74I, T112I, T124A, T125A, V126M, K136Q, M154ML, V201I, T206S, Q209R, L234I, S255N, D256EA
 59INT-59GU216906None   E11ED, R20RK, F26FS, V31I, D41N, I72V, L74I, P90S, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, I251ICFS, S255NA
 107INT-107GU216954None   R20K, V31I, L45Q, I72V, L74I, T112V, I113V, S119P, T124G, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 157INT-157GU217004None   E11D, R20K, V31I, I72V, L74I, T112V, I113V, H114T, T115AG, D116LQ, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, K215N, T218I, L234I, S255NA
 368INT-368GU217215None   K14R, A21T, I60M, I72V, L74I, T124A, T125A, K136KQ, D167E, H171Y, R187RG, L234I, S283GA
 411INT-411GU217258None   K14R, I72V, L74I, T112V, S119A, T124A, T125A, G134D, K136Q, D167E, K173R, V201I, E212I, T218I, L234I, S283GA
Niama (2009)97CD.MBFE185CD.MBFE185FN392874None   V31I, L74I, T112V, S119P, T124A, T125A, G134N, K136Q, D167E, V201I, L234I, L241LP, S283GA
 97CM.MP814CM.MP814FN392876None   K14R, V31I, S39C, M50I, L74I, T112V, T124A, T125A, G134D, D167E, V201I, K211R, L234I, V260VL, V281VM, S283GA
Sichtig (2009)44374437FJ183485None   K14R, V31I, L74I, L101I, T112V, I113V, T124A, T125A, I135IV, K136Q, G163A, G193E, V201I, L234IA
 44434443FJ183486None   E11D, V31I, V32I, V37I, D41N, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, K211KR, T218I, L234I, S255N, A276AGA
 16-E16-EFJ183491None   D3DE, K7KQ, R20K, V31I, I72V, L74I, T112V, I113IV, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 20-E20-EFJ183543None   D3E, E11D, R20K, V31I, I72V, L74I, K111N, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255NA
 54-E54-EFJ183555None   V31I, I60IL, I72V, L74I, T112V, I113V, T124A, T125S, V126M, G134N, K136Q, K173KR, I182V, V201I, T206S, I208L, L234IA
 48764876FJ183641None   D3E, Q9QE, E11D, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136H, D167E, V201I, K215N, T218I, L234I, S255NA
Avi (2010)N69N69GQ926814None   R20K, V31I, I72V, L74I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, S255NA
 N103N103GQ926848None   D3E, K14R, R20K, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, K136T, D167E, G193E, V201I, T218I, L234I, S255N, S283GA
Carr (2010)4038STN01CM.4038STNGU201508None   E11D, E13D, A21T, V31I, I72V, L74I, I84M, P90S, T112V, T124A, K136Q, D167E, V201I, K219N, N222K, L234I, S283GA
Gafarova (2010)31913191FJ465126None   K14R, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, H171Y, V201I, T218I, L234I, S255NA
Tovanabutra (2010)KECst_006KECst_006FJ623475None   K14R, V31I, V32I, I72T, L74I, T112V, I113V, S119P, T124S, T125A, K136Q, D167E, V201I, I203M, K219N, N222K, S283GA
 KECst_004KECst_004FJ623489None   K14R, S24N, V31I, I72V, L74I, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, S283GA
Brenner (2011)90229022HQ207785None   K14R, S24N, V31I, I72V, L74I, T112IV, I113V, T124A, T125A, G134D, K136Q, D167E, V201I, I208IM, E212EA, K219N, N222K, L234I, S283GA
 96119611HQ207798None   K14R, S24N, V31I, M50IT, I72V, L74I, T112V, I113V, T124A, T125A, G134D, K136Q, D167E, V201I, E212A, K219N, N222K, L234I, S283GA
Kousiappa (2011)CY207CY207JF683759None   E11D, R20K, V31I, I60M, I72V, L74I, T112V, I113V, S119T, T124A, T125A, V126F, G134S, K136Q, V201I, L234I, S283GA
 CY213CY213JF683763None   D3E, E11D, R20K, V31I, D64Y, I72V, L74I, E85Q, K111I, T112V, I113V, S119P, T124S, T125A, V126I, G134D, K136Q, D167K, H183L, V201I, L234I, S255NA
 CY231CY231JF683780None   D3E, E11D, R20K, A21T, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255N, S283NA
 CY255CY255JF683798None   V31I, I72V, L74I, I89L, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, M154I, D167E, V201I, L234I, S255NA
Fernandez-Garcia (2012)Irkutsk_5Irkutsk_5JQ292891None   R20K, V32I, D41N, Q44H, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, K156R, D167E, V201I, T218I, L234I, S255NA
 RU01029RU01029JQ292892None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 RUA001RUA001JQ292893None   D3E, R20K, V31I, L63V, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, V281MA
 RUA007RUA007JQ292894None   R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, D270EA
 RU_560_1125RU_560_1125JQ292895None   D3E, R20K, D41N, I72V, L74I, T112V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 RU_915_1016RU_915_1016JQ292896None   D3E, E11D, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, W132G, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 RU_915_1035RU_915_1035JQ292897None   D3E, K7KQ, R20K, I72V, L74I, S81SR, T112V, I113V, S119P, T124S, T125A, W132WG, G134N, K136H, D167E, V201I, T218I, L234I, S255NA
 RU_915_1038RU_915_1038JQ292898None   D3E, R20K, V31I, L74I, T112V, S119P, T124N, T125A, G134N, K136Q, E157EG, D167E, V201I, L234I, S255NA
 RU_915_1041RU_915_1041JQ292899None   V32I, I72V, L74I, K111R, T112V, I113V, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, V259IA
 RU_SP_B_049RU_SP_B_049JQ292900None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255NA
Jahanbakhsh (2012)THR02THR02INTAB716143None   K14R, E35Q, S39N, I60M, I72V, L74I, G106GA, K111R, T112V, I113V, T124A, T125A, V126F, G134S, K136Q, I141IF, D167EK, I191IM, S195T, V201I, I203M, S283G, R284RGA
Zhao (2012)LB045LB045JN864053None  T97AE11D, A21T, V31I, D41N, M50I, L63I, I72R, L74I, L101I, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, L234I, D279G, S283GA
Reigadas (2013)317317JX425438None   K14R, A21T, S39C, M50R, I72V, L74I, G106A, T112V, S119T, T124A, T125A, V126M, G134N, K136Q, V165I, G193E, V201I, T206S, T210I, T218S, Q221E, L234I, S283GA
 319319JX425440None   S24N, V31I, L63I, I72V, L74I, K111KQ, T112MV, T124A, T125A, G134N, K136T, D167E, V201I, T206S, E212A, L234I, D256E, S283GA
 344344JX425465None   E11D, K14R, A21T, V31I, D41N, S57R, I72V, L74I, A91T, T112V, T124A, T125A, G134N, K136Q, I182V, V201I, L234I, S283GA
 453453JX425786None   V31I, M50I, K71Q, I72V, L74I, T112V, T124A, T125A, V126M, G134D, I135V, K136Q, D167E, V201I, A205S, T218S, L234I, V260I, S283GA
 454454JX425787None   K14R, A21T, V31I, I72V, L74I, T112V, I113V, T124A, T125A, V126M, G134N, K136Q, D167E, V201I, L234I, S283GA
 605605JX425850None   K14R, V31I, M50I, I72V, L74I, T112V, I113IV, S119P, T122TI, T124A, T125A, V126M, G134DN, K136KQ, I161IT, G163GW, Q164QKLM, V165VL, D167EK, V201I, L234I, D256EA
 607607JX425852None   K14R, V31I, L45Q, I72V, L74I, E96D, T112V, T124A, T125A, V126M, G134N, I135V, K136Q, V201I, T206S, E212HQ, L234I, D256E, S283G, D286EA
 608608JX425853None   K14R, S39C, L63V, I72V, L74I, E96D, T112I, T124A, K136Q, V201I, L234I, S283GA
 612612JX425856None   K14R, V31I, M50I, L63I, L74I, T112I, T124A, T125A, V126M, K136Q, G163E, S195C, V201I, E212A, I217V, T218S, L234I, D279GA
 101099101099JX451927None   K14R, A21T, I72V, L74I, T112V, T124A, T125A, G134S, K136Q, D167E, V201I, D229DG, L234I, S283GA
Hora (2015)DEMA108RU003DEMA108RU003KF716491None   R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 DEURF10KE001DEURF10KE001KF716469None   K14R, V31I, I72V, L74I, L101M, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, S255SN, S283GA
Moskaleychik (2015)MSK_SK_006MSK_SK_006KY238327None  L68LIR20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 MSK_SK_007MSK_SK_007KY238328None   R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, D270EA
Tongo (2015)BS13BS13KR017772None   K14R, A21T, E69G, I72V, L74I, T112V, T124A, T125A, V126M, G134N, I135V, K136T, D167E, V201I, T206S, I208L, Q221T, L234I, S255N, A265V, S283G, R284G, D286AA
Wilkinson (2015)TV096TV096KJ948658None   K7R, E11D, K14R, A21T, M50I, L74I, I84M, G106A, T112V, T124A, T125A, G134DN, K136Q, D167E, V201I, L234I, K240R, D256E, S283GA
Billings (2016)KE851891V4KE851891V4KT022376None   K14R, A21T, V31I, S39N, I72V, L74I, T112V, I113V, T124A, T125A, G134N, K136Q, I141V, D167E, K188R, V201I, Q216N, L234V, V260I, I268L, R269K, D270N, S283G, D286NA
 KE795643V7KE795643V7KT022384None   K14R, A21T, V31I, S39N, D41N, I72V, L74I, T112V, I113V, T124A, T125A, G134N, K136Q, I141V, D167E, V201I, Q216N, L234V, V260I, I268L, R269K, D270N, S283G, D286NA
 KE888800V3KE888800V3KT022397None   S17N, D41N, I72V, L74I, T112V, I113V, T124A, T125A, G134D, K136Q, M154L, D167E, K173R, V201I, L234V, D256EA
 KE484390V7KE484390V7KT022414None   L63V, I72V, L74I, A91E, T112V, I113V, S119R, V201I, T218I, L234I, D256E, A265V, S283GA
Gashnikova (2016)51IN_51KX574451None   D3E, R20K, V31I, I72A, L74I, T112V, I113V, S119P, T124S, T125A, C130F, G134D, K136Q, D167E, V201I, L234I, S255NA
 7IN_7KX574447None   D3E, E11D, R20K, V31I, I72V, L74I, T112K, I113V, S119P, T124S, T125A, G134N, K136Q, G163E, D167E, G193E, V201I, Q216R, L234I, S255NA
 43IN_43KX574450None   D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 3IN_3KX574441None   E11D, E13D, K14R, S24N, V32I, I72V, L74I, T112V, I113V, S119P, T124G, T125A, G134N, K136Q, V201I, N222K, L234I, S255N, I268VA
 31IN_31KX574443None   D3E, S17C, R20K, V31I, D55N, L63V, I72V, L74I, T112A, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255NA
 58IN_58KX574452None   D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, G193E, V201I, T218I, L234I, S255NA
 5IN_5KX574446None   D3E, E11D, R20K, V31VI, V32VI, L63LV, I72IV, L74I, T112I, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T206S, L234I, S255NA
 40IN_40KX574449None   D3E, E11D, R20K, V31I, I72V, L74I, T112I, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, K215N, L234I, S255NA
 14IN_14KX574448None   D3E, R20K, V31I, A49P, I72V, L74I, I84L, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, G193E, V201I, L234I, S255NA
Gashnikova (2016)Tyumen10Tyumen10KX640194None   D3E, K14R, R20K, D25E, V31I, I60IM, L63V, I72V, L74I, T112V, S119P, T124S, T125TA, G134N, K136Q, G163E, D167E, V201I, T218TI, L234I, S255N, D256EA
 Tyumen09Tyumen09KX640193None   R20K, I72V, L74I, T112V, S119P, T124S, T125A, G134D, D167E, V201I, L234I, S255NA
 Tyumen08Tyumen08KX640192None   D3E, K7Q, E11D, R20RK, S24N, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218L, L234I, S255NA
 Tyumen29Tyumen29KX640209None   D3E, R20K, S24G, D25E, D41N, I72V, L74I, L101I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen02Tyumen02KX640186None   D3E, K14R, R20K, V31I, L63V, I72V, L74I, S119P, T124S, T125A, G134N, K136Q, D167E, G193E, V201I, T218I, L234I, S255N, D279GA
 Tyumen12Tyumen12KX640195None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen44Tyumen44KX640223None   D3E, R20K, V31I, I72V, L74I, V110VI, K111KR, T112IV, S119P, T124S, T125A, G134N, K136Q, D167E, G193E, V201I, T218I, L234I, S255N, D288NA
 Tyumen05Tyumen05KX640189None   E11D, S24AG, L28I, V37I, L63V, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, D256DEA
 Tyumen03Tyumen03KX640187None   R20K, V32I, L63V, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167DE, V201I, T218I, L234I, S255NA
 Tyumen68Tyumen68KX640243None   R20K, V31I, M50I, I60M, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen35Tyumen35KX640214None   R20K, M50MT, I72V, L74I, T112V, S119P, T124S, T125A, G134D, K136R, D167E, V201I, T218I, L234I, S255NA
 Tyumen07Tyumen07KX640191None   K14R, V31VI, V32I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, H171L, V201I, T218I, L234I, S255NA
 Tyumen43Tyumen43KX640222None   D64N, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen64Tyumen64KX640239None   D3E, R20K, V31I, S39N, H51HR, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T206S, T218I, L234I, K244R, S255NA
 Tyumen72Tyumen72KX640246None   E11D, R20RK, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218TI, L234I, S255N, S283GA
 Tyumen17Tyumen17KX640200None   D3E, R20K, V31I, L63I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, K188KR, V201I, T218I, L234I, S255NA
 Tyumen60Tyumen60KX640235None   V31I, I72V, L74I, A91T, T112I, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, I203M, L234IA
 Tyumen15Tyumen15KX640198None   D3E, K14R, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen61Tyumen61KX640236None   K14R, V32I, L63V, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen24Tyumen24KX640204None   R20K, V31I, I72V, L74I, K111R, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255NA
 Tyumen16Tyumen16KX640199None T66I D3E, E11D, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, D167E, H171Q, V201I, T218I, L234I, S255NA
 Tyumen42Tyumen42KX640221None   D3E, R20K, V31I, L63V, I72V, L74I, T112V, I113V, S119P, T124G, T125A, G134D, K136Q, V150VI, D167E, V201I, L234I, S255N, V260VIA
 Tyumen63Tyumen63KX640238None   D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, G193E, V201I, T218I, L234I, S255N, D279GA
 Tyumen18Tyumen18KX640201None   D3E, V31I, I72V, L74I, T112V, I113V, S119P, T124G, T125A, G134D, K136Q, D167E, H171Q, V201I, L234I, S255NA
 Tyumen25Tyumen25KX640205None   D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen48Tyumen48KX640225None   D3E, E11D, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, D167E, H171Q, V201I, T218I, L234I, S255NA
 Tyumen59Tyumen59KX640234None   E11D, R20K, V31I, L63V, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen75Tyumen75KX640249None   D3E, E11D, R20K, V31I, D41N, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, G163E, D167E, V201I, T218TI, L234I, S255NA
 Tyumen34Tyumen34KX640213None   D3E, E11D, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124G, T125A, G134N, K136Q, D167E, V201I, K211KR, K215N, T218I, L234I, S255NA
 Tyumen06Tyumen06KX640190None   D3E, S17N, S24G, V32I, S39R, L45V, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134N, K136R, G163E, D167E, V201I, T218I, L234I, S255NA
 Tyumen28Tyumen28KX640208None   D3E, R20K, V31I, I72V, L74I, K111R, T112V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen33Tyumen33KX640212None   K14R, L28I, V32I, D41N, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen51Tyumen51KX640227None   D3E, E11D, R20K, V31I, V32I, D41N, K42Q, H51R, I72V, L74I, V110I, T112V, S119P, T124N, T125A, G134N, K136Q, D167E, V201I, L234I, S255N, D278NA
 Tyumen52Tyumen52KX640228None   R20K, V31I, I72V, L74I, P90PS, T112V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen56Tyumen56KX640232None   K14R, V32I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen70Tyumen70KX640245None   E11D, R20K, V31I, I72V, L74I, I84L, E87EK, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, R166RK, D167E, H171L, V201I, L234I, S255NA
 Tyumen54Tyumen54KX640230None   K14R, R20K, V31I, A49G, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen49Tyumen49KX640226None   K7Q, E11D, R20K, V31I, D41N, I72V, L74I, T112V, I113V, S119P, T124G, T125A, G134N, K136Q, D167E, V201I, L234I, D253E, S255NA
 Tyumen69Tyumen69KX640244None   K7KQ, E11D, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen04Tyumen04KX640188None  T97AD3E, K14R, R20K, V31I, V32I, L63V, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, I203M, L234I, S255HA
 Tyumen27Tyumen27KX640207None   D3E, E11D, R20K, V31I, I72V, L74I, T112V, S119P, T124N, T125A, G134N, K136Q, D167E, I200L, V201I, L234I, S255NA
 Tyumen65Tyumen65KX640240None   D3DE, S17N, R20K, D41N, I72V, L74I, T112V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255N, S283GA
 Tyumen58Tyumen58KX640233None   K14R, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen26Tyumen26KX640206None   D3E, R20K, V31I, V32I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen37Tyumen37KX640216None   K7KQ, R20K, V31I, I72V, L74I, K111R, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen30Tyumen30KX640210None   R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen74Tyumen74KX640248None   D3E, E11D, R20K, P30F, V31I, S39R, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134D, K136Q, D167E, V201I, T218L, N222K, L234I, S255NA
 Tyumen38Tyumen38KX640217None   D3E, E11ED, R20K, V31I, V32L, E48EK, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, N222K, L234V, S255NA
 Tyumen66Tyumen66KX640241None   R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V151VG, D167E, V201I, T218I, L234I, S255NA
 Tyumen73Tyumen73KX640247None   D3E, E11D, R20K, V31I, D55DN, E69EK, I72V, L74I, A86AT, K111KR, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, M154MI, D167E, V201I, T218I, L234I, S255N, V259I, S283GA
 Tyumen46Tyumen46KX640224None   D3E, K7Q, E11D, R20K, V31I, V32I, D41N, I60M, I72V, L74I, K111R, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, E152EK, D167E, V201I, T218I, L234I, S255NA
 Tyumen53Tyumen53KX640229None   D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136H, D167E, G193E, V201I, T218I, L234I, S255NA
 Tyumen55Tyumen55KX640231None   R20K, I72V, L74I, T112I, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218L, L234I, S255NA
 Tyumen41Tyumen41KX640220None   D3E, E11D, K14R, R20K, V31I, V32I, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134D, K136Q, D167E, V201I, L234I, S255NA
 Tyumen32Tyumen32KX640211None   D3E, R20K, D41DN, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen14Tyumen14KX640197None   S24G, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, H171Q, V201I, T206S, L234I, S255NA
 Tyumen13Tyumen13KX640196None   K14R, S24G, D25E, V31I, S39C, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, K211R, T218I, L234I, S255NA
 Tyumen40Tyumen40KX640219None   R20K, I72V, L74I, P90PS, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255NA
 Tyumen62Tyumen62KX640237None   D3E, E11D, R20K, A21T, V31I, D64DN, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, I203M, T218I, L234I, S255NA
 Tyumen21Tyumen21KX640202None   K14R, S24G, D25E, S39C, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, K211R, T218I, L234I, S255NA
 Tyumen36Tyumen36KX640215None   D3E, E11D, R20K, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, K215N, L234I, S255NA
Heipertz (2016)NG020382NG020382KX389616None   E11D, H16HR, D25E, V31I, I72V, L74I, T112V, T124A, T125A, V126M, G134D, I135V, K136H, F181L, V201I, T206S, L234I, S283GA
Pandey (2016)NARI-FLS_VB6VB6KT152840None   K14KR, D41N, L45I, I72V, L74I, P90S, L101I, T112V, I113V, T124A, T125A, K136Q, I141V, D167E, V201I, A205S, S283GA
 NARI-FLS_VB15VB15KT152842None   E11D, K14R, S24N, D25E, V31I, V32I, L63I, L74I, L101I, T112V, I113V, S123C, T124N, K136Q, D167E, V201I, S283GA
 NARI-FLS_IVC19-1IVC19-1KT152839None   E11D, K14KR, S24N, V31I, I72V, L74I, T112M, T125A, K136Q, D167E, G193E, V201I, D278N, S283G, D286NA
Rodgers (2017)CG-0086-01VCG-0086-01VKY365208None  T97AV31I, M50I, L74I, L101I, T112V, I113L, T124G, T125A, G134D, T206S, T218S, L234I, S283GA