<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation S230N
Rx II-naive
IncludeMixtures No
References 4
Patients 8
Isolates 8
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Alizon (1986)MALCGMALMALCGX04415None   V31I, L74I, L101I, T112V, I113V, T124A, T125A, G134N, D167E, V201I, I203M, S230N, L234I, S283G, R284GA
Sanders-Buell (2010)047H047HGQ477443None   E11D, R20K, V31I, I60M, I72V, T112V, I113V, S119T, T124A, T125A, V126F, G134S, K136Q, D167E, V201I, S230N, D256N, S283GA
Jahanbakhsh (2012)THR18THR18INTAB716158None   K14R, S17SN, E35Q, S39N, I60M, I72V, T112V, I113V, T124A, T125A, V126F, G134S, I135IV, K136Q, D167EK, V201I, S230N, S283GA
 THR49THR49INTAB716186None  E138EDD6E, K14KR, S17N, E35Q, S39N, I60M, I72V, I84IM, T112V, I113V, T124A, T125A, V126F, I135IV, K136Q, I141IV, D167EK, V201I, S230N, S283GA
 KSH25KSH25INTAB716164None   D6DE, S17SN, M22MR, V31I, S39N, D41DN, I60M, I72V, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, V165VI, D167E, V201I, I203IM, S230N, S283SG, R284RGA
 THR42THR42INTAB716180None   S17N, E35Q, S39N, I60M, I72V, T112V, I113V, T124A, T125A, V126F, G134S, I135V, K136Q, V165VI, D167E, V201I, S230N, S283GA
Inzaule (2018)UGMBAPM098UGMBAPM098MG694095None   S17N, V31I, D41N, I60V, I72V, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, D167E, V201I, I208L, T218S, S230N, S283GA
 KECRHPM089KECRHPM089MG693804None   S17N, V31I, V32I, L45I, I72V, K111R, I113V, T124A, T125A, V126F, K136Q, V165I, D167E, V201I, T206S, S230N, D279G, S283GA