<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation T206S
Rx II-naive
IncludeMixtures No
References 11
Patients 20
Isolates 20
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Gao (1996)92UG03792UG037U51190None   K14R, V31I, I72V, I84V, T112V, I113V, T124A, T125A, G134N, I135V, D167E, V201I, T206S, I208L, N222K, Y226C, L234I, A265V, R269K, S283GA
Kijak (2004)1152NG01CM.1152AY371163None   E11D, K14R, A21T, A23V, S24N, D25E, V31I, M50I, I72V, L101I, T112V, T124A, T125A, G134N, K136Q, V165I, D167E, V201I, T206S, D207E, T218I, I220V, L234I, S283GA
Brennan (2008)A1219A1219EU618361None   K14R, V31I, L101I, T112V, T122I, T124A, T125A, G134N, K136Q, V201I, T206S, L234I, R269K, S283GA
 AB1073AB1073EU618473None   K14R, A21T, V31I, I72V, L101I, T112V, T124G, T125A, G134N, K136Q, D167E, V201I, T206S, I208L, L234I, S283GA
 AB268AB268EU618479None   E11D, K14R, A21T, L28I, V31I, V32I, M50I, I72V, I84L, T112V, I113V, T124A, T125A, V126F, G134S, I135V, K136Q, V201I, T206S, L234I, S255N, S283GA
 AB523AB523EU618481None   V31I, I72V, T112V, I113V, T124A, T125A, G134D, I135V, V201I, T206S, I208M, L234I, S283GA
 ABB43-96ABB43-96EU618530None  T97TAS17N, V31I, L101LI, T112V, T124G, T125A, G134N, K136Q, D167E, V201I, T206S, Y227F, L234I, S255N, D256E, S283GA
 ABB73-96ABB73-96EU618558None   E11D, K14R, A21T, A23V, V31I, D41N, M50I, I72V, T112V, I113V, T124A, T125A, G134D, K136Q, D167E, V201I, T206S, L234I, S283G, D288NA
Van Laethem (2008)AR04-1158AR04-1158EU882801None   E11D, K14R, S24H, V31I, L101I, T112IV, S119P, T122I, T124TA, T125S, I135V, K136Q, V201I, T206S, K215R, L234I, D256E, S283GA
Sichtig (2009)17-E17-EFJ183492None   V31I, L74I, T112V, T124A, T125A, G134N, K136T, D167DE, V201I, T206S, K219N, L234IA
 54-E54-EFJ183555None   V31I, I60IL, I72V, L74I, T112V, I113V, T124A, T125S, V126M, G134N, K136Q, K173KR, I182V, V201I, T206S, I208L, L234IA
Avi (2010)N78N78GQ926823None   S24N, V31I, L74I, L101I, T112V, T124A, G134N, K136Q, V201I, T206S, T218I, L234I, D256E, Y271H, S283GA
Fish (2010)P3509ZAP35GQ872493None   K14R, S24N, S39C, I60M, I72V, T112V, I113V, T124A, T125A, K136Q, V201I, T206S, T218I, Q221R, L234I, S283GA
Tovanabutra (2010)KECst_013KECst_013FJ623485None   K14R, V31I, I72V, L101I, T112V, I113V, S119P, T124A, T125A, I135V, K136Q, D167E, G193E, V201I, T206S, L234I, D278N, S283GA
 KECst_001KECst_001FJ623487None   K14R, V31I, I72V, L101I, T112V, I113V, T124A, T125A, K136R, K156N, G193R, V201I, T206S, A265V, S283GA
Brenner (2011)89898989HQ207784None   E11D, E13D, S24N, D25E, V31I, M50L, L101I, G106A, T112V, S119T, T124TA, K136Q, V165I, D167E, V201I, T206S, L234I, S255NA
Jahanbakhsh (2012)THR19THR19INTAB716159None   K14R, E35Q, S39N, I60M, T112V, I113V, T124A, T125A, K136Q, D167EK, E198Q, V201I, T206S, S230SN, A265AT, R269RK, S283DGA
Reigadas (2013)305305JX425426None   E11D, K14R, S24N, V31I, A91T, E96D, L101I, K103R, T112V, S119R, T124N, T125A, G134N, K136Q, D167E, V201I, T206S, L234I, S283GA
 317317JX425438None   K14R, A21T, S39C, M50R, I72V, L74I, G106A, T112V, S119T, T124A, T125A, V126M, G134N, K136Q, V165I, G193E, V201I, T206S, T210I, T218S, Q221E, L234I, S283GA
 336336JX425457None   V31I, L74LI, L101I, G106GA, T112M, S119SAGT, T122TI, T124A, T125A, G134N, D167E, V201I, T206S, D207E, K211Q, E212A, T218L, K219Q, Q221QK, L234I, S283G, D286NA