<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation I203M
Rx II-naive
IncludeMixtures No
References 11
Patients 21
Isolates 21
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Alizon (1986)MALCGMAL MALCGX04415None   V31I, L74I, L101I, T112V, I113V, T124A, T125A, G134N, D167E, V201I, I203M, S230N, L234I, S283G, R284GA
Watanaveeradej (2003)NP1809NP1809AY262830None   E11D, A21T, V31I, S39N, I72V, L101I, T112I, T124A, T125A, G134N, I135L, K136Q, V201I, I203M, L234I, S283G, D286NA
Njai (2006)MP141199CM.1411AM279396None  T97AV31I, L63M, I72V, L74I, T112V, I113L, T124N, T125A, V126M, G134N, K136Q, L158LF, D167E, V201I, I203M, T218S, L234IA
Rodriguez (2006)1579A1579ADQ083238None  L74MV31I, M50I, I72V, P90Q, L101I, T112V, I113V, T124A, T125A, K136Q, D167E, V201I, I203M, K219R, S283GA
Sanders-Buell (2007)AF10405AF104EF158042None   D6E, K14R, V31I, S39N, I60M, I72V, T112I, I113V, T124A, T125A, V126F, K136H, D167E, V201I, I203M, S283GA
Holzmayer (2009)AH8340AH8340FJ712799None   D6E, K14R, V31VI, K34R, I60IMV, I72V, T112V, I113V, T124A, T125A, G134N, D167E, V201I, I203M, M275V, S283GA
Sichtig (2009)18401840FJ183567None  L74LMK14R, V31VI, V32I, A38AP, L63LV, I72IATV, T112V, T124A, T125A, G134N, I135V, K136Q, V201I, I203M, L234IA
 34693469FJ183576None  L74IMK14R, V31VI, V32I, L63V, T112V, T124A, T125A, G134N, I135V, K136Q, V201I, I203M, L234IA
Avi (2010)N71N71GQ926816None  G163RV31I, L74I, A91T, L101I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, I203M, T218I, L234I, D256E, S283GA
Tovanabutra (2010)KECst_006KECst_006FJ623475None   K14R, V31I, V32I, I72T, L74I, T112V, I113V, S119P, T124S, T125A, K136Q, D167E, V201I, I203M, K219N, N222K, S283GA
 KECst_010KECst_010FJ623491None   K14R, V32I, D41N, M50I, I60M, I72V, T112I, T124A, T125A, K136Q, D167E, V201I, I203M, Q216H, Y227F, S255G, S283GA
Jahanbakhsh (2012)KSH29KSH29INTAB716168None   D6E, K14R, A21AT, M22MI, A23V, E35EQ, S39N, M50MI, I60M, I72IV, T112V, I113V, T124S, T125A, V126F, G134S, K136Q, D167EK, V201I, I203M, I208IM, D232DN, L234LH, S283GA
 SYZ40SYZ40INTAB716178None  L74MD6E, K14R, S17N, N27NI, V31I, E35Q, S39N, I60M, I72V, T112I, I113V, T124A, T125A, V126F, G134S, K136Q, D167E, V201I, I203M, S283GA
 THR02THR02INTAB716143None   K14R, E35Q, S39N, I60M, I72V, L74I, G106GA, K111R, T112V, I113V, T124A, T125A, V126F, G134S, K136Q, I141IF, D167EK, I191IM, S195T, V201I, I203M, S283G, R284RGA
 THR46THR46INTAB716183None   D6E, S17N, L28I, V31I, S39C, I60V, I113IV, T124N, T125M, I203M, I220LA
 THR14THR14INTAB716155None   G4E, V31I, V32I, E35K, S39N, D41N, L45I, D55N, I60M, E69K, G70E, I72V, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, F139T, M154I, R166K, D167E, H171HP, V201I, I203M, L242LF, S283GA
 THR07THR07INTAB716148None  L74LIMVD6E, K14R, R20RG, V31I, S39SN, I60M, K71KR, I72V, T112V, I113V, T124A, T125A, V126F, G134S, I135IV, K136Q, D167E, K173R, V201I, I203M, I204IT, S283GA
 THR15THR15INTAB716156None  R263RKK14R, L28I, V31I, V32I, K34KR, S39N, I60M, I72V, T112V, I113V, T124A, T125A, V126F, G134GS, K136Q, N144NY, D167E, H171HP, R187RK, V201I, I203M, N222K, R231RK, D232DN, K240R, V259VI, A265AT, S283GA
 KSH24KSH24INTAB716163None   D6E, K14R, P30AS, S39C, I60M, I72V, T112A, I113V, T124A, T125A, V126F, K136Q, D167EK, V201I, I203M, I220V, D232DN, L234I, S283GA
Reigadas (2013)600600JX425845None   E11D, K14R, A21T, A23V, V31I, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, I203M, L234I, V260I, S283GA
 1812118121JX451890None   E11D, V31I, I72V, T112V, I113V, S119T, T122TI, T124A, T125A, K136Q, V201I, I203M, L234I, D279GA