<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation E157Q
Rx II-naive
IncludeMixtures No
References 6
Patients 7
Isolates 8
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Dowling (2002)KSM4024KSM4024AF457077None  T97AK14R, A21T, V31I, D41N, L74I, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, E157Q, K160Q, D167E, V201I, Q216H, Y227F, L234V, S283GA
Ntemgwa (2008)775004CA7750EU220698None   K14R, V31I, A80S, Q95P, T112V, T124N, T125A, K136Q, E157Q, K160Q, V201I, L234I, S283GA
Eshleman (2009)161.287161.287FJ480230None   K14R, V31I, I60M, I72V, T112I, I113V, T124TA, T125A, V126F, K127KR, G134N, K136Q, E157Q, K160Q, D167E, V201I, D256DE, S283GA
Brenner (2011)70347034HQ207747None  Q148LPK14R, A23AG, V31I, G59GR, A80S, Q95P, T112V, T124N, T125A, K136Q, N144ND, M154I, E157Q, K160Q, A169AG, G193GR, S195SR, V201I, L234I, S283GA
 77507750HQ207762None   K14R, V31I, A80S, Q95P, T112V, T124N, T125A, K136Q, E157Q, K160Q, V201I, L234I, S283GA
 96379637HQ207799None   K14R, V31I, A80S, Q95P, T112V, T124N, T125A, K136Q, E157Q, K160Q, V201I, R231RT, L234I, S283GA
Jahanbakhsh (2012)KSH28KSH28INTAB716167None   K14R, A21T, A38G, S39N, I60M, I72V, T112V, I113V, T124A, T125A, V126F, G134N, K136Q, E157Q, K160Q, D167EK, I191IM, V201I, K211R, D232DN, L234V, S283G, D288NA
Billings (2016)KE860822V3KE860822V3KT022369None   K14R, S39C, I60M, I72V, T112V, I113V, T124A, T125A, V126F, K136Q, E157Q, K160Q, D167E, G193E, V201I, T218S, Y227F, N254K, S255K, S283GA