<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation T125V
Rx II-naive
IncludeMixtures No
References 6
Patients 9
Isolates 9
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Brennan (2008)628-14628-14EU618268None   K7Q, E11D, A21T, I72V, L101I, T112V, T124A, T125V, G134N, K136Q, D167E, I208L, T218I, L234I, S283G, D286NA
 A1774A1774EU618441None   K14R, A21T, V31I, I72V, L101I, G106A, T112V, T125V, G134N, K136Q, D167E, L234I, D256E, V281M, S283GA
Tovanabutra (2010)KECst_017KECst_017FJ623488None   K7R, K14R, R20K, V31I, I60M, I72V, T112I, I113V, T124A, T125V, K136Q, D167E, V201I, K219N, N222K, V260I, S283GA
Monleau (2012)SK2032SK2032JQ250526None   E11D, A21T, A23V, V31I, D41N, M50I, I72IMV, L101I, T112V, T124A, T125V, G134D, K136Q, D167E, K173R, V176VL, V201I, L234I, S283GA
Reigadas (2013)334334JX425455None   K14R, A21T, V31I, D41DN, I72V, L101I, T112V, T124A, T125V, G134N, K136Q, V165I, D167E, I208L, T218I, L234I, S283GA
 339339JX425460None   K14R, A21T, S39C, M50I, I72V, I84M, L101I, G106A, T112V, T124A, T125V, G134N, K136Q, D167E, V201I, I208L, Q221T, N222T, L234I, S283G, D286VA
 100726100726JX451918None  A128ATK14R, A21T, S24SN, I72V, L101I, T112IV, T125V, G134N, K136Q, L234I, S283SGA
Billings (2016)KE649309V2KE649309V2KT022367None   E10A, K14R, V31I, I72V, L101I, T112V, I113V, S119G, T124A, T125V, K136Q, D167E, K173R, V201I, L234I, A265V, S283GA
Gashnikova (2016)57IN_57KX574445None   R20K, V31I, I60T, T112V, I113V, S119P, T124N, T125V, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, I268VA