<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype A
Gene IN
Mutation T125S
Rx II-naive
IncludeMixtures No
References 6
Patients 7
Isolates 7
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Burns (2002)B1583B1583AF458247None   S17N, V31I, I72V, L101I, T112A, S119P, T122I, T124A, T125S, V201I, D256EA
Van Laethem (2008)AR04-1158AR04-1158EU882801None   E11D, K14R, S24H, V31I, L101I, T112IV, S119P, T122I, T124TA, T125S, I135V, K136Q, V201I, T206S, K215R, L234I, D256E, S283GA
Garrido (2009)123INT-123GU216970None   V31I, M50T, T112V, S119R, T122S, T124N, T125S, K136Q, D167E, V201I, L234IA
Sichtig (2009)54-E54-EFJ183555None   V31I, I60IL, I72V, L74I, T112V, I113V, T124A, T125S, V126M, G134N, K136Q, K173KR, I182V, V201I, T206S, I208L, L234IA
 38003800FJ183602None   K14R, S17N, S24H, V32I, I72V, L101I, T112V, S119P, T122I, T124A, T125S, G134GD, K136KQ, V201I, K215R, N222K, L234I, D256EA
Billings (2016)KE389016V3KE389016V3KT022386None   S24H, V31I, G59R, I72V, L101I, T112V, S119P, T122I, T124A, T125S, K136Q, K160R, V201I, K215R, L234I, A265V, S283GA
Inzaule (2018)KECRHPM124KECRHPM124MG693810None   K14R, S24H, V31I, I60V, I72V, T112V, S119P, T122I, T124A, T125S, I135V, G163E, L234I, D253H, S283GA