<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
425 425 Japan 2005 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, E35DN, M36I, N37DE, R41K, H69K, K70R, L89M  
>425| codons 1-99
PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLENIELPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11T, V35T, T39K, K43E, V60I, S68G, D121H, K122E, D123S, I135T, K173IT, Q174K, D177E, I178IM, T200TA, Q207A, R211S  
>425| codons 1-236
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHP

References
Author Title Citation
Ibe, S Trend of drug-resistant HIV type 1 emergence among therapy-naive patients in Nagoya, Japan: An 8-year surveillance from 1999 to 2006. ARHR, 2008
Fujisaki, S An 11-year surveillance of HIV type 1 subtypes in Nagoya, Japan. ARHR, 2009