<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
452-125040D 452 Uganda 1997 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L       V35I, T39A, E40ED, K49KR, V60I, T69A, D121Y, K122E, I142V, D177E, I178IM, T200TI, Q207G, R211K, V245K, D250E, A272P, K277R, L282C, L283I, I293V, K311KR, S322T  
>452| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICADLEKEGKISRIGPENPYNTPI
FAIKKKDSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLEIGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIRGTKALTEVVPLTEEAE
LELAENREILREPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, M36L, N37NS, R41K, I64V, H69HY  
>452| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYD
QILVEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Church, JD HIV type 1 variants with nevirapine resistance mutations are rarely detected in antiretroviral drug-naive African women with subtypes A, C, and D. ARHR, 2007