Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 452-125040D | 452 | Uganda | 1997 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, M36L, N37NS, R41K, I64V, H69HY |
| >452| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYD QILVEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L | V35I, T39A, E40ED, K49KR, V60I, T69A, D121Y, K122E, I142V, D177E, I178IM, T200TI, Q207G, R211K, V245K, D250E, A272P, K277R, L282C, L283I, I293V, K311KR, S322T |
| >452| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICADLEKEGKISRIGPENPYNTPI FAIKKKDSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIRGTKALTEVVPLTEEAE LELAENREILREPVHGVYYDPTKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Church, JD | HIV type 1 variants with nevirapine resistance mutations are rarely detected in antiretroviral drug-naive African women with subtypes A, C, and D. | ARHR, 2007 |