<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt221 139995 Portugal 2007 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E34Q, E35D, M36I, R41K, G68GE, H69K, K70R, V82I, L89M, I93L  
>139995| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLQDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICEKRAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40D, K43R, V60I, A98S, K122E, D123N, I135T, K173I, Q174K, D177E, V189VI, T200A, I202V, Q207E, R211S, V245Q, E248D, D250E, A272P, V276I, T286A, E291D, V292I, I293V, E297A, V317A, D320E, D324E, Q334L  
>139995| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI
YQYMDDLYIGSDLEIGQHRAKVEELREHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGAYYEPSKELIAEIQKQGLG

References
Author Title Citation
Palma, AC Molecular epidemiology and prevalence of drug resistance-associated mutations in newly diagnosed HIV-1 patients in Portugal. Infect Genet Evol, 2007