<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW102 SW0102 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 77

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V   V106M V179D S48T, S68G, V90I, K103R, D121Y, K122E, D123G, S162C, K173A, D177E, T200A, E203EK, Q207E, R211K  
>SW0102| codons 40-243
EMEKEGKITKIGPENPYNTPVFAIKKKDGTRWRKLVDFRELNKRTQDFWEIQLGIPHPAG
LKKRKSMTVLDVGDAYFSVPLYEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQCSMTKILEPFRAQNPEIDIYQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTPDK
KHQKEPPFLWMGYELHPDKWTVQP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L  
>SW0102| codons 9-99
PLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIPIEICG
KKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008