<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW100 SW0100 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 24

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12TA, I15V, L19I, M36I, N37NS, R41K, L63I, H69K, T74S, L89M, I93L  
>SW0100| codons 4-99
TLWQRPLVAIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYDQII
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K104R, K122E, D123S, I135T, S162C, K173A, Q174K, T200A, Q207E, R211K, F214L  
>SW0100| codons 40-247
EMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKKRSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAI
FQCSMTKILEPFRAKNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDK
KHQKEPPFLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008