<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW092 SW092 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 56

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
V75T, M184V   K103N A98G, P225H S48T, V60I, K122E, D123S, I135L, E138A, K173A, D177E, T200A, R211K, Q242QHR, V245Q  
>SW092| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLTDFRELNKRTQDFWEVQLGIPHPGG
LKKNKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLLKWGFTTPDK
KHQKEHPFLWMGYELHPDKWTVRPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, Q18E, L19T, K20R, E35D, M36I, R41K, H69K, L89M, I93L  
>SW092| codons 4-99
TLWQRPLVTIKVGGETREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008