<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW090 SW090 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T|LPV NA
2 3TC+AZT+EFV 137

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, E35D, M36I, R41K, K45R, D60E, I62V, L63P, H69K, V82I, L89M, I93L  
>SW090| codons 4-99
TLWQRPLVSIKVGGQTKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYEQVP
IEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215TI, K219E K103N, V106M   S48T, V60I, T69N, W88C, K122E, D123S, T165L, K173T, Q174K, T200A, I202V, Q207E, R211K, F214L, V245E F130FL
>SW090| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFCEVQLGIPHPAG
LKKNKSMTVLDVGDAYFSVPLDESFRKYTALTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQSSMLKILEPFRTKNPDIVIYQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLITPDE
KHQKEPPFLWMGYELHPDKWTVQPIELP

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008