Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SW088 | sw088 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | 52 |
| 2 | 3TC+AZT+NVP | 49 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70KR, M184V, T215Y | V106M, G190A | S48T, K102M, K122E, D123G, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q |
| >sw088| codons 40-247 EMEKEGKITKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKMKKSMTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTRILEPFRAQNPEIVIYQYVDDLYVASDLEIGQHRAKIEELREHLLKWGFYTPDK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, N37D, R41K, D60E, L63I, H69K, L89M, I93L |
| >sw088| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYEQII IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |