<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW088 sw088 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV 52
2 3TC+AZT+NVP 49

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KR, M184V, T215Y   V106M, G190A   S48T, K102M, K122E, D123G, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q  
>sw088| codons 40-247
EMEKEGKITKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKMKKSMTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQSSMTRILEPFRAQNPEIVIYQYVDDLYVASDLEIGQHRAKIEELREHLLKWGFYTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, N37D, R41K, D60E, L63I, H69K, L89M, I93L  
>sw088| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYEQII
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008