<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW087 sw087 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T NA
2 3TC+AZT+EFV 70

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184MI   K103N, M230ML V108VI V60I, K122E, I135V, K166R, K173A, Q174N, D177E, T200A, Q207E, R211K, V245Q  
>sw087| codons 40-247
EMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKNKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAI
FQSSMTRILEPFRANNPEIVIYQYIDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDK
KHQKEPPFLWLGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, K14KR, I15V, L19V, M36I, R41K, L63P, H69K, L89LM, I93L  
>sw087| codons 4-99
TLWQRPLVSIRVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008